Sanada Masashi

Affiliation and department：

Research field (1)： Hematology and oncology

Research theme for competitive and other funds (13)：

2021 - 2025 悪性リンパ腫疑い不明熱患者に対するリキッドバイオプシーによる診断法の確立
2020 - 2023 Understanding of the onset and recurrence pattern of intractable acute lymphocytic leukemia based on clone analysis
2020 - 2023 Integrated analysis of mechanisms of genetic susceptibility to cancer and clonal evolution in pediatric cancer
2017 - 2020 The molecular pathogenenesis of pediatric acute lymphoblastic leukemia through the understanding of clonal artitectures
2014 - 2019 Understanding of stem cell aging as the onset basis of hematopoietic tumors in elderly patients

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Papers (258)：

Thao Nguyen, Tomomi Aida, Yuka Iijima-Yamashita, Minori Tamai, Akiko Nagamachi, Keiko Kagami, Chiaki Komatsu, Shin Kasai, Koshi Akahane, Kumiko Goi, et al. Application of prime editing system to introduce TP53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line. Cancer science. 2024
伊藤勇太, 木暮泰寛, 古屋淳史, 千葉健一, 岡田愛, 白石友一, 月田早智子, 伊豆津宏二, 坂田征士, 土橋映仁, et al. 節外性NK/T細胞リンパ腫における宿主およびウイルスゲノムにおける体細胞異常の全体像(Landscape of somatic alterations in host and viral genomes in extranodal NK/T-cell lymphoma). 日本癌学会総会記事. 2023. 82回. 388-388
Yukino Kojima, Fumika Kawashima, Takahiko Yasuda, Koya Odaira, Yuichiro Inagaki, Chiharu Yamada, Ami Muraki, Mina Noura, Shuichi Okamoto, Shogo Tamura, et al. EBF1-JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity. International journal of hematology. 2023. 118. 1. 65-74
Hirotoshi Sakaguchi, Katsustugu Umeda, Itaru Kato, Kimiyoshi Sakaguchi, Hidefumi Hiramatsu, Hiroyuki Ishida, Hiromasa Yabe, Hiroaki Goto, Yuta Kawahara, Yuka Iijima Yamashita, et al. Safety and efficacy of post-haematopoietic cell transplantation maintenance therapy with blinatumomab for relapsed/refractory CD19-positive B-cell acute lymphoblastic leukaemia: protocol for a phase I-II, multicentre, non-blinded, non-controlled trial (JPLSG SCT-ALL-BLIN21). BMJ open. 2023. 13. 4. e070051
Thao Thu Thi Nguyen, Yoichi Tanaka, Masashi Sanada, Masumi Hosaka, Minori Tamai, Keiko Kagami, Chiaki Komatsu, Shinpei Somazu, Daisuke Harama, Shin Kasai, et al. CRISPR/Cas9-mediated induction of relapse-specific NT5C2 and PRPS1 mutations confers thiopurine resistance as a relapsed lymphoid leukemia model. Molecular pharmacology. 2023

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MISC (227)：

Shinobu Tsuzuki, Takahiko Yasuda, Masahito Kawazu, Toshihide Ueno, Sivasundaram Karnan, Akinobu Ota, Masashi Sanada, Hirokazu Nagai, Akihiro Tomita, Yoshiyuki Takahashi, et al. Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia. CANCER SCIENCE. 2022. 113. 1236-1236
Yotaro Ochi, Kenichi Yoshida, Ko Sasaki, Noriko Hosoya, Yusuke Shiozawa, Yasuhito Nannya, Takayuki Ishikawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, et al. Genetic profiling and prognosis of blast crisis in chronic myeloid leukemia. CANCER SCIENCE. 2021. 112. 454-454
June Takeda, Kenichi Yoshida, Akinori Yoda, Yasuhito Nannya, Masahiro Nakagawa, Yotaro Ochi, Ayana Kon, Tetsuichi Yoshizato, Yusuke Shiozawa, Yuichi Shiraishi, et al. JAK STAT Pathway is a Promising Therapeutic target in Acute Erythroid Leukemia. CANCER SCIENCE. 2021. 112. 453-453
高折晃史, 遠西大輔, 村松秀城, 伊豆津宏二, 真田昌, 鈴木達也, 南谷泰仁, 片岡圭亮, 前田高宏. 造血器腫瘍における遺伝子パネル検査の提供体制構築およびガイドライン作成に関する研究ゲノム医療教育に関する研究. 造血器腫瘍における遺伝子パネル検査の提供体制構築およびガイドライン作成に関する研究令和2年度総括・分担研究報告書(Web). 2021
奥田瑠璃花, 南谷泰人, 越智陽太郎, 蝶名林和久, 蝶名林和久, 牧島秀樹, 吉里哲一, 永田安伸, 竹田淳恵, 吉田健一, et al. ETNK1 mutations defines a subclass of der(1;7)(q10;p10) in myelodysplastic syndromes. 日本血液学会学術集会抄録(Web). 2021. 83rd

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