Rchr
J-GLOBAL ID：201501004840280625
Update date: Apr. 22, 2024
Yokota Takashi
ヨコタ タカシ | Yokota Takashi
Affiliation and department：
Job title：
Senior Lecturer
Homepage URL (1)：
https://kaken.nii.ac.jp/d/r/90374321.ja.html
Research field (3)：
Biological, health, and medical informatics
, Cardiology
, Sports science
Research keywords (10)：
Hypertension
, ICT
, Digital health
, Sports medicine
, Exercise physiology
, Heart failure
, Mitochondria
, Gut microbiota
, Diabetes
, Oxidative stress
Research theme for competitive and other funds (16)：
- 2022 - 2025 心房細動の病態進行における心臓周囲脂肪ミトコンドリア機能の役割
- 2021 - 2024 末梢血単核球ミトコンドリア機能を筋ジストロフィーの重症度評価・治療に応用する。
- 2021 - 2024 Development of early detection method for adriamycin-induced cardiomyopathy based on the immunosenescence
- 2021 - 2024 マイオカインによる老化進展制御機構の解明
- 2021 - 2024 The study for prevention of cardiovascular disease by machine learning model using personal health records
- 2018 - 2024 Role of alpha-defensins derived from the small intestine and gut microbiota in heart failure
- 2018 - 2022 Impact of myocardial fibrosis on exercise capacity in heart failure with preserved ejection fraction
- 2015 - 2022 Center of Innovation Program from the Japan Science and Technology Agency (JPMJCE1301)
- 2018 - 2021 Study on the mechanism of regulation of mitochondrial function by brain-derived neurotrophic factor
- 2017 - 2020 The role of protein lysine-acetlation in congenital heart disease
- 2018 - 2020 Study for prevention of hypertensive disease progression using self-care
- 2015 - 2018 Effects of skeletal muscle ischemic preconditioning for fatigability and damage protection
- 2015 - 2018 Role of epicardial adipose tissue mitochondria in cardiovascular disease
- 2014 - 2017 The role of mitoNEET on the regulation of mitochondrial function in skeletal muscle failure
- 2015 - 2017 Study for Development and Verification of Telemedicine for Stroke and Cardiovascular Disease
- 2011 - 2013 Resistance training with blood flow restriction: from basic physiological study to creative clinical application
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Papers (106)：
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Takashi Yokota. Skeletal muscle mitochondria: A potential target for postmenopausal hormone replacement therapy. Acta Physiologica. 2024. e14149
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Hiroyuki Natsui, Masaya Watanabe, Takashi Yokota, Satonori Tsuneta, Yoshizuki Fumoto, Haruka Handa, Matsushima Shouji, Jiro Koya, Kotaro Nishino, Daishiro Tatsuta, et al. Influence of epicardial adipose tissue inflammation and adipocyte size on postoperative atrial fibrillation in patients after cardiovascular surgery. Physiological Reports. 2024. 12. 6. e15957
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Koichi Okita, Masashi Omokawa, Shingo Takada, Tomoyasu Kadoguchi, Noriteru Morita, Takashi Yokota. Muscular stress is equal when resistance exercise with blood flow restriction is matched in total work volume: A cross-sectional, cross-over study. Acta Physiologica. 2024. 240. 3. e14097
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Takashi Yokota, Arata Fukushima, Miyuki Tsuchihashi-Makaya, Takahiro Abe, Shingo Takada, Takaaki Furihata, Naoki Ishimori, Takeo Fujino, Shintaro Kinugawa, Masayuki Ohta, et al. The AppCare-HF randomized clinical trial: a feasibility study of a novel self-care support mobile app for individuals with chronic heart failure. European Heart Journal - Digital Health. 2023. 4. 4. 325-336
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Ryosuke Shirakawa, Takayuki Nakajima, Aya Yoshimura, Yukako Kawahara, Chieko Orito, Miwako Yamane, Haruka Handa, Shingo Takada, Takaaki Furihata, Arata Fukushima, et al. Enhanced mitochondrial oxidative metabolism in peripheral blood mononuclear cells is associated with fatty liver in obese young adults. Scientific Reports. 2023. 13. 1. 5203-5203
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MISC (198)：
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山内 裕貴, 中村 昭伸, 横田 卓, 高橋 清彦, 川田 晋一朗, 土田 和久, 大森 一乃, 野本 博司, 亀田 啓, 曹 圭龍, et al. SGLT2阻害薬はミトコンドリア機能の改善を介し膵β細胞量・機能を保護する. 日本内分泌学会雑誌. 2022. 98. 1. 361-361
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Suppression of Mitochondrial Oxidative Stress and Atrial Fibrillation Inducibility by SGLT2 Inhibitors in Diabetic Rats. 2022. 84
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Takashi Yokota. Future of Heart Failure Treatment and Cardiac Rehabilitation. 2021. 1238. 40-43
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Yuki Yamauchi, Akinobu Nakamura, Takashi Yokota, Kiyohiko Takahashi, Shinichiro Kawata, Kazuhisa Tsuchida, Kazuno Omori, Hiroshi Nomoto, Hiraku Kameda, Kyuyong Cho, et al. Improved Mitochondria! Function by Luseogliflozin Prevents Pancreatic Beta-Cell Damage. DIABETES. 2021. 70
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山内 裕貴, 中村 昭伸, 横田 卓, 高橋 清彦, 川田 晋一朗, 土田 和久, 大森 一乃, 野本 博司, 亀田 啓, 曹 圭龍, et al. SGLT2阻害薬はミトコンドリア機能の改善を介し膵β細胞を保護する. 糖尿病. 2021. 64. Suppl.1. 6-6
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Patents (1)：
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Method for evaluating pathology of cardiac failure
Lectures and oral presentations (63)：
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Brain-derived neurotrophic factor: A key molecule to regulate skeletal muscle function and exercise capacity in heart failure
(87th Japanese Circulation Society Scientific Sessions (JCS2023) 2023)
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循環器疾患・糖尿病診療における デジタルヘルスの活用
(Hokkaido GLP-1 Conference 2022)
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Use-case of real world data
(2022)
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心臓リハビリテーションとCPX (心肺運動負荷検査)
(なの花アカデミーサテライト研修会 2021)
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新しい医療連携のあり方: 医療連携とデジタルヘルスの活用
(医療連携を見据えた糖尿病治療~循環器内科から見た糖尿病治療~ 2021)
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Education (2)：
- 2005 - 2008 Hokkaido University Graduate School of Medicine PhD course
- 1992 - 1998 MD, Hokkaido University
Professional career (1)：
- PhD (Hokkaido University)
Work history (6)：
- 2021/04 - 現在 Hokkaido University Hospital Institute of Health Science Innovation for Medical Care Senior Lecturer
- 2019/04 - 2021/03 Hokkaido University Hospital Clinical Research and Medical Innovation Center Senior lecturer
- 2013 - 2019/03 Hokkaido University Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine Assistant Professor
- 2013/09 - 2018/08 Hokkaido University Health Care Center Assistant Professor
- 2011 - 2013 University of Copenhagen Center for Healthy Aging, Department of Biomedical Sciences Post doc
- 2009/11 - 2011 Hokkaido University, Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Assistant Professor
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Awards (6)：
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