Rchr
J-GLOBAL ID：201401073421632966   Update date: Feb. 29, 2024

Ryosuke Satoh

サトウ リヨウスケ | Ryosuke Satoh
Affiliation and department：
Kindai University Faculty of Pharmacy Department of Pharmaceutical Sciences

About Kindai University Faculty of Pharmacy Department of Pharmaceutical Sciences


Job title： Lecturer
Research field  (5)： Genetics ,  Chemical biology ,  Pharmaceuticals - health and biochemistry ,  Cell biology ,  Molecular biology
Research keywords  (11)： Liquid-liquid phase separation ,  Phase separation ,  Phosphorylation ,  Stress granule ,  Stress response ,  Cancer ,  Fission yeast ,  Chemical biology ,  RNA-binding protein ,  RNA ,  Signal transduction
Research theme for competitive and other funds  (6)：
  • 2023 - 2026 RNA相分離によるシグナル伝達スイッチを介した細胞運命制御機構
  • 2020 - 2023 RNA顆粒ダイナミクスの制御機構解明と難治性疾患治療への応用
  • 2021 - 2022 RNA相分離によって制御されるシグナル伝達スイッチ機構の解明
  • 2017 - 2018 RNA結合タンパク質を標的としたRNA顆粒形成調節薬スクリーニング法の確立と難治性疾患治療への応用
  • 2012 - 2014 IRES-dependent translational mechanism regulating tissue-specific replication of poliovirus
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Papers (43)：
  • Reiko Sugiura, Ryosuke Satoh, Naofumi Tomimoto, Teruaki Takasaki. Phase Separation Orchestrates Cancer Signaling: Stress Granules as a Promising Target for Cancer Therapy. Phase Separation in Living Cells. 2023. 209-252
  • Teruaki Takasaki, Ryosuke Utsumi, Erika Shimada, Asuka Bamba, Kanako Hagihara, Ryosuke Satoh, Reiko Sugiura. Atg1, a key regulator of autophagy, functions to promote MAPK activation and cell death upon calcium overload in fission yeast. Microbial cell (Graz, Austria). 2023. 10. 6. 133-140
  • Golam Iftakhar Khandakar, Yoichi Miyamoto, Ryosuke Satoh, Kenta Kishimoto, Mingzuo Xie, Mengyu Shih, Teruaki Takasaki, Genzoh Tanabe, Masahiro Oka, Reiko Sugiura. ACAGT-007a, an anti-cancer compound that modulates ERK MAPK signaling, induces nuclear enrichment of phosphorylated ERK in T3M4 pancreatic cancer cells. Genes to cells : devoted to molecular & cellular mechanisms. 2023
  • Ryosuke Satoh, Taemi Tanaka, Nobuyasu Yoshida, Chiaki Tanaka, Teruaki Takasaki, Reiko Sugiura. Fission Yeast PUF Proteins Puf3 and Puf4 Are Novel Regulators of PI4P5K Signaling. Biological and Pharmaceutical Bulletin. 2023. 46. 2. 163-169
  • Teruaki Takasaki, Reo Obana, Daiki Fujiwara, Naofumi Tomimoto, Golam Iftakhar Khandakar, Ryosuke Satoh, Reiko Sugiura. ACA-28, an anticancer compound, induces Pap1 nuclear accumulation via ROS-dependent and -independent mechanisms in fission yeast. microPublication biology. 2023. 2023
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MISC (75)：
  • 萩原加奈子, 萩原加奈子, 佐藤亮介, 前田拓也, 杉浦麗子. Effects of an immune modulator FTY720 (fingolimod) on signaling pathways that control cell proliferation in fission yeast. 衛生薬学・環境トキシコロジー講演要旨集. 2023. 2023
