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J-GLOBAL ID：201401076516935361   Update date: Mar. 26, 2024

Hirashima Tsuyoshi

ヒラシマ ツヨシ | Hirashima Tsuyoshi
Affiliation and department：
National University of Singapore Mechanobiology Institute

About National University of Singapore Mechanobiology Institute


Job title： Principal Investigator
Other affiliations (1)：
  • National University of Singapore  Department of Physiology   Research Assistant Professor
Homepage URL  (1)： https://sites.google.com/view/hirashima-group/home
Research field  (4)： Cell biology ,  Biophysics ,  Morphology, anatomy ,  Developmental biology
Research keywords  (7)： Reproduction ,  Imaging ,  Systems Biology ,  Mechanobiology ,  Mathematical Modeling ,  Development ,  Tissue morphogenesis
Research theme for competitive and other funds  (12)：
  • 2019 - 2023 曲率に対する力学応答システムによる分岐形態形成
  • 2021 - 2022 Biophysical understanding of cell competition mechanisms for multicellular autonomy
  • 2021 - 2022 精子アクティブマターによる生体内集団動態の物理機構
  • 2019 - 2022 Collective cell migration by activation wave of growth factor signal transduction cascade
  • 2021 - 2022 Understanding multicellular autonomy by competitive cell-cell communications
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Papers (41)：
  • Tsuyoshi Hirashima, Michiyuki Matsuda. ERK-mediated curvature feedback regulates branching morphogenesis in lung epithelial tissue. Current Biology. 2024
  • Ankita Nitin Nayak, Tsuyoshi Hirashima. Tug-of-war via ERK signaling pathway for tissue organization - ERK activation to force generation. Current opinion in cell biology. 2023. 85. 102249-102249
  • Tsuyoshi Hirashima, Naoya Hino, Kazuhiro Aoki, Michiyuki Matsuda. Stretching the limits of extracellular signal-related kinase (ERK) signaling - Cell mechanosensing to ERK activation. Current opinion in cell biology. 2023. 84. 102217-102217
  • Daniel Boocock, Tsuyoshi Hirashima, Edouard Hannezo. Interplay between Mechanochemical Patterning and Glassy Dynamics in Cellular Monolayers. PRX Life. 2023. 1. 1
  • Veronica Lee Xi Min, Barry T Hinton, Tsuyoshi Hirashima. Collective cell dynamics and luminal fluid flow in the epididymis: A mechanobiological perspective. Andrology. 2023
ｍore...
MISC (21)：
  • 日野直也, 平島剛志. 力学-生化学シグナルの時空間パターン形成と集団遊走. 生物物理. 2024. 64. 2
  • 平島剛志. 巻頭言:スタンダード. 日本細胞生物学会誌. 2023
  • 平島剛志. 新しい研究室の紹介 【日本メカノバイオロジー学会】会誌 Vol.2 -2023. 7. 30-. 日本メカノバイオロジー学会誌. 2023
  • 平島剛志. シンガポール便り -キャリアパス-. 学術変革領域「多細胞生命自律性」ニュースレター. 2023. 2. 1
  • Edouard Hannezo, Tsuyoshi Hirashima. Cell worlds: meet the microscopists. 2022
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Lectures and oral presentations  (32)：
  • ERK活性を介したメカノ・ケミカルフィードバック制御による肺上皮の分岐形態形成
    (第9回定量生物の会年会 2019)
  • Adaptive movement of endothelial cells controlled via physical interaction with an developing epithelial tube
    (京都大学医学研究科 発生・細胞生物・システム生物学コース 2018)
  • ERK活性を介した 細胞集団遊走の数理モデル
    (第3回日本メカノバイオロジー学会年会 2018)
  • Intercellular mechanical wave via intracellular ERK activation during collective cell migration -- experiments and modeling
    (Frontline in DevelopmentalBiology 2018)
  • シグナル活性のライブイメージングと多細胞運動のコンピュテーショナルモデル
    (第15回生物数学の理論とその応用-次世代の数理科学への展開- 2018)
ｍore...
Education (3)：
  • 2008 - 2011 Kyushu University Graduate School of Systems Life Sciences
  • 2006 - 2008 Kyushu University Faculty of Science Department of Biology
  • 2002 - 2006 Kyushu University Faculty of Science Department of Biology
Professional career (1)：
  • Ph. D. (Kyushu University)
Work history (11)：
  • 2022/06 - 現在 National University of Singapore Department of Physiology Research Assistant Professor
  • 2022/06 - 現在 National University of Singapore Mechanobiology Institute Principal Investigator
  • 2021/01 - 2022/06 Kyoto University The Hakubi Center/Graduate School of Biostudies Program-specific Associate Professor
  • 2019/10 - 2023/03 JST PRESTO
  • 2017/04 - 2020/12 Kyoto University Graduate School of Medicine Lecturer
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Committee career (7)：
  • 2022 - 現在 Journal of Theoretical Biology Editorial Board
  • 2021/01 - 現在 JSCB Editorial Board
  • 2021/01 - 現在 BSJ expert advisor "C27 Development"
  • 2018/06 - 現在 JSCB Delegate
  • 2019/04 - 2022/03 NISTEP expert examination committee
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Awards (2)：
  • 2023/04 - 文部科学省 若手科学者賞 多細胞組織の形態形成に関するメカノバイオロジーの研究
  • 2017/09 - The Biophysical Society of Japan The BSJ Award for Young Researchers
Association Membership(s) (5)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR MATHEATICAL BIOLOGY ,  JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS
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