YUJI MORIMOTO

モリモトユウジ | YUJI MORIMOTO

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/10449069.ja.html

Research field (5)： Medical systems , Dermatology , Biomaterials , Biomedical engineering , General surgery, pediatric surgery

Research keywords (19)：内視鏡 , ICGラクトソーム , 光温熱治療 , 光線力学療法 , がん , MRSA , 生体イメージング , 超分子 , 標的化診断・治療 , 薬剤耐性菌 , トランスレーショナルリサーチ , ドラッグデリバリーシステム , 高分子ミセル , 樹状細胞 , 近赤外レーザー , EPR効果 , インドシアニングリーン , ナノ材料創製 , 医用光・熱工学

Research theme for competitive and other funds (30)：

2021 - 2024 難治性リンパ管疾患に対する光温熱治療の開発
2021 - 2024 光温熱効果を利用した超分子デバイスによる胃癌腹膜播種に対する新規治療法
2021 - 2024 A New Photodynamic Therapy System for Deep Organ Cancer Using an Implantable Light-Emitting Device
2020 - 2024 脳内オピオイド産生の計測制御による過食のメカニズムの解明
2021 - 2023 Ultra-flexible light-emitting device for cancer treatment that attaches to deep organs and follows organ deformation

2018 - 2021 Novel therapeutic strategy against drug-resistant bacterial sepsis in compromised hosts focusing on enhancing bactericidal activity of macrophages

2018 - 2021 超低出力長時間光線力学療法を応用した転移進行癌に対する癌免疫治療

2018 - 2021 Photodynamic therapy for lymphangioma by using lymphatic fluid kinase.

2018 - 2021 Enhanced cellular engraftment of adipose-derived mesenchymal stem cell therapy by Nanosheets.

2018 - 2021 Effect of low-dose / low-dose-rate radiation on systemic immunity of disease model animals

2017 - 2020 Highly efficient cancer treatment system combined with a drug-delivery photoabsorbent agent and a tempreature-controled laser system

2017 - 2020 Anti-tumor activity in LPS tolerance and development of new technology on clinical application of tolerance

2016 - 2018 Can a natural amino acid be used for diagnosis and treatment for arteriosclerosis

2016 - 2018 Development of a next generation photothermal therapy using a light-absorbing drug that selectively accumulates in lesions for pediatric cancer

2015 - 2018 Photodynamic therapy using nanoparticle loaded with indocyanine green for experimental peritoneal dissemination of gastric cancer

2014 - 2018 Photo dynamic therapy for eradication of Helicobacter pylori

2015 - 2017 Refractory cancer treatment with photodynamic immunotherapy using implantable optical devices

2014 - 2017 Infection control based on photodynamic effect and new treatment for pressure ulcer by promoting wound healing

2013 - 2017 personally customized photodynamic therapy for oral cancer patients using porphyrin synthesis protein as a biomarker

2014 - 2016 Quantitative imaging of the target fluorescent substance by fluorescence multispectral endoscope

2013 - 2016 Management against surgical stress in compromised hosts

2013 - 2016 The establishment of photodynamic therapy(PDT) using 5-aminolevulinic acid (ALA) to the oral lichen planus

2012 - 2015 Photodynamic therapy using nanoparticle loaded with indocyanine green for experimental metastasis model of gastric cancer

2011 - 2015 Combination of indocyanine green and gold nano-particles for diagnosis and treatment of tumors and vascular abnormality

2011 - 2014 Development and biological evaluation of small molecule inhibitors for Met using a new strategy

2011 - 2014 Theranostic system for cancer by the combination of supramolecular nanocarriers with optical technology

2011 - 2012 Development of MR imaging technology and cell labeling contrast agents for tracking the biokinetics of dendritic cells.

2011 - 2012 Photodynamic diagnosis and treatment for local multiple-drug-resistant bacterial infection using photosensitizers that preferably accumulate into bacteria.

