Yoshihara Masahito

ヨシハラマサヒト | Yoshihara Masahito

Affiliation and department：
Job title： Associate Professor
Other affiliations (3)：

Chiba University Department of Artificial Intelligence Medicine, Graduate School of Medicine Associate Professor
Karolinska Institutet Department of Biosciences and Nutrition Visiting Researcher
Osaka University Premium Research Institute for Human Metaverse Medicine (PRIMe) Specially Appointed Professor

Homepage URL (2)： https://www.cn.chiba-u.jp/researcher/yoshihara_masahito/ , https://cn.chiba-u.jp/en/researcher/yoshihara_masahito/

Research field (5)： Systems genomics , Biological, health, and medical informatics , Genomics , Ophthalmology , Molecular biology

Research keywords (5)： induced pluripotent stem cells , Stem cells , regenerative medicine , Transcriptome , Bioinformatics

Research theme for competitive and other funds (7)：

2023 - 2026 遺伝子治療実現に向けたヒト黄斑オルガノイドの開発
2023 - 2025 高深度プロテオーム解析による増殖性硝子体網膜症の病態解明と治療標的探索
2022 - 2025 フックス角膜内皮ジストロフィーの診療エビデンス創出のための研究
2022 - 2024 ヒト神経分化モデルにおける網羅的エンハンサー制御アトラスから迫る病態解明
2019 - 2021 Generation of human early embryo-like stem cells for regenerative medicine

Show all

Papers (42)：

Andrea Coschiera, Masahito Yoshihara, Gilbert Lauter, Sini Ezer, Mariangela Pucci, Haonan Li, Alan Kavšek, Christian G Riedel, Juha Kere, Peter Swoboda. Primary cilia promote the differentiation of human neurons through the WNT signaling pathway. BMC biology. 2024. 22. 1. 48-48
Sayo Maeno, Yoshinori Oie, Ryota Koto, Nozomi Nishida, Arisa Yamashita, Michika Yoshioka, Chifune Kai, Takeshi Soma, Shizuka Koh, Masahito Yoshihara, et al. Comparison of Scheimpflug and Anterior Segment Optical Coherence Tomography Imaging Parameters for Japanese Patients With Fuchs Endothelial Corneal Dystrophy With and Without TCF4 Repeat Expansions. Cornea. 2024
Julia E. Niskanen, Åsa Ohlsson, Ingrid Ljungvall, Michaela Drögemüller, Robert F. Ernst, Dennis Dooijes, Hanneke W. M. van Deutekom, J. Peter van Tintelen, Christian J. B. Snijders Blok, Marion van Vugt, et al. Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human. Genome Medicine. 2023. 15. 1
Masahito Yoshihara, Juha Kere. Transcriptomic differences between human 8-cell-like cells reprogrammed with different methods. Stem cell reports. 2023. 18. 8. 1621-1628
Kayoko Hosaka, Chenchen Wang, Shiyue Zhang, Xue Lv, Takahiro Seki, Yin Zhang, Xu Jing, Jieyu Wu, Qiqiao Du, Xingkang He, et al. Perivascular localized cells commit erythropoiesis in PDGF-B-expressing solid tumors. Cancer communications (London, England). 2023. 43. 6. 637-660

ｍore...

MISC (7)：

Masahito Yoshihara. Towards A Better Understanding of Early Human Embryonic Development. CHIBA UNIVERSITY : Press release. 2023
吉原正仁. ES細胞よりもヒトの受精卵に近い段階の初期胚様細胞を効率よく作製~ヒトの初期発生のメカニズムのさらなる理解へ前進~. 千葉大学:プレスリリース. 2022
吉原正仁, 村川泰裕, 林崎良英, 安倍真澄, 西田幸二. iPS細胞におけるゲノム変異の解明 -iPS細胞樹立時に生じるゲノム変異のホットスポットを同定-. 理化学研究所:プレスリリース. 2017
YOSHIHARA MASAHITO. Commentary: Lens regeneration using endogenous stem cells for infant cataracts. 2016. 15. 3. 300
Masahito Yoshihara, Hideya Kawaji, Kohji Nishida. Discovery of molecular markers to discriminate corneal endothelial cells in the human body. biomedcircus. 2015. 31

ｍore...

Patents (2)：

CORNEAL ENDOTHELIAL CELL MARKER AND UTILIZATION THEREOF
Corneal endothelial cell marker

Books (7)：

ゲノム編集の最新技術と医薬品・遺伝子治療・農業・水畜産物・有用物質生産への活用
技術情報協会 2023 ISBN:9784861049781
Current Topics in iPSCs Technology
Academic Press / Elsevier 2022 ISBN:9780323998925
再生医療の開発戦略と最新研究事例集
技術情報協会 2019 ISBN:9784861047374
遺伝統計学と疾患ゲノムデータ解析 - 病態解明から個別化医療,ゲノム創薬まで -
メディカルドゥ 2018 ISBN:9784944157631
実験医学別冊最強のステップUPシリーズシングルセル解析プロトコールわかる!使える! 1細胞特有の実験のコツから最新の応用まで.
羊土社 2017 ISBN:9784758122344

ｍore...

Lectures and oral presentations (30)：

ヒト8細胞期胚様細胞(8CLCs)の作製およびトランスクリプトーム比較解析
(幹細胞を用いた化学物質リスク情報共有化コンソーシアム第5回研究会 2023)
Transcriptomic differences between human 8-cell-like cells
(NGS EXPO 2023 2023)
新規初期化因子によるヒト初期胚様幹細胞の作製
(アステラス病態代謝研究会第53回研究報告会 2023)
Application of transcriptomic approaches for the treatment of corneal disorders
(The 127th Annual Meeting of the Japanese Ophthalmological Society 2023)
フックス角膜内皮ジストロフィにおけるTCF4 遺伝子のリピート伸長と表現型の解析
(角膜カンファランス2023 第47回日本角膜学会・第39回日本角膜移植学会 2023)

ｍore...

Education (3)：

2013 - 2017 Osaka University Graduate School of Medicine
2004 - 2010 Osaka University Faculty of Medicine
2001 - 2004 Rakunan High School

Professional career (2)：

M.D. (Osaka University)
Ph.D. (Osaka University)

Work history (12)：

2023/12 - 現在 Osaka University Premium Research Institute for Human Metaverse Medicine (PRIMe) Specially Appointed Professor
2022/04 - 現在 Chiba University Institute for Advanced Academic Research Associate Professor
2022/04 - 現在 Chiba University Graduate School of Medicine Department of Artificial Intelligence Medicine Associate Professor
2022/04 - 現在 Karolinska Institutet Department of Biosciences and Nutrition Visiting Researcher
2021/08 - 2022/03 Karolinska Institutet Department of Biosciences and Nutrition Senior Researcher

Show all

Awards (2)：

2015/09 - RIKEN SUMMER SCHOOL 2015 POSTER AWARD MEDICAL SCIENCE PRIZE
2010/03 - Osaka University Kusumoto Award (The top graduate)

Association Membership(s) (6)：

JAPANESE OPHTHALMOLOGICAL SOCIETY , JAPANESE SOCIETY FOR BIOINFORMATICS , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , 日本角膜学会 , Japanese Association for Medical Artificial Intelligence , International Society for Stem Cell Research (ISSCR)

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page