Kondo Natsuko

コンドウナツコ | Kondo Natsuko

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Tumor diagnostics and therapeutics

Research theme for competitive and other funds (7)：

2021 - 2024 悪性グリオーマのBNCT抵抗性の機序解明
2017 - 2020 Clinical trial of boron neutron capture therapy with the combination of successive bevacizumab treatments for recurrent malignant gliomas
2017 - 2019 Bioactive lipids involved in radiation brain necrosis
2016 - 2019 Accuracy improvement for dose and beam-quality estimation of irradiation field for boron neutron capture therapy using dual phantom technique
2014 - 2017 Analysis of pathophysiology of brain radiation necrosis and establishment of novel treatment strategy

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Papers (92)：

Natsuko Kondo, Tadatoshi Kinouchi, Manabu Natsumeda, Juntaro Matsuzaki, Eishu Hirata, Yoshinori Sakurai, Masayasu Okada, Minoru Suzuki. Profile of miRNAs in small extracellular vesicles released from glioblastoma cells treated by boron neutron capture therapy. Journal of neuro-oncology. 2024
Sebastian Flieger, Mao Takagaki, Natsuko Kondo, Marlon R Lutz Jr, Yash Gupta, Hiroki Ueda, Yoshinori Sakurai, Graham Moran, Prakasha Kempaiah, Narayan Hosmane, et al. Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry. International journal of molecular sciences. 2023. 24. 8
Natsuko Kondo, Mitsuko Masutani, Shoji Imamichi, Yoshitaka Matsumoto, Kei Nakai. Strategies for Preclinical Studies Evaluating the Biological Effects of an Accelerator-based BNCT System. Cancer Biotherapy & Radiopharmaceuticals. 2022
Natsuko Kondo, Yoshinori Sakurai, Takushi Takata, Kuniyuki Kano, Kyo Kume, Munetoshi Maeda, Nobuhiko Takai, Shugo Suzuki, Fumihiro Eto, Kenji Kikushima, et al. Persistent elevation of lysophosphatidylcholine promotes radiation brain necrosis with microglial recruitment by P2RX4 activation. Scientific Reports. 2022. 12. 1. 8718-8718
Progress of Boron Neutron Capture Therapy and Biological Problems. Radiation Biology Research Communications. 2022. 57. 1. 63-70

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MISC (142)：

小林奈央, 近藤夏子, 櫻井良憲, 鈴木実, 山口真一, 池川雅哉. 3D Imaging of Metabolic Effects of the Brains from Murine Models of Glioma Treated with Boron Neutron Capture Therapy (BNCT). 質量分析総合討論会講演要旨集. 2023. 71st
近藤夏子, 櫻井良憲, 高田卓志, 前田宗利, 久米恭. Biological Effects on Blood Brain Barrier Induced by Particle Irradiation. 若狭湾エネルギー研究センター研究年報. 2021. 23
古瀬元雅, 川端信司, 鰐渕昌彦, 鰐渕昌彦, 斯波宏行, 竹内孝治, 竹内孝治, 近藤夏子, 田中浩基, 櫻井良憲, et al. Reactor-based boron neutron capture therapy with add-on bevacizumab for recurrent malignant glioma: The final report. 日本脳腫瘍学会プログラム・抄録集. 2021. 39th
近藤夏子, 櫻井良憲, 高田卓志, 久米恭, 前田宗利. Elucidation of iPS-Derived Neuronal Cell Death and Inflammation Induced by Particle Radiation. 若狭湾エネルギー研究センター研究年報. 2020. 22
櫻井良憲, 近藤夏子, 高田卓志, 呼尚徳, 久米恭, 前田宗利. Microdosimetry for Formation of Brain Radiation Necrosis in Particle Irradiation Field using LET Counter. 若狭湾エネルギー研究センター研究年報. 2019. 21

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Lectures and oral presentations (11)：

放射線脳壊死の発症に関連する慢性的なリゾホスファチジルコリンの上昇とミクログリアのP2X4受容体の活性化
(日本放射線腫瘍学会第59回生物部会学術大会 2022)
Radiation Biology on BNCT - what we have known and don't know
(Technical Meeting on Advances in Boron Neutron Capture Therapy, International Atomic Energy Agency (IAEA) 2020)
Boron Neutron Capture Therapy in Kyoto University - from reactor based to accelerator based-
(Kyoto University-UCLA International Symposium 2018)
胸膜播種および胸膜多発腫瘍に対するホウ素中性子捕捉療法
(第72回日本医学放射線学会総会)
局所腫瘍制御と肺転移抑制能から見た低酸素細胞毒連続投与と低温度温熱処置併用放射線照射の意義
(第72回日本医学放射線学会総会)

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Education (2)：

Work history (5)：

2019/04 - 現在 Institute for Integrated Radiation and Nuclear Science, Kyoto university Particle Radiation Oncology Research Center Assistant Professor
2010/04 - 2019/04 Research Reactor Institutes, Kyoto University Particle Radiation Oncology Center Assistant Professor
2014/09 - 2015/08 The Ohio State University James Comprehensive Cancer Center Visiting researcher
2006/04 - 2008/03 奈良県立医科大学脳神経外科
2004/04 - 2006/03 Nara Medical University Nara Medical University Hospital clinical trainee

Committee career (1)：

2018/10 - 現在 International Society for Neutron Capture Therapy Board of Councilor (Biology)

Awards (1)：

Association Membership(s) (7)：

Japan Neurosurgical Society , International Society for Neutron Capture Therapy , 日本中性子捕捉療法学会 , 日本癌学会 , 日本放射線腫瘍学会 , 日本脳腫瘍学会 , 日本放射線影響学会

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