Kouichi Matsuda

Matsuda Koichi | Kouichi Matsuda

Affiliation and department：
Job title：教授
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/90401257.ja.html

Research field (5)： Genomics , Tumor diagnostics and therapeutics , Cell biology , Gastroenterology , Urology

Research keywords (9)： bone and soft tissue tumor , biobank , p53 , ゲノムワイド関連解析 , 遺伝子多型 , 細胞老化 , バイオマーカー , 癌抑制遺伝子 , シトルリン化

Research theme for competitive and other funds (20)：

2022 - 2025 骨軟部腫瘍全ゲノム解析データに基づく遺伝子異常の機能解析と治療標的の同定
2020 - 2025 Development of personalized soft tissue sarcoma therapies through the integrated genomic analysis
2021 - 2024 本邦における脳梗塞関連遺伝子座と臨床的特徴に関する検討
2018 - 2023 希少がんである脊索腫における腫瘍原生並びに治療標的となるゲノム変異の探索
2019 - 2022 Identification of functional variants by comprehensive analysis of coding variants for the implementation of genomic medicine

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Papers (336)：

Markus Scholz, Katrin Horn, Janne Pott, Matthias Wuttke, Andreas Kühnapfel, M. Kamal Nasr, Holger Kirsten, Yong Li, Anselm Hoppmann, Mathias Gorski, et al. X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements. Nature Communications. 2024. 15. 1
Amy Hui Ping Khor, Tomoyuki Koguchi, Hao Liu, Masanori Kakuta, Daisuke Matsubara, Ruimeng Wen, Yoji Sagiya, Seiya Imoto, Hidewaki Nakagawa, Koichi Matsuda, et al. Regulation of the innate immune response and gut microbiome by p53. Cancer science. 2023
Anqi Wang, Jiayi Shen, Alex A. Rodriguez, Edward J. Saunders, Fei Chen, Rohini Janivara, Burcu F. Darst, Xin Sheng, Yili Xu, Alisha J. Chou, et al. Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants. Nature Genetics. 2023. 55. 12. 2065-2074
Zhishan Chen, Weiqiang Lin, Qiuyin Cai, Sun-Seog Kweon, Xiao-Ou Shu, Chizu Tanikawa, Wei-Hua Jia, Ying Wang, Xinwan Su, Yuan Yuan, et al. A large-scale microRNA transcriptome-wide association study identifies two susceptibility microRNAs, miR-1307-5p and miR-192-3p, for colorectal cancer risk. Human molecular genetics. 2023
Shuji Ito, Xiaoxi Liu, Yuki Ishikawa, David D Conti, Nao Otomo, Zsofia Kote-Jarai, Hiroyuki Suetsugu, Rosalind A Eeles, Yoshinao Koike, Keiko Hikino, et al. Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects. Nature communications. 2023. 14. 1. 4863-4863

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MISC (61)：

Mingyang Shi, Chizu Tanikawa, Hans Markus Munter, Masato Akiyama, Satoshi Koyama, Kohei Tomizuka, Koichi Matsuda, Gregory Mark Lathrop, Chikashi Terao, Masaru Koido, et al. Characterizing the quality metric in genotype imputation. bioRxiv. 2023
Yunye He, Masaru Koido, Yoichi Sutoh, Mingyang Shi, Yayoi Otsuka-Yamasaki, Hans Markus Munter, Takayuki Morisaki, Akiko Nagai, Yoshinori Murakami, Chizu Tanikawa, et al. East Asian-specific and cross-ancestry genome-wide meta-analyses provide mechanistic insights into peptic ulcer disease. medRxiv. 2022
Yoshinori Murakami, Koichi Matsuda, Takayuki Morisaki, Yukihide Momozawa, Toshiki Watanabe, Yataro Daigo, Kenji Wakai. Cohorts and biobanks as essential resources for accelerating precision medicine in cancer. CANCER SCIENCE. 2021. 112. 1013-1013
小西惇, 山下享子, 角田達彦, 鎌谷高志, 松田浩一, 平田真, 植田幸嗣. 網羅的プロテオーム解析による粘液型脂肪肉腫の予後不良因子の探索. 日本癌学会総会記事. 2020. 79回. OE14-4
Saori Sakaue, Masahiro Kanai, Juha Karjalainen, Masato Akiyama, Mitja Kurki, Nana Matoba, Atsushi Takahashi, Makoto Hirata, Michiaki Kubo, Koichi Matsuda, et al. Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan. Nature medicine. 2020. 26. 4. 542-548

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Professional career (1)：

医学博士 (東京大学)

Work history (3)：

2016/07 - 現在 The University of Tokyo Graduate School of Frontier Sciences
2010 - 2016/06 The University of Tokyo The Institute of Medical Science
2004/06 - 2010 東京大学医科学研究所助教

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