Toyomoto Masayasu

Affiliation and department：

Research field (1)： Applied molecular and cellular biology

Research theme for competitive and other funds (1)：

2022 - 2025 肺線維化機構の解明と治療標的分子の同定

Papers (9)：

Shintaro Maeda, Yuki Shiimura, Hidetsugu Asada, Kunio Hirata, Fangjia Luo, Eriko Nango, Nobuo Tanaka, Masayasu Toyomoto, Asuka Inoue, Junken Aoki, et al. Endogenous agonist-bound S1PR3 structure reveals determinants of G protein-subtype bias. Science advances. 2021. 7. 24
Shuhei Kanagaki, Takahiro Suezawa, Keita Moriguchi, Kazuhisa Nakao, Masayasu Toyomoto, Yuki Yamamoto, Koji Murakami, Masatoshi Hagiwara, Shimpei Gotoh. Hydroxypropyl Cyclodextrin Improves Amiodarone-induced Aberrant Lipid Homeostasis of Alveolar Cells. American journal of respiratory cell and molecular biology. 2021. 64. 4. 504-514
Masayasu Toyomoto, Asuka Inoue, Kei Iida, Masatsugu Denawa, Isao Kii, Francois Marie Ngako Kadji, Takayuki Kishi, Dohyun Im, Tatsuro Shimamura, Hiroshi Onogi, et al. S1PR3-G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation. Cell chemical biology. 2021. 28. 8. 1132-1144
Hiroaki Fuji, Saori Ohmae, Naruto Noma, Masatoshi Takeiri, Hideto Yasutomi, Kazuya Izumi, Moe Ito, Masayasu Toyomoto, Soichiro Iwaki, Kenji Takemoto, et al. Necrostatin-7 suppresses RANK-NFATc1 signaling and attenuates macrophage to osteoclast differentiation. Biochemical and biophysical research communications. 2018. 503. 2. 544-549
Yukiya Sako, Kensuke Ninomiya, Yukiko Okuno, Masayasu Toyomoto, Atsushi Nishida, Yuka Koike, Kenji Ohe, Isao Kii, Suguru Yoshida, Naohiro Hashimoto, et al. Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy. SCIENTIFIC REPORTS. 2017. 7. 46126

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MISC (5)：

豊本雅靖, 豊本雅靖, 栗原崇, 中川貴之, 井上飛鳥, 木村亮, 喜井勲, 喜井勲, 澤田照夫, 澤田照夫, et al. 非オピオイド鎮痛薬の創製. 鎮痛薬・オピオイドペプチドシンポジウムプログラム・抄録集. 2021. 40th
佐古有季哉, 二宮賢介, 奥野友紀子, 豊本雅靖, 西田篤史, 小池悠華, 大江賢治, 喜井勲, 吉田優, 橋本有弘, et al. Duchenne型筋ジストロフィーに対して変異ジストロフィンエキソンのスキッピング誘導活性を有する経口投与可能な新規CLK1阻害剤の開発. 生命科学系学会合同年次大会. 2017. 2017年度. [2P-1437]
豊本雅靖, 井上飛鳥, 飯田慶, 出縄政嗣, 喜井勲, 林佳子, 岸貴之, 小野木博, 吉田優, 細谷孝充, et al. がん細胞の代謝がもたらす組織微小環境を標的にしたがん治療. 生命科学系学会合同年次大会. 2017. 2017年度. [3AT25-1419)]
川元大輔, 喜井勲, 豊本雅靖, 朝田俊秀, 吉村惠, 萩原正敏, 宮田篤郎, 栗原崇. 炎症性疼痛モデルマウスに対する新規カゼインキナーゼ阻害薬の抗侵害効果. 日本薬理学雑誌. 2013. 141. 3. 38P-38P
Yoshinori Nonomura, Masayasu Toyomoto, Tosiniro Nanki, Nobuyuki Miyasaka, Hitoshi Kohsaka. Hypoxia overcomes contact-dependent proliferative inhibition of rheumatoid synovial fibroblasts by downregulating N-cadherin and subsequent P27(Kip1) expression. ARTHRITIS AND RHEUMATISM. 2006. 54. 9. S212-S212

Professional career (1)：

博士(医学) (東京医科歯科大学)

Work history (1)：

Kyoto University

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