Rchr
J-GLOBAL ID：201301071197136443
Update date: Jan. 30, 2024
Ken Takahashi
タカハシ ケン | Ken Takahashi
Homepage URL (1)：
http://kaken.nii.ac.jp/d/r/60594372.ja.html
Research field (1)：
Gastroenterology
Research theme for competitive and other funds (4)：
- 2020 - 2023 Preclinical study of near-infrared photoimmunotherapy for pancreatic cancer that incorporates nanoparticulate TLR9 agonist K3-SPG
- 2017 - 2020 Preclinical study of in situ vaccine immunotherapy for hepatocellular carcinoma targeting TLR9 and RIG-I
- 2013 - 2016 Comprehensive analysis of immune response in hapatitis B using novel disease mouse model
- 2011 - 2012 Dissecting themechanism of plasmacytoid dendritic cell activation triggered by hepatitis C virus-infected cells
Papers (99)：
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Soichi Arasawa, Haruhiko Takeda, Atsushi Takai, Eriko Iguchi, Yuji Eso, Takahiro Shimizu, Ken Takahashi, Taiki Yamashita, Yoshihide Ueda, Hiroyuki Marusawa, et al. Evolutional transition of HBV genome during the persistent infection determined by single-molecule real-time sequencing. Hepatology communications. 2023. 7. 3. e0047
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中野 重治, 高井 淳, 上野 真行, 網野 遙, 井上 貴裕, 伊藤 卓彦, 寺村 茉利, 三嶋 眞紗子, 熊谷 健, 井口 恵里子, et al. ミスマッチ修復遺伝子MSH2の欠損は炎症性肝発癌を促進する. 日本消化器病学会雑誌. 2022. 119. 臨増大会. A771-A771
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上野 真行, 竹田 治彦, 高井 淳, 恵荘 裕嗣, 中野 重治, 高橋 健, 田浦 康二朗, 波多野 悦朗, 妹尾 浩. 肝癌の発生・進展過程における体細胞変異の蓄積に、ミスマッチ修復異常(dMMR)はどのように寄与しているか?. 肝胆膵. 2022. 85. 1. 148-149
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Ken Kumagai, Takahiro Shimizu, Atsushi Takai, Nobuyuki Kakiuchi, Yasuhide Takeuchi, Tomonori Hirano, Haruhiko Takeda, Aya Mizuguchi, Mari Teramura, Takahiko Ito, et al. Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization. Cancer research. 2022. 82. 9. 1712-1723
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Fumiyasu Nakamura, Haruhiko Takeda, Yoshihide Ueda, Atsushi Takai, Ken Takahashi, Yuji Eso, Soichi Arasawa, Eriko Iguchi, Takahiro Shimizu, Masako Mishima, et al. Mutational spectrum of hepatitis C virus in patients with chronic hepatitis C determined by single molecule real-time sequencing. Scientific reports. 2022. 12. 1. 7083-7083
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MISC (52)：
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恵荘裕嗣, 竹田治彦, 高井淳, 高橋健, 妹尾浩. Initial experience and predictors of response to Atezolizumab plus Bevacizumab combination therapy for hepatocellular carcinoma. 肝胆膵. 2022. 84. 4
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西尾太宏, 小山幸法, 小木曾聡, 楊知明, 福光剣, 石井隆道, 恵荘裕嗣, 高井淳, 高橋健, 瀬尾智, et al. Conversion surgery after lenvatinib therapy for unresectable hepatocellular carcinoma. 肝胆膵. 2022. 84. 4
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恵荘裕嗣, 中野重治, 三嶋眞紗子, 井口恵里子, 竹田治彦, 高井淳, 高橋健, 妹尾浩. Atezolizumab+Bevacizumab奏効後根治的にTACEを追加した一例. 日本肝がん分子標的治療研究会プログラム・抄録集. 2021. 24th
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竹田治彦, 高井淳, 恵荘裕嗣, 高橋健, 田浦康二朗, 波多野悦朗, 喜多竜一, 丸澤宏之, 藤本明洋, 妹尾浩. 多段階発癌におけるミスマッチ修復異常関連体細胞変異シグネチャーの抽出. 日本肝がん分子標的治療研究会プログラム・抄録集. 2021. 24th
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恵荘裕嗣, 中野重治, 三嶋眞紗子, 井口恵里子, 竹田治彦, 高井淳, 高橋健, 妹尾浩. Atezolizumab+Bevacizumab併用療法の初期治療成績. 日本肝がん分子標的治療研究会プログラム・抄録集. 2021. 24th
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Books (6)：
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PD-1/PD-L1
2020
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Evolving Immunotherapy Approaches for Hepatocellular Carcinoma. Takahashi K, Marusawa H. Molecular Diagnosis and Targeting for Thoracic and Gastrointestinal Malignancy
Springer, Singapore 2018
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Importance of anti-HBs antibody in hepatitis B reactivation
2013
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Introduction to foreign laboratory
2013
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Discoveries concerning new mechanisms for the origin and dissemination of infectious diseases Baruch Samuel Blumberg
Medical Review 2013
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Lectures and oral presentations (2)：
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In situ vaccine immunotherapy for gastrointestinal cancers using novel nanoparticulate TLR9 agonist K3-SPG
(DDW2020 2020)
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Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection
(16th International Symposium on Hepatitis C Virus and Related Viruses 2009, NICE, France 2009)
Work history (1)：
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