2010 - 2012 Indocyanine-green conjugated micelles for cancer theragnosis

2007 - 2008 Development of the therapeutic and diagnostic technology for vascular lesion using a complex of gold-nanospheres and indocyanine green

Show all

Papers (192)：

Akimasa Tashiro, David A Bereiter, Hiroyuki Ohta, Satoko Kawauchi, Shunichi Sato, Yuji Morimoto. Trigeminal sensitization in a closed head model for mild traumatic brain injury. Journal of neurotrauma. 2023
Manabu Harada, Yuji Morimoto, Ohara Mutsuki, Jun Ohya, Ken Masamune, Yujiro Itazaki, Takao Sugihara, Hironori Tsujimoto, Yoji Kishi, Hideki Ueno. Temperature-controlled laser thermal therapy system using a newly developed laparoscopic system equipped with an ultra-compact thermographic camera. Scientific Reports. 2022. 12. 1
Ryo Ishiwata, Yuji Morimoto. Hyperphosphatemia-induced degradation of transcription factor EB exacerbates vascular calcification. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2022. 1868. 3. 166323-166323
Masashi Arake, Hiroyuki Ohta, Aki Tsuruhara, Yasushi Kobayashi, Nariyoshi Shinomiya, Hiroaki Masaki, Yuji Morimoto. Measuring Task-Related Brain Activity With Event-Related Potentials in Dynamic Task Scenario With Immersive Virtual Reality Environment. Frontiers in Behavioral Neuroscience. 2022. 16
Kohsuke Hagisawa, Manabu Kinoshita, Shinji Takeoka, Osamu Ishida, Yayoi Ichiki, Daizoh Saitoh, Morihiro Hotta, Masato Takikawa, Ivo P Torres Filho, Yuji Morimoto. H12-(ADP)-liposomes for hemorrhagic shock in thrombocytopenia: Mesenteric artery injury model in rabbits. Research and practice in thrombosis and haemostasis. 2022. 6. 2. e12659

ｍore...

MISC (77)：

溝端裕亮, 戸田裕之, 古賀農人, 斉藤拓, 藤田真敬, 守本祐司. 脳細胞由来エクソソーム内包microRNAを用いた軽症うつ病の指標の探索. 防衛衛生. 2022. 69. 別冊. 29-29
太田宏之, 佐鳥玖仁郎, 宝田悠, 高橋達二, 荒毛将史, 守本祐司, 石塚俊晶. マウスの正と負の学習率の推定手法の提案~成功体験から学ぶのか,失敗体験から学ぶのか?~. 日本大脳基底核研究会. 2021. 35th (CD-ROM)
野村信介, 辻本広紀, 守本祐司. Direction for Development of Photothermal Therapy. Thermal Medicine. 2021. 37. 3
Hiroyuki Ohta, Arake Masashi, Satori Kuniaki, Takarada Yu, Takahashi Tatsuji, Satoh Yasushi, Morimoto Yuji, Ishizuka Toshiaki. Development of a five-armed bandit task for assessing behavioral flexibility. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2021. 94. 3-O-B2-2
Ryo Ishiwata, Yuji Morimoto. Transcription Factor EB Regulates Vascular Smooth Muscle Calcification. CIRCULATION. 2020. 142

ｍore...

Books (2)：

Photobiology: Principles, Applications and Effects
NOVA 2011
Photobiology: Principles, Applications and Effects
NOVA 2011

Lectures and oral presentations (222)：

脳細胞由来エクソソーム内包microRNAを用いた軽症うつ病の指標の探索
(防衛衛生 2022)
ラット肝細胞癌モデルを用いた腹腔鏡下光温熱治療の有用性に関する検討
(日本消化器外科学会総会 2021)
新規開発したサーモグラフィ内視鏡を用いたラット肝細胞癌に対する鏡視下レーザーアブレーション治療
(日本外科学会定期学術集会抄録集 2021)
ラット肝細胞癌モデルにおける光温熱治療の効果的なエネルギー照射の検討
(日本消化器外科学会総会 2020)
消化管間葉系腫瘍リアルタイムイメージングのための近赤外蛍光色素の開発
(日本外科学会定期学術集会抄録集 2020)

ｍore...

Professional career (1)：

MD (Ph. D)

Work history (9)：

2018/04 - 現在 National Defense Medical College Department of Physiology Professor
2007 - 防衛医科大学校分子生体制御学講座准教授
2001 - 防衛医科大学校医用電子工学講座助手
2000 - 名古屋市立大学医学部生理学第一講座客員研究員
1999 - 陸上自衛隊第十師団医務官

Show all

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page