Yamada Hisatsugu

Affiliation and department：
Research theme for competitive and other funds (11)：

2018 - 2021 光音響イメージングに必須の近赤外蛍光色素複合化ベタイン型ポリマープローブの創製
2017 - 2020 アセチルグルコース修飾ゲフィチニブの放射線増感機序の解明と新規増感剤の創製
2016 - 2019 生体適合性ポリマー”そのもの”を可視化するDDSイメージングの新手法開発
2015 - 2018 光超音波-磁気共鳴デュアルイメージングプローブの創製
2015 - 2016 多重共鳴NMR技術を機軸とする脳内モノアミン代謝の直接解析ツールの開発

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Papers (35)：

Toru Tasaka, Emi Kuwada, Yuka Izuchi, Ryohei Nishigawa, Hisatsugu Yamada, Hideki Unuma, Ken Tokunaga, Akio Hayakawa, Akiteru Go, Kikyo Go, et al. Concentration-dependent, Activation of Inflammatory/Anti-inflammatory Functions of Macrophages by Hydrolyzed Whey Protein. Anticancer Research. 2018. 38. 7. 4299-4304
Tomoko Kaneko, Masahide Tominaga, Risa Kouzaki, Ayaka Hanyu, Kazuki Ueshima, Hisatsugu Yamada, Masaki Suga, Tomohiro Yamashita, Tomoaki Okimoto, Yoshihiro Uto. Radiosensitizing Effect of 5-Aminolevlinic Acid and Protoporphyrin IX on Carbon-ion Beam Irradiation. Anticancer Research. 2018. 38. 7. 4313-4317
Takahiro Hara, Masahide Tominaga, Kazunori Yajyu, Risa Kouzaki, Hisatsugu Yamada, Mikiharu Sasaki, Shota Azane, Yoshihiro Uto. Effect of Dose Rate on Antitumor Activity in Hypoxic Cells by Using Flattening Filter Free Beams. International Journal of Radiation Research. 2018. 16. 2. 197-205
Yusei Shinohara, Yoshio Endo, Chiaki Abe, Ikkyu Shiba, Masahiro Ishizuka, Tohru Tanaka, Yutaka Yonemura, Shun-Ichiro Ogura, Masahide Tominaga, Hisatsugu Yamada, et al. Development of a novel Schiff base derivative for enhancing the anticancer potential of 5-aminolevulinic acid-based photodynamic therapy. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY. 2017. 20. 182-188
Ikkyu Shiba, Risa Kouzaki, Hisatsugu Yamada, Yoshio Endo, Takahisa Takin, Hiroshi Sato, Keiko Kitazato, Teruyoshi Kageji, Shinji Nagahiro, Yoshihiro Uto. Design and Synthesis of Novel Anti-metastatic Hypoxic Cytotoxin TX-2137 Targeting AKT Kinase. ANTICANCER RESEARCH. 2017. 37. 7. 3877-3883

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MISC (10)：

山田久嗣. 生体内代謝プロセスの多重共鳴 NMR モニタリングと多重共鳴 MRI に展開可能な高感度化分子プローブの開発. 日本化学会生体機能関連化学部会ニュースレター. 2012. 27. 3. 17-20
Kazuhito Tanabe, Hisatsugu Yamada, Sei-ichi Nishimoto. Photoelectrochemical Approach to Detection of Methylation Status of Cytosine Base in DNA. Nucleic Acids Symposium Series. 2009. 53. 1. 205-206
Takeo Ito, Aiko Hayashi, Tsukasa Uchida, Kazuhito Tanabe, Hisatsugu Yamada, Sei-ichi Nishimoto. Photo-Induced Electron Transfer Reaction in Diaminostilbene-Tethered DNA Duplexes. Nucleic Acids Symposium Series. 2009. 53. 1. 201-202
Hisatsugu Yamada, Yuya Kitauchi, Kazuhito Tanabe, Takeo Ito, Sei-ichi Nishimoto. Efficient Photooxidative Strand Cleavage at 5-Methylcytosine in DNA by Sensitization with 9,10-Anthraquinone-Tethered Oligonucleotides. Nucleic Acids Symposium Series. 2009. 53. 1. 209-210
Kazuhito Tanabe, Emi Kuraseko, Eiji Matsumoto, Hisatsugu Yamada, Takeo Ito, Sei-ichi Nishimoto. Radiolytic Ligation of Oligodeoxynucleotides Possessing Disulfide Bond. Nucleic Acids Symposium Series. 2008. 52. 1. 459-460

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Patents (7)：

POLYMER AND CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING INCLUDING THE POLYMER
重合体,前記重合体を有する光音響イメージング用造影剤
Polynuclear and Multiple Magnetic Resonance Imaging Method and Imaged Device
多核多重核磁気共鳴画像化方法
POLYMER, CONTRAST AGENT FOR NUCLEAR MAGNETIC RESONANCE ANALYSIS OR MAGNETIC RESONANCE IMAGING USING THE POLYMER, COMPOUND, AND METHOD OF NUCLEAR MAGNETIC RESONANCE ANALYSIS AND METHOD OF MAGNETIC RESONANCE IMAGING USING THE POLYMER

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Books (2)：

Ruthenium-based catalysts for aerobic oxidation of alcohols
RSC Publishing 2014
Magnetic Nanoparticles for Multimodal Bio-imaging
Nova Science Publishers 2014

Education (3)：

2005 - 2008 Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University
2003 - 2005 Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University
2003 - Faculty of Engineering, Kyoto University

Professional career (1)：

博士(工学) (京都大学)

Work history (6)：

2017/04 - 現在徳島大学大学院社会産業理工学研究部講師
2016/04 - 2017/03 徳島大学大学院生物資源産業学研究部講師
2015/01 - 2016/03 The University of Tokushima Institute of Technology and Science
2010/04 - 2014/12 Advanced Biomedical Engineering Research Unit, Center for the Promotion of Interdisciplinary Education and Research, Kyoto Uni-versity
2008/04 - 2010/03 Nanomedicine Merger Education Unit, Kyoto University

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Committee career (1)：

2015/04 - 2017/03 社団法人有機合成化学協会編集協力委員

Awards (5)：

2014/05 - (公社) 新化学技術推進協会第3回新化学技術研究奨励賞
2012/09 - (公社)日本化学会生体機能関連化学部会第13回バイオ関連化学シンポジウム講演賞(生体機能関連化学部会講演賞)
2012/03 - The Chemical Society of Japan 日本化学会第92春季年会優秀講演賞(学術)
2010/03 - (財) 京都高度技術研究所バイオ計測・試薬研究会奨励講演賞
2006/03 - The Chemical Society of Japan 日本化学会第86春季年会学生講演賞

Association Membership(s) (7)：

American Chemical Society , 日本ケミカルバイオロジー学会 , 日本分子イメージング学会 , The Japanese Photochemistry Association , 近畿化学協会 , THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN , The Chemical Society of Japan

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