Rchr
J-GLOBAL ID：201301088158443843   Update date: Feb. 01, 2024

Kon Shunsuke

コン シユンスケ | Kon Shunsuke
Affiliation and department：
Tokyo University of Science Organization for Research Advancement, Research Institute for Biomedical Sciences, Research Division

About Tokyo University of Science Organization for Research Advancement, Research Institute for Biomedical Sciences, Research Division


Job title： Junior Associate Professor
Homepage URL  (1)： https://konshunsukelab.wixsite.com/rs-tus
Research field  (1)： Tumor biology
Research keywords  (3)： tumor-induced lymphangiogenesis ,  cell competition ,  tumorigenesis
Research theme for competitive and other funds  (13)：
  • 2021 - 2023 Singularity at emergence of cancer cells in normal stroma
  • 2020 - 2023 Molecular dissection of malfunction of cell competition-mediated elimination of transformed cells in intestine
  • 2020 - 2022 Delineation of the tumor-suppressive autophagy mode through cell competition
  • 2018 - 2022 Structural analysis of tumor hotspots, an epithelial tissue-intrinsic novel oncogenic niche
  • 2019 - 2021 singularity in normal stroma at emergence of cancer cells
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Papers (32)：
  • Takanobu Shirai, Miho Sekai, Kei Kozawa, Nanami Sato, Nobuyuki Tanimura, Shunsuke Kon, Tomohiro Matsumoto, Takeru Murakami, Shoko Ito, Andrew Tilston-Lunel, et al. Basal extrusion of single-oncogenic mutant cells induces dome-like structures with altered microenvironments. Cancer Science. 2022. 113. 11. 3710-3721
  • Eilma Akter, Yukihiro Tasaki, Yusuke Mori, Kazuki Nakai, Kazuki Hachiya, Hancheng Lin, Masamitsu Konno, Tomoko Kamasaki, Kenji Tanabe, Yumi Umeda, et al. Non-degradable autophagic vacuoles are indispensable for cell competition. Cell Reports. 2022. 40. 9. 111292-111292
  • Nanase Igarashi, Kenichi Miyata, Tze Mun Loo, Masatomo Chiba, Aki Hanyu, Mika Nishio, Hiroko Kawasaki, Hao Zheng, Shinya Toyokuni, Shunsuke Kon, et al. Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells. Nature communications. 2022. 13. 1. 4157-4157
  • Yusuke Mori, Naoka Shiratsuchi, Nanami Sato, Azusa Chaya, Nobuyuki Tanimura, Susumu Ishikawa, Mugihiko Kato, Ikumi Kameda, Shunsuke Kon, Yukinari Haraoka, et al. Extracellular ATP facilitates cell extrusion from epithelial layers mediated by cell competition or apoptosis. Current Biology. 2022. 32. 10. 2144-2159.e5
  • S. Kon and Y. Fujita. Cell competition-induced apical elimination of transformed cells, EDAC, orchestrates the cellular homeostasis. DEVELOPMENTAL BIOLOGY. 2021. 476. 112-116
ｍore...
MISC (4)：
Books (8)：
  • サイエンスへの招待 「がんを早期のうちに退治する」
    理大 科学フォーラム 2021
  • 2019年度ノーベル賞 生理学・医学賞 「低酸素応答の仕組み」
    理大 科学フォーラム 2020
  • ワールブルグ効果様代謝変化による抗腫瘍機能
    生化学 2018
  • 細胞競合とがんの代謝
    実験医学 2017
  • 正常な上皮細胞はがん変異細胞にWarburg効果様の代謝の変化を引き起こし上皮層から排除する
    ライフサイエンス 新着論文レビュー 2017
ｍore...
Lectures and oral presentations  (32)：
  • がん細胞が誕生したときの生体内反応
    (フォーラム富山「創薬」 第53回研究会 2021)
  • 若手融合がもたらすがん研究ブレークスルー
    (第79回 日本癌学会 2020)
  • Singularity at emergence of cancer cells in normal stroma
    (第58回 日本生物物理学会 2020)
  • がん細胞が出現した正常間質組織でのシンギュラリティ現象の解明
    (新学術領域研究「シンギュラリティ生物学」,「細胞ダイバース」合同会議 2020)
  • 細胞競合と発がん
    (第3回がんと代謝研究会・若手の会 2019)
ｍore...
Education (4)：
  • - 2008 Tohoku University Graduate School of Life Sciences
  • - 2008 Tohoku University Graduate School of Life Sciences
  • - 2003 Tohoku University Faculty of Engineering Department of Applied Chemistry, Chemical Engineering and Biomolecular Engineering
  • - 2003 Tohoku University Faculty of Engineering Department of Applied Chemistry, Chemical Engineering and Biomolecular Engineering
Professional career (1)：
  • Ph.D. (Life Science) (Tohoku University)
Work history (5)：
  • 2018/04 - 現在 Tokyo University of Science Organization for Research Advancement Research Institute for Biomedical Science
  • 2017/07 - 2018/03 Hokkaido University, Institute for Genetic Medicine Division of Molecular Oncology Junior Associate Professor
  • 2013/07 - 2017/06 Hokkaido University, Institute for Genetic Medicine Division of Molecular Oncology Assistant Professor
  • 2009/04 - 2013/06 Tohoku University, Institute of Development, Aging and Cancer Division of Molecular Immunology Assistant Professor
  • 2008/04 - 2009/03 Tohoku University, Institute of Development, Aging and Cancer Division of Molecular Immunology Post doctoral fellow
Committee career (1)：
  • 2019/06/24 - 2019/06/24 日本細胞生物学会 第71回 日本細胞生物学会 若手最優秀発表賞 選考委員
Awards (5)：
  • 2018/05/25 - Best Articles of the Year
  • 2018/03/03 - 血管生物医学若手最優秀賞
  • 2017/06/14 - 日本細胞生物学会若手最優秀賞
  • 2014/09/06 - がん若手ワークッショップ最優秀演者賞
  • 2014/01/17 - 東北大学加齢医学研究所研究奨励賞
Association Membership(s) (3)：
日本分子生物学会 ,  日本癌学会 ,  日本細胞生物学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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