Takata Takumi

タカタタクミ | Takata Takumi

Affiliation and department：
Job title：准教授

Research field (2)： Nutrition and health science , Structural biochemistry

Research keywords (8)：クリスタリン , ヒートショックプロテイン , シャペロン , 電磁波 , 水晶体 , 加齢性疾患 , フォールディング , D-アミノ酸

Research theme for competitive and other funds (5)：

2020 - 2023 蛋白質分子内の老化を可視化する革新的研究
2021 - 蛋白質中D-アミノ酸を基盤とした未知生命科学研究領域の開拓
2017 - 2020 Isomerization of Aspartate residue as a new indicator of aging
2018 - 2018 加齢に応じてタンパク質中に蓄積する異性化アミノ酸残基の生理的意義を解明する研究
2015 - 2017 Age-related Asp Isomerizations in Lens Alpha-crystallin

Papers (43)：

Amber D Rolland, Takumi Takata, Micah T Donor, Kirsten J Lampi, James S Prell. Eye lens β-crystallins are predicted by native ion mobility-mass spectrometry and computations to form compact higher-ordered heterooligomers. Structure (London, England : 1993). 2023
Toshiyuki Chatake, Yasuhide Yanagisawa, Risa Murakami, Tadanori Ohsugi, Hiroyuki Sumi, Takumi Takata, Aya Okuda, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama. Characterization of K-binding factor involved in water-soluble complex of menaquinone-7 produced by Bacillus subtilis natto. Journal of biochemistry. 2023. 174. 4. 383-389
Identification of D-amino acid residues in proteins using mass spectrometry. BUNSEKI KAGAKU. 2022. 71. 6. 319-324
Rintaro Inoue, Yusuke Sakamaki, Takumi Takata, Kathleen Wood, Ken Morishima, Nobuhiro Sato, Aya Okuda, Masahiro Shimizu, Reiko Urade, Noriko Fujii, et al. Elucidation of the mechanism of subunit exchange in αB crystallin oligomers. Scientific reports. 2021. 11. 1. 2555-2555
Kosuke Magami, Naomi Hachiya, Kazuo Morikawa, Noriko Fujii, Takumi Takata. Isomerization of Asp is essential for assembly of amyloid-like fibrils of αA-crystallin-derived peptide. PloS one. 2021. 16. 4. e0250277

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MISC (19)：

Takumi Takat, Noriko Fujii. The spontaneous isomerization of aspartate residues in lens crystallin. 2019. 91. 3. 322-328
Takumi Takata. Heat stability and chaperone like function of aged lens protein mimics. 2019
藤井紀子, 高田匠, 金仁求. 蛋白質中のD-アミノ酸と老化. 臨床免疫・アレルギー科. 2018. 70. 467-474
Takumi Takata. 水晶体構成蛋白質中におけるアミノ酸の自発的化学修飾が引き起こす白内障発症機構に関する研究. 日本白内障学会誌. 2018. 30. 7-12
Noriko Fujii, Takumi Takata. 生命科学におけるパラキラリティーの重要性. 日本眼薬理. 2017. 31. 20-27

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Books (4)：

The Importance of the Idea of“Parachirality” in Life Science.
Elsevier Inc 2017 ISBN:9780128128244
D-Amino acids: Physiology, Metabolism, and Application
Springer 2016 ISBN:9784431560753
皮膚蛋白質中のアスパラギン酸残基異性体と紫外線による皮膚老化の関連性
シーエムシー出版 2015
D-Amino Acids: A New Frontier in Amino Acid and Protein Rsearch-practical Methods and Protocol's
Nova Science Publishers, New York 2007

Lectures and oral presentations (134)：

Analysis of the Susceptible Tryptophan Residues on the Greek Key Motifs of βB2-Crystallin
(9th International Conference on the Lens 2023)
The site-specific impact of modifications of aspartyl residues on lens αB-crystallin
(9th International Conference on the Lens 2023)
加齢性または先天性白内障モデルβB2-クリスタリン変異体Foldingにおける温度依存性
(第62回日本白内障学会総会/第49回水晶体研究会 2023)
βB2-クリスタリン中のGreek key motif内部トリプトファン残基の重要性
(第62回日本白内障学会・第49回水晶体研究会 2023)
Rapid deamidation/isomerization of Asparagine residues and effect of C-terminal adjacent amino acid residues in human lens αA-crystallin
(XXVth biennial meeting of the International Society of Eye Research 2023)

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Education (3)：

2003 - 2006 京都大学理学研究科化学専攻博士後期課程
2001 - 2003 京都大学理学研究科化学専攻博士前期課程
1997 - 2001 Ritsumeikan University College of Science and Engineering Department of Applied Chemistry

Professional career (1)：

理学博士 (京都大学)

Work history (9)：

2021/04 - 現在 JST創発的研究支援事業
2020/04 - 現在 Kyoto University Kyoto University Institute for Integrated Radiation and Nuclear Science
2018/04 - 2020/03 Kyoto University Institute for Integrated Radiation and Nuclear Science
2017/04 - 2018/03 Kyoto University Research Reactor Institute, Division of Radiation Life Science
2016/09 - 2017/03 KYoto University

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Committee career (4)：

2021/12 - 現在 D-アミノ酸学会運営委員
2019/07 - 現在日本白内障学会評議員
2018/08 - 現在日本白内障学会編集委員
2018 - 現在水晶体研究会世話人

Awards (6)：

2017/11 - International Conference of Lens 2017 Travel Award
2017/05 - 日本白内障学会第29回日本白内障学会学術賞
2016/06 - 日本皮膚科学会第115回日本皮膚科学会優秀ポスター賞
2015/12 - International Conference of Lens 2015 Travel Award
2015/08 - D-アミノ酸学会奨励賞

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Association Membership(s) (6)：

水晶体研究会 , International Society of Eye Research , Association for Research in Vision and Ophthalmology , THE JAPANESE SOCIETY FOR CATARACT RESEARCH , THE JAPANESE BIOCHEMICAL SOCIETY , D-AMINO ACID RESEARCH SOCIETY

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