2017 - 2019 Technology Integration from Three Countries to Develop Nanoparticle-based Transcription Factor Mimics and Reconstruct Articular Cartilage Components
2017 - 2017 Development of nature-inspired smart transcription factor mimicking anti-obesity function of a cellular energy activator.
2012 - 2017 Control and elucidation of gene expression at a molecular level
2014 - 2015 Next-generation transcriptional activators for direct differentiation
2014 - 2015 Nature-inspired small molecules for regulation of therapeutically important genes
2012 - 2014 Development of programmable small molecules capable of switching ON the transcriptional machinery of pluripotency genes.
2011 - 2012 Development of artificial genetic switches.
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Papers (104)：
Dan Bai, Reihane Ziadlou, Thangavel Vaijayanthi, Subramani Karthikeyan, Shanmugavel Chinnathambi, Anutthaman Parthasarathy, Li Cai, Marie-Charlotte Brüggen, Hiroshi Sugiyama, Ganesh N. Pandian. Nucleic acid-based small molecules as targeted transcription therapeutics for immunoregulation. Allergy. 2023
Thangavel Vaijayanthi, Ganesh N. Pandian, Hiroshi Sugiyama. Pyrrole-Imidazole Polyamides - A Frontrunner in Nucleic Acid-Based Small Molecule Drugs. Advanced Therapeutics. 2023
Rupavarshini, M., Karthikeyan, S., An, h, S., Ramamoorthi, A., Ramakrishnamurthy, S., Bharanidharan, G., Aruna, P., Mangaiyarkarasi, R., Chinnathambi, S., et al. A biophysical approach of cytarabine anticancer drug insights into human serum albumin and checkpoint kinase 1. Results in Chemistry. 2023. 5
Vinodh J. Sahayasheela, Zutao Yu, Takuya Hidaka, Ganesh N. Pandian, Hiroshi Sugiyama. Mitochondria and G-quadruplex evolution: an intertwined relationship. Trends in Genetics. 2023. 39. 1. 15-30
Seithikurippu R. Pandi-Perumal, Velayudhan Mohan Kumar, Namasivayam Ganesh Pandian, Joop T. de Jong, Sudalaikannu Andiappan, Alexandru Corlateanu, Arehally Marappa Mahalaksmi, Saravana Babu Chidambaram, Ramasamy Rajesh Kumar, Chellamuthu Ramasubramanian, et al. Scientists Against War: A Plea to World Leaders for Better Governance. Sleep and Vigilance. 2022. 6. 1
Sequence-specific control of mitochondrial gene transcription using programmable synthetic gene switches called MITO-PIPs
Methods in Molecular Biology, Springer Protocols. Mitochondrial Medicine, 2nd edition, V. Weissig, M. Edeas, Editors. Humana Press, Springer New York Heidelberg Dordrecht London 2020
Synthetic strategies to identify and regulate noncoding RNAs in LONG NONCODING RNAs: Structures and Functions
Springer Japan 2015
Targeted editing of therapeutic genes using DNA-based transcriptional activators: Scope and Challenges in Chemical Biology of Nucleic Acids
Springer Berlin Heidelberg 2014
Designing biomimicking synthetic transcription factors for therapeutic gene modulation
Springer
Lectures and oral presentations (21)：
Programming synthetic molecular codes for bioengineering
(The Korean Society of Biotechnology and Bioengineering 2018)
Designer molecule to target and silence mitochondrial gene transcription
(8th World congress on Targeting Mitochondria, Berlin 2017)
Nature-inspired smart genetic switches,
(7th Indian JSPS Alumni Association (IJAA) International Conference on Science and Technology: Future Challenges and Solutions (STFCS-2016) 2016)
Therapeutic gene modulation using DNA-based transcriptional activators
(Asian International Symposium -Medicinal Chemistry in The 95th Annual Meeting of The Chemical Society of Japan 2015)
Therapeutic gene modulation using DNA-based transcriptional activators,
(Asian International Symposium -Medicinal Chemistry in The 95th Annual Meeting of The Chemical Society of Japan 2015)
