Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma. ソラフェニブは肝細胞癌株において、HGF起因の上皮間葉移行(Epithelial mesenchymal transition)を阻害する.
(第69回日本癌学会学術総会 2010)
Snail and Slug transcription factors induce EMT and down-regulate TP63 mRNA expression in corneal epithelial cells
(2010)
TGF-β induces epithelial mesenchymal transition with SNAI1 and SNAI2 up-regulation in human corneal epithelial cells
(The Association for Research in Vision and Ophthalmology 2010)
Expression levels of EGFR-ligands are up-regulated in EGFR tyrosine kinase inhibitor-resistant cell line.
(AACR 2010)