Fukuda Akihisa

Affiliation and department：

Research field (1)： Gastroenterology

Research theme for competitive and other funds (7)：

2019 - 2023 浸潤性膵癌形成後の維持・進行におけるクロマチン制御因子の機能とその分子機構の解明
2017 - 2020 Therapeutic strategy against gastrointestinal cancer by utilizing cancer hierarchy
2016 - 2019 The functional role of chromatin remodeling regualtor Arid11a in pancreatic cancer
2014 - 2017 Anti-cancer therapies baesd on novel cancer stem cell-specific factors
2013 - 2016 The functional role of chromatin remodeling regualtor Brg1 in pancreatic cancer

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Papers (104)：

Sho Matsuyama, Akihisa Fukuda, Atsushi Matsumoto, Hidetaka Eguchi, Taro Ueo, Masaya Ohana, Hiroshi Seno. Sporadic gastric juvenile polyposis with a novel SMAD4 nonsense mutation in a mosaic pattern. Clinical Journal of Gastroenterology. 2023
Toshihiko Masui, Kazuyuki Nagai, Takayuki Anazawa, Yosuke Kasai, Akitada Yogo, Michio Yoshimura, Takashi Mizowaki, Norimitsu Uza, Akihisa Fukuda, Shigemi Matsumoto, et al. Safety and efficacy of neoadjuvant chemoradiotherapy with moderately hypofractionated intensity-modulated radiotherapy for resectable pancreatic cancer: A prospective, open-label, phase II study. Cancer medicine. 2023. 12. 18. 18611-18621
Mio Namikawa, Akihisa Fukuda, Kenta Mizukoshi, Kosuke Iwane, Munenori Kawai, Go Yamakawa, Mayuki Omatsu, Makoto Sono, Tomonori Masuda, Osamu Araki, et al. Simultaneous activation of Kras-Akt and Notch pathways induces extrahepatic biliary cancer via the mTORC1 pathway. The Journal of pathology. 2023. 260. 4. 478-492
Osamu Araki, Motoyuki Tsuda, Mayuki Omatsu, Mio Namikawa, Makoto Sono, Yuichi Fukunaga, Tomonori Masuda, Takaaki Yoshikawa, Munemasa Nagao, Satoshi Ogawa, et al. Brg1 controls stemness and metastasis of pancreatic cancer through regulating hypoxia pathway. Oncogene. 2023. 42. 26. 2139-2152
Naoki Aoyama, Tetsuro Inokuma, Yuki Nakanishi, Akihisa Fukuda. Pancreatic metastasis from lung adenocarcinoma. Journal of general and family medicine. 2023. 24. 3. 192-193

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MISC (123)：

山川剛, 福田晃久, 岩根康祐, 河相宗矩, 尾松万悠紀, 並川実桜, 薗誠, 益田朋典, 荒木理, 長尾宗政, et al. ARID1A has opposite functions in the conventional and serrated pathways in colon tumorigenesis. 日本癌学会学術総会抄録集(Web). 2023. 82nd
長尾宗政, 並川実桜, 水越健太, 中山真之介, 平松由紀子, 丸野貴久, 中西祐貴, 福田晃久, 妹尾浩. The functional role of Kras, p53, Wnt and Notch pathways in the tumorigenesis of extrahepatic biliary system. 日本癌学会学術総会抄録集(Web). 2023. 82nd
尾松万悠紀, 中西祐貴, 水越健太, 岩根康祐, 河相宗矩, 山川剛, 薗誠, 益田朋典, 長尾宗政, 丸野貴久, et al. THBS1 contributes to the creation of immunosuppressive microenvironment and promotes metastasis in colorectal cancer. 日本癌学会学術総会抄録集(Web). 2023. 82nd
河相宗矩, 福田晃久, 中西祐貴, 平松由紀子, 薗誠, 益田朋典, 尾松万悠紀, 並川実桜, 山川剛, 岩根康祐, et al. PBRM1/VIMENTIN axis is a critical determinant for tumor grade and metastasis in Pancreatic cancer. 日本癌学会学術総会抄録集(Web). 2023. 82nd
益田朋典, 福田晃久, 薗誠, 河相宗矩, 山川剛, 長尾宗政, 平松由紀子, 丸野貴久, 中西祐貴, 松崎朋子, et al. RECK blocks pancreatic cancer formation, epithelial-mesenchymal transition and metastasis by regulating MMPs/E-cadherin. 日本癌学会学術総会抄録集(Web). 2023. 82nd

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Books (16)：

日本臨床別冊膵臓症候群(第3版)幹細胞,分化制御と膵発生異常 (迷入膵,膵内副脾を含む).
日本臨床 2021
京都大学医学部附属病院における胆膵疾患に対するユニット治療 -統一した診療と集学的治療への対応
胆と膵・医学図書出版 2021
実験医学カレントトピックス: 細胞系譜解析とライブイメージングによる膵癌幹細胞の動態の可視化
2021
肝胆膵 2019年4月号: 膵発癌におけるクロマチンリモデリング因子の役割.
2019
日本から発信されたサイエンス: Arid1aはSox9の発現制御を介して腸幹細胞維持に必須である. 消化器病学サイエンス
消化器病学サイエンス 2019

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Lectures and oral presentations (5)：

慢性膵炎の診断と治療
(京都消化器医会定例学術講演会 2020)
The Mechanism of Acinar Cell-derived Pancreatic Tumorigenesis.
(The 50th American Pancreatic Association Annual meeting. Maui, USA. 2019)
膵癌の発生におけるクロマチンリモデリング因子の役割
(第2回Gplus 2017)
Chromatin remodeling regulator Brg1 inhibits IPMN and IPMN-derived pancreatic cancer formation.
(2016)
The role of chromatin regulator Brg1 in pancreatic tumorigenesis
(2013)

Work history (1)：

Kyoto University

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