Hirata Yusuke

ヒラタユウスケ | Hirata Yusuke

Affiliation and department：
Job title：助教

Research field (3)： Molecular biology , Cell biology , Pharmaceuticals - health and biochemistry

Research theme for competitive and other funds (5)：

2020 - 2023 トランス脂肪酸の分子病態基盤に基づく毒性リスク評価および画期的予防・治療法の開発
2018 - 2020 Development of prevention and treatment strategies for trans-fatty acid-related diseases based on novel toxicity mechanisms
2020 - 2020 Regulatory mechanisms for cell death and inflammatory signaling mediated by the diversity of membrane fatty acid species
2015 - 2017 Elucidation of the regulatory mechanisms of ASK1 ubiquitination for developing a new treatment strategy for ASK1-related diseases
2009 - 2011 生体膜脂肪酸環境の感知機構および恒常性維持機構の解明

Papers (36)：

Tomohiro Kagi, Aya Inoue, Takuya Noguchi, Wakana Suzuki, Saya Takano, Kohei Otani, Rio Naganuma, Yuto Sekiguchi, Yusuke Hirata, Sawako Shindo, et al. The NLRP3 Inflammasome Is a Major Cause of Acute Renal Failure Induced by Polypeptide Antibiotics. The Journal of Immunology. 2024. 212. 1-12
Takumi Yokosawa, Sayoko Miyagawa, Wakana Suzuki, Yuki Nada, Yusuke Hirata, Takuya Noguchi, Atsushi Matsuzawa. The E3 Ubiquitin Protein Ligase LINCR Amplifies the TLR-Mediated Signals through Direct Degradation of MKP1. Cells. 2024. 13. 8. 687-687
Yusuke Hirata, Eikan Mishima. Membrane Dynamics and Cation Handling in Ferroptosis. Physiology. 2024. 39. 2. 73-87
Shuhei Hamano, Takuya Noguchi, Yukino Asai, Ryo Ito, Ryuto Komatsu, Tetsu Sato, Aya Inoue, Tomoe Maruyama, Tada-aki Kudo, Yusuke Hirata, et al. Aggregability of the SQSTM1/p62-based aggresome-like induced structures determines the sensitivity to parthanatos. Cell Death Discovery. 2024. 10. 1. 74
Yusuke Hirata, Ryota Kojima, Ryo Ashida, Yuki Nada, Shinnosuke Kimura, Emiko Sato, Takuya Noguchi, Atsushi Matsuzawa. Industrially produced trans-fatty acids are potent promoters of DNA damage-induced apoptosis. The Journal of Toxicological Sciences. 2024. 49. 1. 27-36

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MISC (121)：

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Education (2)：

2007 - 2012 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Biology
- 2007 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy

Professional career (1)：

博士(薬学) (東京大学)

Work history (4)：

2014/10 - 現在 Tohoku University Graduate School of Pharmaceutical Sciences
2021/08 - 2022/07 The Hospital for Sick Children Cell Biology Visiting Researcher
2012/04 - 2014/09 微生物病研究所特任研究員
2009/04 - 2012/03 東京大学薬学系研究科博士後期課程日本学術振興会特別研究員(DC1)

Committee career (3)：

2023/02 - 現在日本生化学会「生化学」誌企画委員会企画委員
2022/04 - 現在日本薬学会環境・衛生部会研究戦略委員会委員
2016/04 - 2019/03 日本薬学会環境・衛生部会若手活性化小委員会委員

Awards (10)：

2022/11 - レドックスR&D戦略委員会第2回若手シンポジウム<特別枠の部>敢闘賞
2021/07 - 東北大学大学院薬学研究科 2021年度東北大学大学院薬学研究科長賞
2020/12 - 日本薬学会 2021年度日本薬学会奨励賞
2020/07 - 東北大学大学院薬学研究科 2020年度東北大学大学院薬学研究科長賞
2019/09 - 日本薬学会環境衛生部会 2019年度日本薬学会環境衛生部会部会賞・金原賞

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Association Membership(s) (5)：

SOCIETY FOR FREE RADICAL RESEARCH JAPAN , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE BIOCHEMICAL SOCIETY , THE JAPANESE SOCIETY OF TOXICOLOGY

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