Rchr
J-GLOBAL ID：201401069909640685
Update date: Mar. 11, 2024
Fujiwara Takahiro
フジワラ タカヒロ | Fujiwara Takahiro
Affiliation and department：
Job title：
Program-Specific Associate Professor
Homepage URL (1)：
https://kyouindb.iimc.kyoto-u.ac.jp/j/dP8hT
Research field (3)：
Nanobioscience
, Cell biology
, Biophysics
Research keywords (2)：
Function of the clellular plasma membrane
, Single-molecule nanobiology
Research theme for competitive and other funds (15)：
- 2021 - 2026 細胞内分子の構造・動態・機能相関を調べるためのクロススケール可視化制御技術の開発
- 2021 - 2025 超速1分子超解像法による、シグナル経路統合を担う液状ナノ共通シグナル基盤の解明
- 2020 - 2023 Direct single-molecule observation of elementary molecular complex formation processes induced by the compartmentalized plasma membrane
- 2018 - 2021 Development of high-speed super-resolution membrane skeleton elasticity mapping and its application to cell motility analysis
- 2016 - 2021 Signal transduction induced by ultra-transient receptor complexes and its regulation by actin skeleton: a single-molecule study
- 2016 - 2019 Dynamic focal adhesion molecular islands as revealed by super-spatiotemporal-resolution single fluorescent-molecule localization microscopy
- 2013 - 2018 Analysis of moisturization mechanism of stratum corneusm
- 2016 - 2017 Diamond NVC for protein analysis
- 2014 - 2017 Site-specific modification of respiratory complex I for single molecule analysis
- 2014 - 2017 Spatio-temporal analysis of extracellular ATP signaling of pancreatic islets
- 2015 - 2017 Unraveling molecular-selective diffusion barrier at the base of primary cilium by developing single-molecule super-resolution microscopy
- 2014 - 2016 Revealing functional integration of small and short-lived molecular complexes by 3-dimensional super-resolved localization microscopy
- 2013 - 2015 Revealing molecular-selective filter mechanism based on diffusion barrier at the base of primary cilium
- 2012 - 2014 Development of high-speed 3-dimensional single-molecule tracking and its application to studies of small and short-lived cell adhesion molecule complexes
- 2009 - 2011 Development of single-molecule tracking using fluorescent silicon nanoparticles and its application to signaling mechanisms in clathrin-coated pits
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Papers (105)：
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Masahiko Hirano, Yasuo Yonemaru, Satoshi Shimozono, Mayu Sugiyama, Ryoko Ando, Yasushi Okada, Takahiro Fujiwara, Atsushi Miyawaki. StayGold photostability under different illumination modes. Scientific reports. 2024. 14. 1. 5541-5541
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Kenichi Kawano, Yuki Kuzuma, Koichi Yoshio, Kenta Hosokawa, Yuuto Oosugi, Takahiro Fujiwara, Fumiaki Yokoyama, Katsumi Matsuzaki. Extracellular-Vesicle Catch-and-Release Isolation System Using a Net-Charge Invertible Curvature-Sensing Peptide. Analytical chemistry. 2024. 96. 9. 3754-3762
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Ryoko Ando, Satoshi Shimozono, Hideo Ago, Masatoshi Takagi, Mayu Sugiyama, Hiroshi Kurokawa, Masahiko Hirano, Yusuke Niino, Go Ueno, Fumiyoshi Ishidate, et al. StayGold variants for molecular fusion and membrane-targeting applications. Nature Methods. 2023
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Takahiro K Fujiwara, Shinji Takeuchi, Ziya Kalay, Yosuke Nagai, Taka A Tsunoyama, Thomas Kalkbrenner, Kokoro Iwasawa, Ken P Ritchie, Kenichi G N Suzuki, Akihiro Kusumi. Development of ultrafast camera-based single fluorescent-molecule imaging for cell biology. The Journal of cell biology. 2023. 222. 8
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Takahiro K Fujiwara, Taka A Tsunoyama, Shinji Takeuchi, Ziya Kalay, Yosuke Nagai, Thomas Kalkbrenner, Yuri L Nemoto, Limin H Chen, Akihiro C E Shibata, Kokoro Iwasawa, et al. Ultrafast single-molecule imaging reveals focal adhesion nano-architecture and molecular dynamics. The Journal of cell biology. 2023. 222. 8
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MISC (28)：
Lectures and oral presentations (69)：
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超高速1蛍光分子観察による接着斑メゾ構造分子動態の解明
(定量生物学の会 第11回年会 セッション1 「時間と空間の限界を突破する」 2024)
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Mesoscopic architecture and molecular dynamics in focal adhesions as revealed by ultrafast single-molecule imaging
(第61回日本生物物理学会年会 シンポジウム3SEA「細胞のメゾ構造体の形成と機能の機構:先端イメジング法による解明」 2023)
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Mesoscopic architecture and molecular dynamics in focal adhesions as revealed by ultrafast single-molecule imaging
(The East Asia Single Molecule Biology Symposium 2023 (EASMB 2023) 2023)
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Unraveling mesoscopic organization of the plasma membrane by ultrafast single fluorescent-molecule tracking and localization microscopy
(NanoLSI Open Seminar at NanoLSI, Kanazawa University 2021)
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Organization of focal adhesion based on actin-induced compartments and dynamic protein islands as revealed by ultrafast single-molecule imaging
(1st WPI NanoLSI-iCeMS Joint Symposium on Nanoimaging and Advanced Materials for Life Science 2020)
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Education (4)：
- 1997 - 1998 Nagoya University Graduate School of Science
- 1995 - 1998 The University of Tokyo Graduate School of Arts and Sciences Department of Life Sciences
- 1993 - 1995 The University of Tokyo Graduate School of Arts and Sciences Department of Life Sciences
- 1988 - 1993 Kyoto University Faculty of Science
Professional career (1)：
- D.Sc. (Nagoya University)
Work history (10)：
- 2017/04 - 現在 Kyoto University Bioanalysis Unit, Analysis Center, Institute for Integrated Cell-Material Sciences, KUIAS Unit Leader
- 2017/04 - 現在 Kyoto University KUIAS, Institute for Integrated Cell-Material Sciences Program-Specific Associate Professor
- 2015/05 - 2017/03 Kyoto University Institute for Integrated Cell-Material Sciences Program-Specific Research Center Associate Professor
- 2013/04 - 2017/03 Kyoto University Center for Meso-Bio Single Molecule Imaging, Institute for Integrated Cell-Material Sciences Deputy Director
- 2010/12 - 2015/04 Kyoto University Institute for Integrated Cell-Material Sciences Program-Specific Research Center Senior Lecturer
- 2008/04 - 2010/11 Kyoto University Institute for Integrated Cell-Material Sciences Research Assistant Professor
- 2005/04 - 2010/03 Kyoto University Institute for Frontier Medical Sciences Research Assistant Professor
- 2005/04 - 2010/03 ICORP, JST Research Fellow
- 2003/10 - 2005/03 SORST, JST Research Fellow
- 1998/10 - 2003/09 ERATO, JST Research Fellow
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Association Membership(s) (2)：
Biophysical Society
, The Biophysical Society of Japan
