Rchr
J-GLOBAL ID:201401003434622058   Update date: Apr. 12, 2024

Fukushima Yuji

Fukushima Yuji
Affiliation and department:
Research field  (3): Immunology ,  Neuropathology ,  Tumor biology
Research keywords  (4): 免疫老化 ,  自己免疫 ,  がん ,  中枢神経
Research theme for competitive and other funds  (5):
  • 2024 - 2028 加齢変容性リンパ球が介在する多発性硬化症の病態機序解明とその制御
  • 2022 - 2025 非定型TCR複合体を形成する機能不全耐性T細胞集団の作出とがん治療への応用
  • 2022 - 免疫老化関連分子を活用した免疫監視機構の人為的強化
  • 2017 - 2020 Control of senescence-associated T cell-induction
  • 2014 - 2017 Study on the mechanism(s) of immunosenescence and its application for vaccine development.
Papers (12):
  • Yuji Fukushima, Nagahiro Minato, Masakazu Hattori. Protocol for the isolation of mouse senescence-associated CD4+ T cells using flow cytometry and functional assays. STAR protocols. 2023. 4. 3. 102472-102472
  • Yuji Fukushima, Keiko Sakamoto, Michiyuki Matsuda, Yasunobu Yoshikai, Hideo Yagita, Daisuke Kitamura, Misaki Chihara, Nagahiro Minato, Masakazu Hattori. cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells. Cell reports. 2022. 40. 12. 111373-111373
  • Yuki Sato, Akiko Oguchi, Yuji Fukushima, Kyoko Masuda, Naoya Toriu, Keisuke Taniguchi, Takahisa Yoshikawa, Xiaotong Cui, Makiko Kondo, Takeshi Hosoi, et al. CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury. The Journal of clinical investigation. 2022. 132. 2
  • Fukushima Y, Minato N, Hattori M. The impact of senescence-associated T cells on immunosenescence and age-related disorders. Inflammation and regeneration. 2018. 38. 24-24
  • Koyu Ito, Akira Nakajima, Yuji Fukushima, Keiichiro Suzuki, Keiko Sakamoto, Yoko Hamazaki, Kouetsu Ogasawara, Nagahiro Minato, Masakazu Hattori. The potential role of Osteopontin in the maintenance of commensal bacteria homeostasis in the intestine. PloS one. 2017. 12. 3. e0173629
more...
MISC (1):
  • 福島 祐二, 服部 雅一. T細胞の加齢変化と老化関連T細胞の病理学的関与. 臨床免疫・アレルギー科. 2023. 79. 1. 8-14
Lectures and oral presentations  (3):
  • Senescence-associated CD4+ T cells and Autoimmune Pathology
    (The 52nd Annual Meeting of The Japanese Society for Immunology, International Symposium, DGFI-JSI Joint Session "Humoral Immunity" 2024)
  • 老化関連T細胞と自己免疫疾患
    (第51回 日本臨床免疫学会総会 シンポジウム 2023)
  • CD153-CD30 interaction is involved in immunosenescence of T cells and spontaneous germinal center reactions
    (第45回 日本免疫学会学術集会 2016)
Work history (3):
  • 2018/04 - 現在 京都大学 医学研究科 特定助教
  • 2011/04 - 2017/03 京都大学 医学研究科 研究員
  • 2010/04 - 2011/03 広島大学 生物圏科学研究科 特任助教
Association Membership(s) (2):
日本免疫学会 ,  日本分子生物学会
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