Tachibana Masashi

タチバナマサシ | Tachibana Masashi

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/80513449.ja.html

Research field (2)： Pharmaceuticals - health and biochemistry , Immunology

Research keywords (7)：がんと代謝 , MDSC , 自己免疫疾患 , T_<reg> , 制御性T細胞 , Foxp3 , IPEX症候群

Research theme for competitive and other funds (10)：

2022 - 2025 Regulation of myeloid-derived suppressor cells by palmitic acid metabolism for next-generation cancer immunotherapy
2022 - 2024 血管を経由する新発想での臓器の脱線維化技術の開発
2021 - 2024 Elucidation of oncolytic virus-mediated intratumorl infiltration of immune cells and development of further promotion methods
2019 - 2022 脂肪酸代謝から解き明かす骨髄由来免疫抑制細胞の制御メカニズムとがん治療への応用
2015 - 2018 Prediction and prevention of serious systemic diseases induced by local infection of bacteria

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Papers (84)：

Sena Ikemoto, Fuminori Sakurai, Sora Tokuoka, Tomoki Yamashita, Kosuke Takayama, Kazuaki Hoshi, Takahiro Okabe, Issei Sumiyoshi, Shinsaku Togo, Kazuhisa Takahashi, et al. Novel conditionally replicating adenovirus-mediated efficient detection of circulating tumor cells in lung cancer patients. PLOS ONE. 2023. 18. 10. e0286323-e0286323
Zhiqi Xie, Haoyang Zhou, Masanori Obana, Yasushi Fujio, Naoki Okada, Masashi Tachibana. Myeloid-derived suppressor cells exacerbate poly(I:C)-induced lung inflammation in mice with renal injury and older mice. Frontiers in immunology. 2023. 14. 1243851-1243851
Haoyang Zhou, Zhiqi Xie, Naosuke Morikawa, Fuminori Sakurai, Hiroyuki Mizuguchi, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana. Modified method for differentiation of myeloid-derived suppressor cells in vitro enhances immunosuppressive ability via glutathione metabolism. Biochemistry and biophysics reports. 2023. 33. 101416-101416
Maho Eguchi, Seiya Hirata, Ikuho Ishigami, Naomi Shuwari, Ryosuke Ono, Masashi Tachibana, Masato Tanuma, Atsushi Kasai, Hitoshi Hashimoto, Ken-Ichi Ogawara, et al. Pre-treatment of oncolytic reovirus improves tumor accumulation and intratumoral distribution of PEG-liposomes. Journal of controlled release : official journal of the Controlled Release Society. 2023. 354. 35-44
Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, et al. Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 3. e2213317120

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MISC (46)：

謝智奇, 周浩洋, 奥崎大介, 岡田直貴, 立花雅史. G-CSFはGGT1を介して骨髄由来免疫抑制細胞の免疫抑制能を増強させる. 日本薬学会年会要旨集. 2022. 142年会. 28I-am11
立花雅史, 立花雅史, 謝智奇, 周浩洋, 奥崎大介, 奥崎大介, 岡田直貴. G-CSFによるGGT1依存的な骨髄由来免疫抑制細胞の免疫抑制能増強. がんと代謝研究会プログラム&抄録集. 2022. 8th
立花雅史, 立花雅史, 奥崎大介, 奥崎大介, 岡田直貴. HDAC inhibitors inhibit invasion of monocytic myeloid-derived suppressor cells into hepatocellular carcinoma. 日本癌学会学術総会抄録集(Web). 2022. 81st
XIE Zhiqi, 奥崎大介, 奥崎大介, 岡田直貴, 立花雅史, 立花雅史. HMGB1-TLR4 signal enhances proliferation and immunosuppressive function of MDSCs. 日本薬学会年会要旨集(Web). 2021. 141st
藤原健人, 中井翔, 安田直弘, 王谷英達, 濱田健一郎, 竹中聡, 立花雅史, 岡田直貴. Research on efficacy and safety prediction of tumor vessel-injuring CAR-T cell therapy for soft tissue sarcoma. 日本薬学会年会要旨集(Web). 2020. 140th

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Books (3)：

アグリバイオ
北隆館 2020
Medical Science Digest
ニューサイエンス社 2020
Drug Delivery System -Recent Progress of Tissue, Intracellular and Intranuclear Delivery Technology for Biopharmaceutical Development-
2018

Lectures and oral presentations (5)：

骨髄由来免疫抑制細胞を介した免疫毒性発現に関する研究
(第28回日本免疫毒性学会学術年会 2021)
飽和脂肪酸による骨髄系細胞分化制御とがん退縮効果
(第6回がんと代謝研究会 2018)
Inhibition of myeloid-derived suppressor cell differentiation by saturated fatty acids
(第12回システム生物医学研究会 2018)
HMGB1-TLR4シグナルによる骨髄由来免疫抑制細胞の機能制御
(第67回近畿支部総会・大会 2017)
粘膜免疫誘導型ワクチンとしてのアデノウイルスベクター
(第33回日本DDS学会学術集会 2017)

Education (3)：

2004 - 2008 Yokohama City University Graduate Graduate School of Medicine
2002 - 2004 大阪大学大学院薬学研究科博士前期課程応用医療薬科学専攻
1998 - 2002 Osaka University School of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Work history (7)：

2024/04 - 現在 Ritsumeikan University College of Llife Science Department of Biomedical Sciences
2022/08 - 2024/03 Osaka University Graduate School of Pharmaceutical Sciences
2016/05 - 2024/03 (兼)大阪大学国際医工情報センター
2017/10 - 2022/07 Osaka University
2016/04 - 2017/09 Osaka University

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Committee career (2)：

2022/10 - 現在日本免疫毒性学会広報委員
2018/10 - 現在日本免疫毒性学会評議員

Awards (7)：

2022/03 - 日本薬学会 2021 Top Reviewer Award for BPB
2021/04 - 2021年度日本免疫毒性学会奨励賞
2019/11 - 大阪大学賞(若手教員部門)
2018/01 - 第1回がんと代謝研究会若手優秀賞
2017/09 - 第24回日本免疫毒性学会学術年会年会賞

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Association Membership(s) (9)：

International Cytokine & Interferon Society , 日本がん免疫学会 , THE JAPANESE SOCIETY FOR VACCINOLOGY , 日本免疫毒性学会 , THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN , 日本DDS学会 , THE JAPANESE CANCER ASSOCIATION , THE PHARMACEUTICAL SOCIETY OF JAPAN , JAPANESE SOCIETY FOR IMMUNOLOGY (JSI)

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