Taro Takami

Takami Taro | Taro Takami

Affiliation and department：
Job title： Professor
Homepage URL (1)： https://www.ichinai-yamaguchi.jp/

Research field (1)： Gastroenterology

Research keywords (21)：骨髄細胞 , 肝硬変症 , 肝発癌 , ゼブラフィッシュ , メダカ , 肝線維化 , 漢方薬 , Maid , 非アルコール脂肪肝炎 , 肝発がん , 修復再生療法 , 非アルコール性脂肪性肝炎 , 肝細胞癌 , Maid KO mice , 遺伝子治療 , HTVi法 , medaka , 遺伝子導入法 , ABMi療法 , 肝臓病 , 肝再生

Research theme for competitive and other funds (29)：

2023 - 2026 iPS細胞から誘導した間葉系幹細胞由来細胞外小胞によるセルフリー肝臓再生療法の開発
2023 - 2026 間葉系幹細胞の作用を洗練・集約化した抗線維化microRNA封入脂質ナノ粒子の開発
2022 - 2025 The cell identification research of bone marrow drived liver repaired cell in the new liver regeneration therapy
2020 - 2024 新規骨髄由来肝臓修復細胞による肝臓再生療法の開発
2020 - 2024 線維性腸管狭窄に対するメカニズムの解明と臨床応用への検討

2020 - 2023 The development research of liver regeneration therapy used bone marrow drived liver repaired cell

2020 - 2023 鉄除去により強制的に変化させた代謝を標的とした新規抗癌併用療法の開発

2020 - 2023 高感度メチル化解析法による新たな肝癌診断スクリーニング検査の構築

2020 - 2023 抗線維化作用増強exosomeを用いた継続型低侵襲肝臓再生療法の開発

2020 - 2023 肝予備能不良進行肝細胞癌に対する鉄キレート剤と再生療法によるハイブリッド療法開発

2018 - 2021 二種類の骨髄由来肝臓修復細胞による効率的な肝臓再生療法の開発

2017 - 2020 The development of liver regeneration therapy with higher therapeutic effects on liver cirrhosis using a middle-large size liver cirrhosis model.

2017 - 2020 Development of cell-free liver regeneration therapy with the anticipatory method to culture higher-quality MSCs for liver cirrhosis

2016 - 2019 Effects of a novel oral iron chelator on refractory digestive system cancers

2016 - 2018 Development of anti-fibrotic therapies for liver fibrosis by the regulation of Rho family GTPases of macrophages.

2015 - 2018 The analysis and identification of bome marrow drived liver repair cell

2014 - 2017 Basic research to develop next generation cell therapy for improvement of liver fibrosis.

2014 - 2017 Research and development for liver regeneration therapy with higher-therapeutic effects using the higher-functioning cultured bone marrow mesenchymal stem cells

2013 - 2017 Utility of herbal medicine for remission maintenance therapy of ulcerative colitis

2013 - 2016 Development of Medaka Model for Analysis of Angiogenesis and Kupffer cell

2012 - 2015 The analysis of small bone marrow drived liver repair cell

2012 - 2014 Development of the analytical method of the cancer stem cell using the ATP sensor in the cell

2012 - 2014 Basic studies into development of novel preventive and regenerative therapy for hepatocarcinogenic cirrhosis using bone marrow-derived cells having redox-regulatory capacity

2011 - 2012 Basic research for chronotherapy focused on liver regeneration andliver steatosis by circadian clock

2010 - 2012 The basic research of the development of future generation cell therapy used bone marrow derived liver repaid cell

2010 - 2012 Both Herbal medicine Bofu-tsusho-san (TJ-62) and Dai-saiko-to (TJ-8) prevent liver fibrosis and hepatocarcinogenesis in rat liver cirrhosis.

