Sato Keita

サトウケイタ | Sato Keita

Affiliation and department：
Homepage URL (1)： https://twitter.com/KeitasatoAtwork

Research field (1)： Animals: biochemistry, physiology, behavioral science

Research keywords (5)： non-visual photoreception , Optogenetics , Vision , Rhodopsin , 光生物学

Research theme for competitive and other funds (9)：

2023 - 2026 魚類眼外組織光受容系の分子・細胞・神経機構の解明
2021 - 2023 光駆動Gタンパク質共役型受容体を基盤とした生命現象の光操作
2022 - 2023 モデル魚類を用いた網膜変性疾患の研究
2020 - 2023 Molecular mechanism of photoreception in the fish pituitary
2020 - 2023 眼球伸長におけるFGF10と紫光Opsin5システムの機能解明

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Papers (24)：

Keita Sato, Takahiro Yamashita, Hideyo Ohuchi. Mammalian type Opsin 5 preferentially activates G14 in Gq-type G proteins triggering intracellular calcium response. The Journal of biological chemistry. 2023. 105020-105020
Chihiro Fujiyabu, Keita Sato, Hideyo Ohuchi, Takahiro Yamashita. Diversification processes of teleost intron-less opsin genes. The Journal of biological chemistry. 2023. 104899-104899
Misao Mizuno, Keita Sato, Takahiro Yamashita, Kazumi Sakai, Yasushi Imamoto, Yumiko Yamano, Akimori Wada, Hideyo Ohuchi, Yoshinori Shichida, Yasuhisa Mizutani. Chromophore Structure in an Inactive State of a Novel Photosensor Protein Opn5L1: Resonance Raman Evidence for the Formation of a Deprotonated Adduct at the 11th Carbon Atom. The journal of physical chemistry. B. 2023. 127. 10. 2169-2176
Keita Sato, Yang Liu, Takahiro Yamashita, Hideyo Ohuchi. The medaka mutant deficient in eyes shut homolog exhibits opsin transport defects and enhanced autophagy in retinal photoreceptors. Cell and tissue research. 2022
Yuki Kanzaki, Hirofumi Fujita, Keita Sato, Mio Hosokawa, Hiroshi Matsumae, Yuki Morizane, Hideyo Ohuchi. Protrusion of KCNJ13 Gene Knockout Retinal Pigment Epithelium Due to Oxidative Stress-Induced Cell Death. Investigative ophthalmology & visual science. 2022. 63. 12. 29-29

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MISC (3)：

Keita Sato, Hideyo Ohuchi. Molecular Property, Manipulation, and Potential Use of Opn5 and Its Homologs. Journal of molecular biology. 2023. 168319-168319
Hideyo Ohuchi, Keita Sato, Munenori Habuta, Hirofumi Fujita, Tetsuya Bando. Congenital eye anomalies: More mosaic than thought?. Congenital anomalies. 2019. 59. 3. 56-73
SATO Keita, YAMASHITA Takahiro, OHUCHI Hideyo, SHICHIDA Yoshinori. Diverse Molecular Functions of Photoreceptor Proteins Opn5. Seibutsu Butsuri. 2019. 59. 3. 132-136

Books (1)：

Vertebrate Photoreceptors: Functional Molecular Bases
Springer 2014

Lectures and oral presentations (32)：

網膜色素上皮細胞におけるレーバー先天黒内障16型原因遺伝子KCNJ13のノックアウトは酸化ストレス感受性を高め細胞死を誘導する
(日本酸化ストレス学会学術集会プログラム・抄録集 2023)
カリウムチャネル遺伝子KCNJ13ノックアウト網膜色素上皮では酸化ストレスにより細胞死を生じる
(日本先天異常学会学術集会プログラム・抄録集 2023)
Generation of model medaka for pathology of inherited retinal dystrophy by Crispr/Cas9 mediated genome editing
(2021)
レーバー先天性黒内障16病態モデルiPS-RPEの作製と解析
(日本先天異常学会学術集会プログラム・抄録集 2021)
分子組織化学的解析による真骨魚類が持つ複数のロドプシンの進化過程の解明
(日本解剖学会総会・全国学術集会講演プログラム・抄録集 2020)

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Education (2)：

2007 - 2012 Kyoto University Graduate School of Science
2003 - 2007 Kyoto University Faculty of Science

Professional career (1)：

博士(理学) (京都大学)

Work history (2)：

2016/05 - 現在岡山大学医歯薬学総合研究科細胞組織学分野助教
2012/04 - 2016/04 Kyoto University Graduate School of Science

Committee career (2)：

2023/01 - 2023/12 日本生物物理学会分野別専門委員
2021/01 - 2021/12 日本生物物理学会分野別専門委員

Awards (3)：

2018/09 - Early Career Award in Biophysics Vertebrate photoreceptor, Opn5L1, is the newcomer of opsin acting as a reverse and self-regenerating photoreceptor
2016 - Gordon Research Conference: Photosensory Receptors & Signal Transduction Poster Award Opn5L1 is a reverse and self-regenerating photoreceptor with light-induced covalent chromophore modification
2015 - FASEB Science Research Conference “The Biology and Chemistry of Vision” Best Poster Award Non-mammalian photoreceptor protein Opn5L1 is a photocyclic G protein-coupled receptor

Association Membership(s) (5)：

日本下垂体研究会 , THE JAPANESE ASSOCIATION OF ANATOMISTS , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE ZOOLOGICAL SOCIETY OF JAPAN , THE BIOPHYSICAL SOCIETY OF JAPAN

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