Hattori Akira

2017 - 2020 Promoting mechnisms of embryonic signals in embryo implantation induced by the immune system

2017 - 2019 Identification and analysis of circulating embryonic stem cells derived from human chorionic stroma at early stage

2016 - 2019 Identification of non-canonical degradation pathway of HIF-1 alpha promoted by de-ubiqutinating enzyme inhibitor.

2016 - 2019 Stereocontrolled synthesis of poly-substituted medium-sized cyclic compounds by electrocyclic ring opening reaction and the synthesis of biologically active molecules

2016 - 2017 Analysis of chorionic villi-derived embryo stem cells by novel sten cell markers, laeberin and hTERT

2015 - 2017 Role of ERAP1 in the pathogenesis of mental disorders

2014 - 2017 Identification of embryo-derived implantation-inducing factors (embryonic signals) and their clinical application

2013 - 2016 Pathophysiological roles of M1 aminopeptidases

2013 - 2016 Discovery of new reactions and utilities of 4-membered carbocyles based on their unique ring strains.

2012 - 2015 Role of aminopeptidases in atherosclerosis

2012 - 2014 Mechanism of unanchored polyubiquitin chain production

2011 - 2014 Analysis of maternal recognition through embryo-specific sugar antigen and its inducing mechanisms for embryo implantation and placentation

2011 - 2014 Biochemical and physiological studies on deubiquitinating enzymes based on an analysis of the enzymatic activity dynamics

2011 - 2013 抗原トリミングアミノペプチダーゼの作用発現メカニズムと制御

2012 - 2012 Induction of immune-tolerance by a novel human trophoblast-specific soluble factor, laeverin

2010 - 2010 免疫系による発生初期胚の認識機構-透明帯を利用した哺乳類の着床誘導戦略の証明-

2008 - 2010 Biological Function of the M1 Family of Human Aminopeptidases

2008 - 2010 Analysis of tissue remodeling mechanisms by circulating blood cells during human reproduction

2006 - 2008 Mechanisms of Enzymatic Action of the Oxytocinase Subfamily of Aminopeptidases

2006 - 2007 小胞体におけるMHCクラスI提示抗原のN末端トリミング過程の分子メカニズム解析

2004 - 2005 抗原ペプチドプロセシングにおける小胞体アミノペプチダーゼの作用メカニズムの解明

2004 - 2005 血管新生の制御を目指した新たな標的分子の探索

2003 - 2005 The oxytocinase subfamily of M1 aminopeptidases

2002 - 2003 オキシトシナーゼサブファミリーの細胞内膜系局在の意義およびそのメカニズムの解明

2000 - 2001 オキシトシナーゼサブファミリーに属する新規酵素の生理機能の解明

1999 - 2001 STRUCTURE AND FUNCTION OF NOVEL AMINOPEPTIDASES BELONGING TO OXYTOCINASE SUB-FAMILY

1998 - 1999 腫瘍壊死因子によるアポトーシス誘導のシグナル系におけるcPLA_2の役割の解明