2010 - 2011 Development of new gene transfer system for small fish

2009 - 2010 非アルコール性脂肪性肝炎関連発癌に対する戦略的研究

2009 - 2010 Basic researches for developing new liver regeneration therapy using cultured autologous bone marrow derived cells in decompensated liver cirrhosis patients with hepatocellular carcinomas.

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Papers (246)：

Hiroto Matsui, Tatsuya Ioka, Tsuyoshi Takahashi, Toru Kawaoka, Yoshinari Maeda, Noboru Yahara, Hidefumi Kubo, Taku Nishimura, Toshihiro Inokuchi, Eijiro Harada, et al. Multicenter Prospective Cohort Study of Neoadjuvant Chemotherapy for Borderline Resectable Pancreatic Cancer (YPB-001). Pancreas. 2024
Yurika Yamauchi, Issei Saeki, Koichi Fujisawa, Maho Egusa, Natsuko Nishiyama, Tsuyoshi Fujioka, Daiki Kawamoto, Ryo Sasaki, Tatsuro Nishimura, Norikazu Tanabe, et al. Varying impact of lenvatinib or sorafenib therapy on skeletal muscle loss in patients with hepatocellular carcinoma. Oncology. 2024
Atsuyuki Saisyo, Shinichi Hashimoto, Haku Ishida, Koichi Kashibe, Tomoyuki Oka, Yasushi Hirano, Miwako Takasago, Yutaka Uchida, Naoto Okada, Taro Takami, et al. Treatment of Inflammatory Bowel Disease with Biologics in Japan: A Single-Center, Retrospective Pharmacoeconomic Study. Biological & pharmaceutical bulletin. 2024. 47. 1. 232-239
Shogo Amano, Seiji Kaino, Shuhei Shinoda, Hirofumi Harima, Toshihiko Matsumoto, Koichi Fujisawa, Taro Takami, Naoki Yamamoto, Takahiro Yamasaki, Isao Sakaida. Retraction Note: Invasion inhibition in pancreatic cancer using the oral iron chelating agent deferasirox. BMC cancer. 2023. 23. 1. 1218-1218
Yuki Tahata, Hayato Hikita, Satoshi Mochida, Nobuyuki Enomoto, Akio Ido, Hidekatsu Kuroda, Daiki Miki, Masayuki Kurosaki, Yoichi Hiasa, Ryotaro Sakamori, et al. Posttreatment liver function, but not baseline liver function stratifies patient survival after direct-acting antiviral treatment in decompensated cirrhosis with hepatitis C virus. Journal of gastroenterology. 2023. 58. 12. 1211-1221

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MISC (566)：

佐々木嶺, 石川剛, 西山夏子, 川本大樹, 西村達朗, 高見太郎. C型肝硬変症に対する抗ウイルス療法後の門脈圧亢進症に関する検討. 日本門脈圧亢進症学会雑誌. 2023. 29. 3
石川剛, 西山夏子, 川本大樹, 佐々木嶺, 西村達朗, 高見太郎. Portosystemic shunt syndromeに対するBRTOの適応を考える~Point of No Returnの定量化を目指して~. 日本門脈圧亢進症学会雑誌. 2023. 29. 3
桐原愛果, 石川剛, 西山夏子, 川本大樹, 佐々木嶺, 西村達朗, 高見太郎. IVRと薬物療法により病態制御に成功したPoPHの1例. 日本門脈圧亢進症学会雑誌. 2023. 29. 3
西村達朗, 石川剛, 西山夏子, 川本大樹, 佐々木嶺, 高見太郎. HVPGの非侵襲的代替マーカーの探索と長期予後の層別化. 日本門脈圧亢進症学会雑誌. 2023. 29. 3
西山夏子, 石川剛, 川本大樹, 佐々木嶺, 西村達朗, 高見太郎. 高度門脈圧亢進症および多発肝細胞癌を合併した非代償性肝硬変症に対する集学的治療. 日本門脈圧亢進症学会雑誌. 2023. 29. 3

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Patents (10)：

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Professional career (1)：

医学博士 (山口大学)

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