  • 山田南, 杉本恵崇, 黒崎亮, 高崎輝恒, 佐藤亮介, 杉浦麗子. Valproic acid impacts aggregation and toxicity associated with α-Synuclein overproduction~Crosstalk between α-synuclein and membrane traffic and glycosylation~. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 吉田展康, 川崎有紀, 原信樹, 佐藤亮介, 高崎輝恒, 杉浦麗子. Relationship between phosphorylation of a KH-type RNA-binding protein Rnc1 and its translocation to stress granules. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 田中達也, 佐藤亮介, 高崎輝恒, 杉浦麗子, 杉浦麗子. Role of the DNA damage response protein BRAT1 in the ROS mediated induction of cell death induced by a novel anticancer compound ACAGT-007a. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 巽祐司, 高崎輝恒, 杉本恵崇, 黒崎亮, 山田南, 壽美月, 佐藤亮介, 杉浦麗子. α-synが引き起こす細胞死を増強する細胞内輸送経路のステップの特定. 日本薬理学雑誌. 2023. 158. Supplement
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Patents (2)：
Lectures and oral presentations  (261)：
  • ERK: A DOUBLE-EDGED SWORD IN CANCER. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer
    (The Protein Phosphatases Conference Jointly hosted by FASEB and the Japanese Association for Protein Phosphatase Research (JAPPR) 2022)
  • FISSION YEAST PUF PROTEINS PUF3 AND PUF4 ARE NOVEL REGULATORS OF PI4P5K SIGNALING
    (The Protein Phosphatases Conference Jointly hosted by FASEB and the Japanese Association for Protein Phosphatase Research (JAPPR) 2022)
  • ACAGT-007a, A NEW ERK MAPK SIGNALING MODULATOR, WHEN COMBINED WITH AKT SIGNALING INHIBITOR, INHIBITS CELL GROWTH AND TRIGGERS APOPTOSIS IN PANCREATIC CANCER CELLS
    (The Protein Phosphatases Conference Jointly hosted by FASEB and the Japanese Association for Protein Phosphatase Research (JAPPR) 2022)
  • ACA-28, A NOVEL ANTI-CANCER COMPOUND, INDUCES ERK- OR AUTOPHAGY-DEPENDENT APOPTOSIS DEPENDING ON THE CELL TYPES ON OSTEOSARCOMA
    (The Protein Phosphatases Conference Jointly hosted by FASEB and the Japanese Association for Protein Phosphatase Research (JAPPR) 2022)
  • REGULATION OF PKC/MAPK SIGNALING BY PHASE SEPARATION MEDIATED BY AN RNA HELICASE Ded1
    (The Protein Phosphatases Conference Jointly hosted by FASEB and the Japanese Association for Protein Phosphatase Research (JAPPR) 2022)
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Professional career (1)：
  • 博士(薬学)
Work history (5)：
  • 2023/09 - 現在 McGill University Rosalind and Morris Goodman Cancer Institute, Faculty of Medicine and Health Sciences Visiting Professor
  • 2019/04 - 現在 Kindai University Department of Pharmaceutical Sciences, Faculty of Pharmacy Lecuturer
  • 2014/04 - 2019/03 Kindai University Department of Pharmaceutical Sciences, Faculty of Pharmacy Assistant Professor
  • 2012/04 - 2014/03 Microbial Chemistry Research Foundation Postdoctoral fellow
  • 2010/04 - 2012/03 Japan Society for the Promotion of Science(JSPS) Research Fellowship for Young Scientists(DC2)
Committee career (6)：
  • 2019/09 - 現在 近畿大学薬学部 留学生支援部会
  • 2014/04 - 現在 近畿大学薬学部 予算委員会 機器備品設備部会 ワーキンググループ
  • 2014/04 - 現在 近畿大学薬学部 実務実習実施委員会 OSCE実施部会 ワーキンググループ
  • 2014/04 - 現在 近畿大学薬学部 卒業研究実施検討委員会 創薬科学科卒業研究発表実施部会 ワーキンググループ
  • 2020/10 - 2022/03 近畿大学 カリキュラム検討委員会 創薬科学科部会
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Awards (2)：
  • 2019/09 - 酵母遺伝学フォーラム 会長賞 RNA結合タンパク質Pumilioによるイノシトールリン脂質代謝経路の制御
  • 2018/01 - 日本薬学会近畿支部 平成29年度 日本薬学会近畿支部奨励賞 RNA結合タンパク質の時間・空間的制御を介したMAPKシグナル調節機構 -RNA結合タンパク質の局在制御機構と創薬への応用-
Association Membership(s) (7)：
Japanese Association for Protein Phosphatase Research ,  YEAST GENETICS SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE RNA SOCIETY OF JAPAN
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