Taguchi Hiroaki

タグチヒロアキ | Taguchi Hiroaki

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/20549068.ja.html

Research field (1)： Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (7)：

2023 - 2026 Analysis of cholesterol uptake and transport from host serum in pathogenic fungi
2021 - 2024 Development of bifunctional catalytic antibody aiming at innovative therapeutic drug for Alzheimer's disease
2019 - 2022 新規抗真菌薬の創出を目指した病原性真菌の鉄代謝ネットワークの解析
2018 - 2021 認知症治療に向けた2機能型スーパー抗体酵素の開発
2018 - 2021 Development of innovative tauopathy therapeutic agents using catalytic antibodies

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Papers (46)：

Emi HIFUMI, Hiroaki TAGUCHI, Tamami NONAKA, Taizo UDA. Direct conversion of a general antibody to its catalytic antibody and corresponding applications -Importance and role of Pro95 in CDR-3-. Proceedings of the Japan Academy, Series B. 2023. 99. 6. 155-172
Tamami Nonaka, Hiroaki Taguchi, Taizo Uda, Emi Hifumi. Obtaining Highly Active Catalytic Antibodies Capable of Enzymatically Cleaving Antigens. International Journal of Molecular Sciences. 2022. 23. 22. 14351-14351
Emi Hifumi, Tamami Nonaka, Hiroaki Taguchi, Taizo Uda. A new catalytic site functioning in antigen cleavage by H34 catalytic antibody light chain. Scientific Reports. 2022. 12. 1
Emi Hifumi, Hiroaki Taguchi, Tamami Nonaka, Takunori Harada, Taizo Uda. Finding and characterizing a catalytic antibody light chain, H34, capable of degrading the PD-1 molecule. RSC Chemical Biology. 2021. 2. 1. 220-229
Emi Hifumi, Hiroaki Taguchi, Haruna Tsuda, Tetsuro Minagawa, Tamami Nonaka, Taizo Uda. A new algorithm to convert a normal antibody into the corresponding catalytic antibody. Science advances. 2020. 6. 13. eaay6441

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MISC (35)：

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Professional career (1)：

Work history (2)：

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