Naganuma Fumito

ナガヌマフミト | Naganuma Fumito

Affiliation and department：
Homepage URL (1)： https://kaken.nii.ac.jp/d/p/14J07936.ja.html

Research field (2)： Neuroscience - general , Pharmacology

Research keywords (7)：神経ペプチド , Sleep , 睡眠 , Comprihensive Brain Science Network , histamine N-methyltransferase , monoamine transporter , Histamine

Research theme for competitive and other funds (8)：

2023 - 2027 中枢神経系脆弱性と全身麻酔に関連した周術期認知機能障害の神経病理解析
2022 - 2025 REM睡眠による異常タンパク質の排出増加はアルツハイマー病を治療できるか?
2020 - 2023 吸入麻酔薬の意識消失作用におけるニューロテンシン神経系の役割
2019 - 2021 Importance of lateral hypothalamic neurotensinergic neurons in wake maintenance
2018 - 2020 ヒスタミン神経系による攻撃性制御機構の解明

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Papers (33)：

Fumito Naganuma, Daiki Murata, Marie Inoue, Yuri Maehori, Ryuichi Harada, Shozo Furumoto, Yukitsuka Kudo, Tadaho Nakamura, Nobuyuki Okamura. A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer's Disease Mouse Model. Molecular imaging and biology. 2023
Ryota Kobayashi, Tadaho Nakamura, Fumito Naganuma, Ryuichi Harada, Daichi Morioka, Masafumi Kanoto, Shozo Furumoto, Yukitsuka Kudo, Takanobu Kabasawa, Koichi Otani, et al. In vivo [18F]THK-5351 imaging detected reactive astrogliosis in argyrophilic grain disease with comorbid pathology: A clinicopathological study. Journal of neuropathology and experimental neurology. 2023. 82. 5. 427-437
Tadaho Nakamura, Fumito Naganuma, Uta Kudomi, Sueji Roh, Kazuhiko Yanai, Takeo Yoshikawa. Oral histidine intake improves working memory through the activation of histaminergic nervous system in mice. Biochemical and biophysical research communications. 2022. 609. 141-148
Rina Otsuka, Fumito Naganuma, Tadaho Nakamura, Hideki Miwa, Rumi Nakayama-Naono, Takuro Matsuzawa, Yurika Komatsu, Yuki Sato, Yuna Takahashi, Haruna Tatsuoka-Kitano, et al. Contribution of astrocytic histamine N-methyltransferase to histamine clearance and brain function in mice. Neuropharmacology. 2022. 212. 109065-109065
Fumito Naganuma, Tadaho Nakamura, Hiroshi Kuroyanagi, Masato Tanaka, Takeo Yoshikawa, Kazuhiko Yanai, Nobuyuki Okamura. Chemogenetic modulation of histaminergic neurons in the tuberomamillary nucleus alters territorial aggression and wakefulness. Scientific reports. 2021. 11. 1. 17935-17935

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MISC (96)：

中村正帆, 長沼史登, 田中聖人, 井上まり絵, 直野留美, 吉川雄朗, 岡村信行. 扁桃体中心核ニューロテンシン神経細胞の睡眠覚醒サイクルにおける役割の検討. 応用薬理. 2022. 102. 5-6. 128-128
Naganuma Fumito, Nakamura Tadaho, Vetrivelan Ramalingam, Yoshikawa Takeo, Okamura Nobuyuki. Neurotensinergic neurons in the lateral hypothalamus are important for physiological sleep-wake cycle. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 3-B-P-185
Nakamura Tadaho, Kimura Takeshi, Naganuma Fumito, Yoshikawa Takeo, Okamura Nobuyuki, Yanagita Toshihiko. Assessment of learning achievement using self-assessment rubric in the role-play for pharmacological education. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 4-B-O13-6
吉川雄朗, 小松由梨香, 松澤健介, 大塚里奈, 長沼史登, 長沼史登, 中村正帆, 中村正帆, 谷内一彦. 脳内ヒスタミン代謝酵素の機能解析. 日本ヒスタミン学会プログラム・講演要旨集. 2022. 23rd (CD-ROM)
中村正帆, 長沼史登, 黒柳浩志, 田中聖人, 吉川雄朗, 谷内一彦, 岡村信行. ヒスタミン神経細胞特異的な活性変化が攻撃行動と睡眠覚醒サイクルに及ぼす影響. 日本ヒスタミン学会プログラム・講演要旨集. 2022. 23rd (CD-ROM)

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Books (1)：

グッドマン・ギルマン薬理学書 13版
廣川書店 2021

Lectures and oral presentations (137)：

ヒスタミン代謝酵素阻害薬のナルコレプシー治療に対する有効性の検討
(第45回日本睡眠学会・第30回日本時間生物学会学術大会合同大会 2023)
睡眠覚醒に関わるニューロテンシン神経系の役割について
(第36回北海道薬物作用談話会 2023)
Neurotensinergic neurons in the lateral hypothalamus are important for physiological sleep-wake cycle
(2022)
Assessment of learning achievement using self-assessment rubric in the role-play for pharmacological education
(2022)
ヒスタミン代謝酵素阻害剤メトプリンの行動薬理学的検討
(第73回日本薬理学会北部会 2022)

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Education (2)：

2012 - 2016 Tohoku Univ. graduate school of Medicine Ph.D. student
2010 - 2012 Tohoku Univ. graduate school of Medicine Master corse student

Professional career (1)：

博士(医学) (東北大学)

Work history (5)：

2023/07 - 現在北海道大学大学院医学研究院神経薬理学教室
2016/04 - 2023/06 Tohoku Medical and Pharmaceutical Univ. Division of Pharmacology Assistant professor
2016/04 - 2018/09 Beth Israel Deaconess Medical Center (Harvard Medical School) Neurology Post-Doctoral Fellow
2014/04 - 2016/03 Japan Society for the Promotion of Science Research Fellow (DC)
2013/04 - 2016/03 Tohoku Univ. Division For International Advanced Research and Education PhD student

Committee career (2)：

2020/04 - 現在日本薬理学会次世代の会メンバー
2019/04 - 現在日本薬理学会学術評議委員

Awards (19)：

2022/12 - 第96回日本薬理学会年会優秀ポスター賞
2021/06 - Nishinomiya Basic Research Fund, Japan
2017/04 - The Science Research Promotion Fund
2015/09 - 日本神経化学会神経化学教育口演優秀発表賞
2015/05 - ヨーロッパヒスタミン学会奨学賞

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Association Membership(s) (5)：

THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE JAPAN NEUROSCIENCE SOCIETY , THE JAPANESE PHARMACOLOGICAL SOCIETY , 北米神経科学会

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