Rchr
J-GLOBAL ID:201401003404681718   Update date: Feb. 01, 2024

Nakaoka Hirofumi

ナカオカ ヒロフミ | Nakaoka Hirofumi
Affiliation and department:
Job title: 部長
Research field  (2): Medical biochemistry ,  Genomics
Research theme for competitive and other funds  (10):
  • 2023 - 2027 Gene-environment interactions inducing spatial expansion of mutant clones in human normal tissues
  • 2022 - 2025 Identification of the significance of cancer-associated gene mutations in normal endometrium
  • 2021 - 2024 Longitudinal analysis of IGF1 gene methylation in preterm infants
  • 2020 - 2023 Molecular characterization of normal endometrial epithelial cells with cancer-associated gene mutations
  • 2019 - 2021 Approach to regulatory mechanism of copy number variation the gene amplified.
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Papers (118):
  • Hidehiko Akashi, Nozomi Yachida, Haruka Ueda, Manako Yamaguchi, Kaoru Yamawaki, Ryo Tamura, Kazuaki Suda, Tatsuya Ishiguro, Sosuke Adachi, Yoshikazu Nagase, et al. SLFN11 is a BRCA independent biomarker for the response to platinum-based chemotherapy in high-grade serous ovarian cancer and clear cell ovarian carcinoma. Molecular cancer therapeutics. 2023
  • Ryo Tamura, Hirofumi Nakaoka, Nozomi Yachida, Haruka Ueda, Tatsuya Ishiguro, Teiichi Motoyama, Ituro Inoue, Takayuki Enomoto, Kosuke Yoshihara. Spatial genomic diversity associated with APOBEC mutagenesis in squamous cell carcinoma arising from ovarian teratoma. Cancer science. 2023. 114. 5. 2145-2157
  • Detecting and Quantifying Donor derived cell free DNA in the blood of kidney transplant recipients as a biomarker for graft injury and immunosuppression. Organ Biology. 2023. 30. 1. 7-14
  • Yu Toyoda, Masahiro Nakatochi, Akiyoshi Nakayama, Yusuke Kawamura, Hirofumi Nakaoka, Kenji Wakai, Keitaro Matsuo, Hirotaka Matsuo. SNP-based heritability estimates of gout and its subtypes determined by genome-wide association studies of clinically defined gout. Rheumatology (Oxford, England). 2022
  • Sundaramoorthy Revathidevi, Kazuyoshi Hosomichi, Toyoaki Natsume, Hirofumi Nakaoka, Naoko T. Fujito, Hisako Akatsuka, Takehito Sato, Arasambattu Kannan Munirajan, Ituro Inoue. AMBRA1 p.Gln30Arg Mutation, Identified in a Cowden Syndrome Family, Exhibits Hyperproliferative Potential in hTERT-RPE1 Cells. International Journal of Molecular Sciences. 2022. 23. 19. 11124-11124
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MISC (12):
  • Hirotaka Matsuo, Toshihide Higashino, Tappei Takada, Hirofumi Nakaoka, Yu Toyoda, Blanka Stiburkova, Hiroshi Nakashima, Seiko Shimizu, Makoto Kawaguchi, Akiyoshi Nakayama, et al. Comprehensive Association Analysis between Rare and Common ABCG2 Variants and Gout Susceptibility. ARTHRITIS & RHEUMATOLOGY. 2018. 70
  • Higashino T, Takada T, Nakaoka H, Toyoda Y, Stiburkova B, Wakai K, Ooyama H, Inoue I, Merriman T. R, Shinomiya N, et al. COMPREHENSIVE EVALUATION OF THE EFFECTS OF RARE AND COMMON EXONIC ABCG2 VARIANTS ON GOUT SUSCEPTIBILITY. ANNALS OF THE RHEUMATIC DISEASES. 2018. 77. 230-231
  • Yuki Matsumoto, Tatsuhiko Goto, Hirofumi Nakaoka, Jo Nishino, Akira Tanave, Richard F. Mott, Tsuyoshi Koide. Wild-derived heterogeneous stock mice to find the loci associated with tame behavior. GENES & GENETIC SYSTEMS. 2014. 89. 6. 314-314
  • 芳賀 秀郷, 山口 徹太郎, 中岡 博史, 佐本 博, 井ノ上 逸朗, 槇 宏太郎. 第三大臼歯欠如をもたらす遺伝因子の探索. 東京矯正歯科学会雑誌. 2013. 23. 2. 119-119
  • 芳賀 秀郷, 山口 徹太郎, 中岡 博史, 佐本 博, 大野 粛英, 井ノ上 逸朗, 槇 宏太郎. ゲノムワイド関連解析から同定される第三大臼歯欠如をもたらす遺伝要因の探索. 日本矯正歯科学会大会プログラム・抄録集. 2013. 72回. 286-286
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Education (2):
  • 2003 - 2008 Kyoto University Graduate School of Agriculture
  • 1999 - 2003 Kyoto University Faculty of Agriculture
Professional career (1):
  • Ph.D. (Kyoto University)
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