Rchr
J-GLOBAL ID:201401013012592828   Update date: Feb. 01, 2024

Yoshida Kenichi

ヨシダ ケンイチ | Yoshida Kenichi
Affiliation and department:
Job title: Chief
Research field  (3): Fetal medicine/Pediatrics ,  Hematology and oncology ,  Tumor biology
Research theme for competitive and other funds  (10):
  • 2022 - 2025 前がん病変の空間的ゲノム、発現解析による肺腺がん多段階発がん機構の解明
  • 2022 - 2024 Study of somatic mutations in normal blood cells using whole-genome sequencing
  • 2016 - 2022 大規模シーケンス解析に基づく、造血器腫瘍のゲノム、エピゲノムにおける、空間的・時間的多様性の研究
  • 2016 - 2021 Development of molecular targeted therapy for primary central nervous system lymphomas
  • 2015 - 2020 Computational reconstruction of the higher-order structure of chromosomes and linkage analysis between chromosome structure and phenotype
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Papers (226):
  • Daniel Noerenberg, Franziska Briest, Cornelius Hennch, Kenichi Yoshida, Raphael Hablesreiter, Yasuhide Takeuchi, Hiroo Ueno, Annette M Staiger, Marita Ziepert, Fazila Asmar, et al. Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2023. JCO2301053
  • Takahiro Aoki, Norio Shiba, Shinichi Tsujimoto, Genki Yamato, Yusuke Hara, Shota Kato, Kenichi Yoshida, Seishi Ogawa, Yasuhide Hayashi, Shotaro Iwamoto, et al. High IL2RA/CD25 expression is a prognostic stem cell biomarker for pediatric acute myeloid leukemia without a core-binding factor. Pediatric blood & cancer. 2023. e30803
  • Yusuke Hara, Norio Shiba, Kenichi Yoshida, Genki Yamato, Taeko Kaburagi, Yuichi Shiraishi, Kentaro Ohki, Yusuke Shiozawa, Machiko Kawamura, Hirohide Kawasaki, et al. TP53 and RB1 alterations characterize poor prognostic subgroups in pediatric acute myeloid leukemia. Genes, chromosomes & cancer. 2023. 62. 7. 412-422
  • Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia Claire Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steven Best, Pramila Krishnamurthy, Tetsuichi Yoshizato, et al. Germline DDX41 mutations define a unique subtype of myeloid neoplasms. Blood. 2022. 141. 5. 534-549
  • Kentaro Watanabe, Shunsuke Kimura, Masafumi Seki, Tomoya Isobe, Yasuo Kubota, Masahiro Sekiguchi, Aiko Sato-Otsubo, Mitsuteru Hiwatari, Motohiro Kato, Akira Oka, et al. Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism. Oncogene. 2022. 41. 46. 4994-5007
more...
MISC (112):
  • Genki Yamato, Tomoko Kawai, Norio Shiba, Yusuke Hara, Kentaro Ohki, Taeko Kaburagi, Etsuko Ishikita, Hirohide Kawasaki, Kenichi Yoshida, Yuichi Shiraishi, et al. Prognosis of Pediatric Acute Myeloid Leukemia with KMT2A-MLLT3 According to DNA Methylation Patterns: Jccg JPLSG AML-05 Study. BLOOD. 2022. 140. 9134-9135
  • June Takeda, Kenichi Yoshida, Masahiro M. Nakagawa, Yasuhito Nannya, Akinori Yoda, Ryunosuke Saiki, Yotaro Ochi, Lanying Zhao, Rurika Okuda, Xingxing Qi, et al. Amplified EPOR/JAK2 genes definea unique subtype of acute erythroid leukemia. CANCER RESEARCH. 2022. 82. 12
  • Tomomi Nishimura, Nobuyuki Kakiuchi, Kenichi Yoshida, Yasuhide Takeuchi, Hirona Maeda, Yusuke Shiozawa, Masahiro Hirata, Tatsuki R. Kataoka, Takaki Sakurai, Satoko Baba, et al. Clonal evolution of proliferative lesions into breast cancers. CANCER SCIENCE. 2021. 112. 157-157
  • Yotaro Ochi, Kenichi Yoshida, Ko Sasaki, Noriko Hosoya, Yusuke Shiozawa, Yasuhito Nannya, Takayuki Ishikawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, et al. Genetic profiling and prognosis of blast crisis in chronic myeloid leukemia. CANCER SCIENCE. 2021. 112. 454-454
  • Yasuhide Takeuchi, Hiromichi Suzuki, Kenichi Yoshida, Yuichi Shiraishi, Nobuyuki Kakiuchi, Yusuke Shiozawa, Yoshikage Inoue, Kenichi Chiba, Hideki Makishima, Satoru Miyano, et al. Frequent abnormalities in TP53 and increased genetic instability in myxofibrosarcoma. CANCER SCIENCE. 2021. 112. 850-850
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Lectures and oral presentations  (57):
  • 正常組織にみられる体細胞性変異の解析によるがんの病態の理解
    (第81回日本癌学会学術総会 2022)
  • 小児がんの発症時ゲノム検索の意義
    (第125回日本小児科学会学術集会 2022)
  • Somatic mutations in normal bronchial epithelia.
    (1st JCA-AACR Precision Cancer Medicine International Conference 2021)
  • Genetic analysis of somatic mutations in normal tissues using whole-genome sequencing.
    (第61回日本呼吸器学会学術講演会 2021)
  • Somatic mutations in normal bronchial epithelia involved in lung carcinogenesis.
    (第79回日本癌学会学術総会 2020)
more...
Education (2):
  • 2010 - 2014 The University of Tokyo Graduate School of Medicine
  • 1999 - 2005 Tohoku University Faculty of Medicine
Professional career (1):
  • Doctor of Philosophy (The University of Tokyo)
Work history (8):
  • 2022/04 - 現在 National Cancer Center Research Institute Division of Cancer Evolution Chief
  • 2020/03 - 2022/03 Wellcome Sanger Institute Postdoctoral fellow
  • 2018/02 - 2020/02 Overseas Research Fellowship, Japan Society for the Promotion of Science
  • 2014/09 - 2018/02 Graduate School of Medicine, Kyoto University Department of Pathology and Tumor Biology Assistant Professor
  • 2014/04 - 2014/08 Graduate School of Medicine, Kyoto University Department of Pathology and Tumor Biology Program-Specific Assistant Professor
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Awards (5):
  • 2021/04 - Kiyoko Goto and Paul Bourdarie Cancer Foundation The 9th (2020) Kiyoko and Paul Bourdarie-Goto Scientific Prize Tobacco smoking and somatic mutations in human bronchial epithelium
  • 2014/09 - Japanese Cancer Association Incitement Award of the Japanese Cancer Association
  • 2014/02 - Nagoya International Cancer Treatment Symposium BMS Award in Nagoya Symposium Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia
  • 2012/11 - The Japanese Society of Pediatric Hematology / Oncology Prize for Science from The Japanese Society of Pediatric Hematology/Oncology
  • 2011/10 - The Japanese Society of Hematology Incitement Award of the Japanese Society of Hematology
Association Membership(s) (7):
American Association for Cancer Research ,  American Society of Hematology ,  European Hematology Association ,  Japanese Society of Hematology ,  Japanese Cancer Association ,  Japanese Society of Pediatric Hematology/Oncology ,  Japan Pediatric Society
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