Research theme for competitive and other funds (4)：
2018 - 2023 Analysis of immune regulatory mechanisms mediated by mRNA metabolism
2019 - 2022 Study of mRNA translation in immune system
2016 - 2019 Study of UPF1-mediated mRNA regulation in immune system
2013 - 2015 Analysis of posttranscriptional mechanisms of Regnase-1-mediated mRNA decay in innate immune system
Papers (36)：
Takuya Uehata, Shinnosuke Yamada, Daisuke Ori, Alexis Vandenbon, Amir Giladi, Adam Jelinski, Yasuhiro Murakawa, Hitomi Watanabe, Kazuhiro Takeuchi, Kazunori Toratani, et al. Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz. Blood. 2023
Ai Yaku, Tadakatsu Inagaki, Ryotaro Asano, Makoto Okazawa, Hiroyoshi Mori, Ayuko Sato, Fabian Hia, Takeshi Masaki, Yusuke Manabe, Tomohiko Ishibashi, et al. Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages. Circulation. 2022. 101161CIRCULATIONAHA122059435
Kotaro Akaki, Takashi Mino, Osamu Takeuchi. DSP-crosslinking and Immunoprecipitation to Isolate Weak Protein Complex. BIO-PROTOCOL. 2022. 12. 15
Ka Man Tse, Alexis Vandenbon, Xiaotong Cui, Takashi Mino, Takuya Uehata, Keiko Yasuda, Ayuko Sato, Tohru Tsujimura, Fabian Hia, Masanori Yoshinaga, et al. Enhancement of Regnase-1 expression with stem loop-targeting antisense oligonucleotides alleviates inflammatory diseases. Science translational medicine. 2022. 14. 644. eabo2137
Yee Kien Chong, Sarang Tartey, Yuki Yoshikawa, Koshi Imami, Songling Li, Masanori Yoshinaga, Ai Hirabayashi, Guohao Liu, Alexis Vandenbon, Fabian Hia, et al. Cyclin J-CDK complexes limit innate immune responses by reducing proinflammatory changes in macrophage metabolism. Science signaling. 2022. 15. 729. eabm5011
