Rchr
J-GLOBAL ID:201401019589926391   Update date: Jan. 31, 2024

Morita Daisuke

Morita Daisuke
Affiliation and department:
Research field  (1): Immunology
Research theme for competitive and other funds  (5):
  • 2021 - 2024 「リポペプチド免疫」に着目した自己免疫の新機軸
  • 2018 - 2021 Novel strategy of host defense targeted for "viral lipopeptides"
  • 2016 - 2018 Identification and functional analysis of a novel class of human MHC class I molecules presenting lipopeptide antigens
  • 2014 - 2016 Crystallographic analysis of the MHC class I:lipopeptide complex and identification of the lipopepitide-angigen presentation pathway
  • 2013 - 2015 「リポペプチド」を提示するMHCクラスI分子の同定とその免疫機能解析
Papers (23):
  • Daisuke Morita, Minori Asa, Masahiko Sugita. Engagement with the TCR induces plasticity in antigenic ligands bound to MHC class I and CD1 molecules. International immunology. 2023. 35. 1. 7-17
  • Tatsuaki Mizutani, Toshiaki Ano, Yuya Yoshioka, Satoshi Mizuta, Keiko Takemoto, Yuki Ouchi, Daisuke Morita, Satsuki Kitano, Hitoshi Miyachi, Tatsuaki Tsuruyama, et al. Neutrophil S100A9 supports M2 macrophage niche formation in granulomas. iScience. 2023. 106081-106081
  • Asa Minori, Morita Daisuke, Sugita Masahiko. T Cell activation and responses(human and Vitro)(Dynamic B-pocket remodeling is a basis for HLA class I molecules to bind peptides and lipopeptides). 日本免疫学会総会・学術集会記録. 2022. 51. Proceedings. WS26-O/P
  • Minori Asa, Daisuke Morita, Jin Kuroha, Tatsuaki Mizutani, Naoki Mori, Bunzo Mikami, Masahiko Sugita. Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding. Journal of Biological Chemistry. 2022. 298. 7. 102100-102100
  • Daisuke Morita, Chieri Iwashita, Tatsuaki Mizutani, Naoki Mori, Bunzo Mikami, Masahiko Sugita. Crystal structure of the ternary complex of TCR, MHC class I, and lipopeptides. International immunology. 2020. 32. 12. 805-810
more...
MISC (12):
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Lectures and oral presentations  (9):
  • T-cell recognition of the lipopeptide-bound MHC class I complex; evidence from the crystal structure
    (The 15th International Symposium of the Institute Network for Biomedical Sciences 2020 2020)
  • 霊長類研究から見えてきた、非ペプチド抗原を標的とする新しい獲得免疫機構
    (第29回 日本生体防御学会学術総会 2018)
  • 霊長類研究から見えてきた、「非ペプチド」抗原を標的とする新しい免疫システムの解明
    (ForteBioセミナーin大阪 2018 2018)
  • Lipopeptide: a novel immune target for viral infection
    (2018)
  • Discovery of N-myristoylated lipopeptide Ag-presenting MHC class I molecules
    (East Asia Joint Symposium 2016)
more...
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