YAMAGUCHI Yoshihiro

ヤマグチヨシヒロ | YAMAGUCHI Yoshihiro

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://www.omu.ac.jp/sci/biol-mbiol/

Research field (2)： Molecular biology , Applied microbiology

Research keywords (4)： programmed cell death , bacteria , mRNA interference , toxin antitoxin system

Research theme for competitive and other funds (10)：

2021 - 2025 分散接着性大腸菌による腸炎抑制メカニズム解明とプロバイオティクスへの応用
2021 - 2024 大腸菌の新規 yafD-yafE TA system の機能同定
2018 - 2021 Mechanism of biofilm formation and cell death mediated with MqsA in Escherichia coli
2017 - 2020 Validation on the possible zoonotic transmission by a novel colonization factor found on pandemic enterotoxigenic E. coli serogroup O169
2017 - 2019 細菌の休眠及び覚醒を制御する HipA、YjjJ と HipB の相互作用

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Papers (66)：

Ilhamzah, Tsukuda Y, Yamaguchi Y, Ogita A, Fujita KI. Persimmon tannin promotes the growth of Saccharomyces cerevisiae under ethanol stress. Journal of the science of food and agriculture. 2024
Yamano S, Tsukuda Y, Mizuhara N, Yamaguchi Y, Ogita A, Fujita KI. Dehydrozingerone enhances the fungicidal activity of glabridin against Saccharomyces cerevisiae and Candida albicans. Letters in applied microbiology. 2023. 76. 4
Kato F, Yamaguchi Y, Inouye K, Matsuo K, Ishida Y, Inouye M. A novel gyrase inhibitor from toxin-antitoxin system expressed by Staphylococcus aureus. The FEBS journal. 2023. 290. 6. 1502-1518
Bonini AA, Maggi S, Mori G, Carnuccio D, Delfino D, Cavazzini D, Ferrari A, Levante A, Yamaguchi Y, Rivetti C, et al. Functional characterization and transcriptional repression by Lacticaseibacillus paracasei DinJ-YafQ. Applied microbiology and biotechnology. 2022. 106. 21. 7113-7128
Y Tsukuda, N Mizuhara, Y Usuki, Y Yamaguchi, A Ogita, T Tanaka, K Fujita. Structure-activity relationships of antifungal phenylpropanoid derivatives and their synergy with n-dodecanol and fluconazole. Letters in applied microbiology. 2022. 74. 3. 377-384

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MISC (20)：

Ogita Akira, Fujita Ken-ichi, Yamaguchi Yoshihiro, Yamauchi Ken, Tanaka Toshio. 3P-271 Enhancement of antimicrobial activity of parabens by sulforaphane, an isothiocyanate from broccoli. 2015. 67. 338-338
Yamaguchi Y. Regulation of recognition and degradation of sequence-specific mRNA interferases. Seibutsu Butsuri. 2015. 55. 1. 011-014
Jung-Ho Park, Yoshihiro Yamaguchi, Masayori Inouye. Suppression of MazF toxicity by fusing a C-terminal segment of MazE to MazF, and its activation by sequence specific HIV-1 and HCV proteases. FASEB JOURNAL. 2012. 26
薮野佑介, 薮野佑介, 加藤文紀, 菅井基行, 井上正順, 山口良弘. ブドウ球菌Toxin-Antitoxin system MazEFの解析. 日本細菌学雑誌. 2012. 67. 1. 168
神尾好是, 山口良弘, 高塚由美子. ポリアミン結合型細胞壁をもつ細菌とその真核生物型ポリアミン合成制御機構. 蛋白質核酸酵素. 2007. 52. 3. 249-255

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Patents (1)：

Books (3)：

Toxin-Antitoxin Systems in Bacteria and Archaea
Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria, Willy 2016 ISBN:9781119004882
Polyamines: A Universal Molecular Nexus for Growth, Survival, and Specialized Metabolism
Springer 2015 ISBN:4431552111
Prokaryotic Toxin-Antitoxins
Springer 2012 ISBN:3642332528

Lectures and oral presentations (127)：

出芽酵母における微小管重合阻害剤添加細胞のミトコンドリアの融合・分裂異常
(日本生物工学会大会講演要旨集 2023)
ショウガ辛味成分6-shogaolとエタノールの併用による抗真菌効果とその作用機序
(日本生物工学会大会講演要旨集 2023)
DNAジャイレース阻害剤、Staphylococcus aureusが発現するTsbT(DNA gyrase inhibitor, TsbT expressed by Staphylococcus aureus)
(日本細菌学雑誌 2023)
高度好塩菌Halomicrobium mukohataeiのMazFの機能解析
(日本生物工学会大会講演要旨集 2022)
出芽酵母における微小管重合阻害とミトコンドリアの融合・分裂異常の関係
(日本生物工学会大会講演要旨集 2022)

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Education (3)：

Professional career (1)：

Work history (4)：

2022/04 - 現在 Osaka Metropolitan University School of Science Department of Biology Associate Professor
2010 - 2014 Robert Wood Johnson Medical School Department of Biochemistry Research and teaching stuff III
2006 - 2010 Robert Wood Johnson Medical School Department of Biochemistry Postdoctoral fellow
1999/04 - 2000/03 東北大学農学部研究生

Awards (2)：

2012 - Dean’s research awards for the best peer-reviewed publications of 2012 Inhibition of specific gene expressions by protein-mediated mRNA interference
2002 - Japan Society for Bioscience, Biotechnology, and Agrochemistry Award for Excellence to Authors Publishing in Bioscience Biotechnology and Biochemistry

Association Membership(s) (4)：

日本生化学会 , 日本生物工学会 , 日本細菌学会 , 日本農芸化学会

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