Hiromi Uramoto | Researcher Information

2019 - 2022 腸管膜腸液・粘液分泌が関わる排便機構の解明:遺伝要因を考慮した便秘の分類と改善
2015 - 2018 腸管膜粘液分泌が関わる排便機構の解明:CFTR遺伝子多型と慢性機能性便秘との連関
2006 - 2009 心筋虚血・再灌流障害に対するCFTRの保護機能のメカニズム

Ravshan Z. Sabirov, Petr G. Merzlyak, Toshiaki Okada, Md Rafiqul Islam, Hiromi Uramoto, Tomoko Mori, Yumiko Makino, Hiroshi Matsuura, Yu Xie, Yasunobu Okada. The organic anion transporter SLCO2A1 constitutes the core component of the Maxi-Cl channel. EMBO JOURNAL. 2017. 36. 22. 3309-3324
Md. Rafiqul Islam, Hiromi Uramoto, Toshiaki Okada, Ravshan Z. Sabirov, Yasunobu Okada. Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2012. 303. 9. C924-C935
Hiromi Uramoto, Toshiaki Okada, Yasunobu Okada. Protective Role of Cardiac CFTR Activation Upon Early Reperfusion Against Myocardial Infarction. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. 2012. 30. 4. 1023-1038
S Tanabe, XM Wang, N Takahashi, H Uramoto, Y Okada. HCO3- independent rescue from apoptosis by stilbene derivatives in rat cardiomyocytes. FEBS LETTERS. 2005. 579. 2. 517-522
N Takahashi, XM Wang, S Tanabe, H Uramoto, K Jishage, S Uchida, S Sasaki, Y Okada. CIC-3-independent sensitivity of apoptosis to Cl- channel blockers in mouse cardiomyocytes. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. 2005. 15. 6. 263-270

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Md Rafiqul Islam, Ravshan Z. Sabirov, Hiromi Uramoto, Yasunobu Okada. Electrophysiological and pharmacological study of the maxi-anion channel in L929 murine fibrosarcoma cells. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2010. 60. S122-S122
Hiromi Uramoto, Yasunobu Okada. PROTECTION OF CARDIOMYOCYTES FROM ISCHEMIC/REPERFUSION INJURY BY CFTR ACTIVATORS ADMINISTRATED UPON REPERFUSION IN VIVO. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2009. 59. 318-318
AK Dutta, RZ Sabirov, H Uramoto. Activation of ATP-releasing maxi-anion channel in hypotonic, ischemic or hypoxic conditions in rat cardiomyocytes. FASEB JOURNAL. 2005. 19. 5. A1165-A1166
K. Umegaki, M. Aoshima, S. Hirota, H. Uramoto, T. Esashi. Simultaneous dietary supplementation of sodium cholate and beta-carotene markedly enhances accumulation of beta-carotene in mice. Journal of Nutrition. 1995. 125. 12. 3081-3086

虚血性心臓傷害の新保護法

基礎から学ぶ食品化学実験テキスト
建帛社 2017
新版マスター食品学I
建帛社 2016
食品加工学と実習・実験
光生館 2016
チャネルレギュレーターとしてのABCタンパク質
学会出版センター 2004
健康・栄養知っておきたい基礎知識(国立健康・栄養研究所国民栄養振興会編)
第一出版 1999

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便秘症状と汗中塩分濃度からみたCFTRクロライドイオンチャネル機能との関係
(第72回日本栄養・食糧学会大会(岡山) 2018)
CFTRチャネル活性化成分摂取の便秘改善効果におよぼす食物繊維及び水分摂取量の影響
(第64回日本栄養改善学会学術総会(徳島) 2017)
Molecular identification of two types of volume-activated anion channels involved in multiple functions controlling cell life.
(2017)
Identification of the key molecule of Maci-Cl channel by proteomics and genome-wide approaches.
(2017)
Molecular verification for the Maxi-Cl channel molecule as a cellular ATP release pathway.
(2017)

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理学 (総合研究大学院大学)

2018/04 - 現在 Jin-Ai University Department of Faculty of Human Life professor
2013/04 - 2018/03 Jin-Ai University Department of Faculty of Human Life associate professor
2011/04 - 2013/03 Jin-Ai University Department of Faculty of Human Life university lecturer
2005 - 2011 National Institute for Physiological Sciences Department of Cell Physiology

PHYSIOLOGICAL SOCIETY OF JAPAN , JAPANESE ASSOCIATION FOR DIETARY FIBER RESEARCH , THE JAPANESE SOCIETY OF NUTRITION AND DIETETICS , JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE