Rchr
J-GLOBAL ID:201301054442830243   Update date: Mar. 05, 2024

Ishiwata Akihiro

Ishiwata Akihiro
Research field  (2): Biochemistry ,  Molecular biochemistry
Research keywords  (5): 希少糖合成 ,  多糖合成 ,  複合糖質 ,  立体選択的グリコシル化反応 ,  細菌糖鎖
Research theme for competitive and other funds  (4):
  • 2018 - 2021 Study on synthetic glycans complexed with glycosidase foe NMR analysis of the active site
  • 2014 - 2017 結核菌類骨格成分複合糖質の合成研究
  • 2010 - 2012 多分岐複合糖質糖鎖化学合成へのアプローチ
  • 2006 - 2007 細菌表層糖タンパク質合成と抗生物質の新規標的としての糖鎖生合成の解析プローブ創製
Papers (102):
  • Qian Xiao, Sixian Fang, Jiaming Ao, Xiaoya Zhao, Cai Huang, Yuhua Liu, Yichu Nie, Akihiro Ishiwata, Katsunori Tanaka, Wenbin Deng, et al. B(C6F5)3-Catalyzed Stereoselective 1,2-cis Arabinofuranosylation with a Conformationally Constrained Donor. ACS Omega. 2024
  • Yudai Ode, Ambara R. Pradipta, Akihiro Ishiwata, Akihiro Nambu, Kazunobu Ohnuki, Hiroshi Mizuma, Hiromitsu Haba, Katsunori Tanaka. Metallic radionuclide-labeled tetrameric 2,6-diisopropylphenyl azides for cancer treatment. Chemical Communications. 2024
  • Kiyotaka Fujita, Hanako Tsunomachi, Pan Lixia, Shun Maruyama, Masayuki Miyake, Aimi Dakeshita, Kanefumi Kitahara, Katsunori Tanaka, Yukishige Ito, Akihiro Ishiwata, et al. Bifidobacterial GH146 β-l-arabinofuranosidase for the removal of β1,3-l-arabinofuranosides on plant glycans. Applied Microbiology and Biotechnology. 2024. 108. 199
  • Bruno Di Geronimo, Toma Kashima, Akihiro Ishiwata, Katsunori Tanaka, Pedro Alejandro Sánchez-Murcia, Kiyotaka Fujita, Shinya Fushinobu, Santiago Alonso-Gil. GH172 difructose dianhydride I synthase: A two-stepped journey via glycosylation and cyclization using QM/MM metadynamics. 2023
  • Valentina Borlandelli, Wendy Offen, Olga Moroz, Alba Nin-Hill, Nicholas McGregor, Lars Binkhorst, Akihiro Ishiwata, Zachary Armstrong, Marta Artola, Carme Rovira, et al. β-l-Arabinofurano-cyclitol Aziridines Are Covalent Broad-Spectrum Inhibitors and Activity-Based Probes for Retaining β-l-Arabinofuranosidases. ACS Chemical Biology. 2023. 18. 12. 2564-2573
more...
MISC (147):
  • 石渡明弘, 藤田清貴, 伏信進矢, 田中克典, 伊藤幸成. Synthesis and analysis of the mode of action of GH127/146 β-L-arabinofuranosidase inhibitors. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
  • 綿本早希, 佐野加苗, 高森寛人, 石渡明弘, 田中克典, 武田陽一. Synthetic study of sucrose mimetic disaccharide by intramolecular aglycon transfer. 日本糖質学会年会要旨集. 2023. 42nd
  • 石渡明弘, 成田覚, 藤田清貴, 伏信進矢, 田中克典, 伊藤幸成. Study on analysis of mechanism of β-L-arabinofuranosidase using inhibitor probes. 日本糖質学会年会要旨集. 2023. 42nd
  • 佐々木優紀, 松尾綾子, 橋口実々花, 藤村花乃子, 石渡明弘, 越野広雪, 田中克典, 伊藤幸成, 北原兼文, 藤田清貴. セヤル種アラビアガムに作用するビフィズス菌由来の新規糖質加水分解酵素の解析. 応用糖質科学. 2023. 13. 3
  • 福島陸, 石渡明弘, 藤田清貴, 荒川孝俊, 山田千早, 伏信進矢, 伏信進矢. 結核菌が持つ特徴的な細胞壁多糖を分解する新規酵素の構造と機能の解明. 応用糖質科学. 2023. 13. 3
more...
Lectures and oral presentations  (23):
  • Chemical approaches toward understanding the functions of novel enzymes degrading bacterial and plant glycans
    (32nd Glyco-lipidologue seminar 2023)
  • 微生物や植物の複合糖質の合成研究から糖質分解酵素の機能解明への化学的アプローチ
    (第7回生体分子化学セミナー 2023)
  • 細菌や植物の糖質分解酵素の機能解明への化学的アプローチ
    (2023年度分子研異分野技術交流セミナー(第2回)~ 創薬リード探索の先端と計測技術 ~ 2023)
  • Chemical Approaches Toward Understanding Cysteine Glycosidase Catalysis
    (Seventh International Conference on Catalysis and Chemical Engineering 2023)
  • Synthesis of L-arabinofuranoside derivatives for the analysis of novel β-L-arabinofuranosidases and its homologues.
    (Asian Carbohydrate Chemistry and Glycobiology Webinar 2022)
more...
Work history (8):
  • 2018/04 - 現在 Tokyo University of Science Faculty of Science, Division 1 Chemistry Part-time lecturer
  • 2015/04 - 現在 RIKEN
  • 2021/04 - 2021/09 Tokyo University of Science Faculty of Science Division II Part-time lecturer
  • 2009/04 - 2021/09 Shibaura Institute of Technology College of Engineering and Design Part-time lecturer
  • 2007/04 - 2014/03 RIKEN Senior Research Scientist
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Committee career (12):
  • 2021/07 - 現在 GlycoPOD ver 2, JCGG Editor
  • 2014/01 - 2022/03 Trends in Glycoscience and Glycotechnology Associate Editor
  • 2017/01 - 2019/12 Trends in Glycoscience and Glycotechnology Handling Editor
  • 2014/01 - 2019/12 Forum: Carbohydrates Coming of Age Associate Secretaries
  • 2014/01 - 2019/12 Forum: Carbohydrates Coming of Age 幹事
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Awards (3):
  • 2009/03 - 日本化学会 第23回若い世代の特別講演会講演者証
  • 2008/08 - 日本糖質学会 奨励賞
  • 2007/10 - 東京糖鎖研究会 奨励賞
Association Membership(s) (9):
JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  THE JAPANESE SOCIETY OF APPLIED GLYCOSCIENCE ,  Forum: Carbohydrates Coming of Age ,  American Chemical Society ,  JAPAN SOCIETY FOR BIOSICENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  THE JAPANESE PEPTIDE SOCIETY ,  THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN ,  THE CHEMICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH
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