Rchr
J-GLOBAL ID:201701000583792350
Update date: Apr. 18, 2024
Kato Hideaki
カトウ ヒデアキ | Kato Hideaki
Affiliation and department:
Job title:
准教授
Homepage URL (1):
http://park.itc.u-tokyo.ac.jp/hekato_lab/english_home.html
Research field (3):
Functional biochemistry
, Biophysics
, Structural biochemistry
Research keywords (7):
protein engineering
, オプトジェネティクス
, GPCR
, ロドプシン
, 電子顕微鏡
, X線結晶構造解析
, 構造生物学
Research theme for competitive and other funds (12):
- 2022 - 2027 The analysis of structural dynamics of microbial rhodopsins
- 2022 - 2025 Structural and functional analysis of novel transporter-type rhodopsin
- 2021 - 2025 Manipulation of G12/13 signaling and and drug development strategy
- 2021 - 2024 Neural representation of "Death" (general affairs)
- 2021 - 2024 The engineering of the novel imaging tools for neuromodulators
- 2021 - 2024 酵素型ロドプシン:光でON-OFFする酵素が描く新しい微生物の生き様
- 2021 - 2024 光により操作可能な生命現象の拡張と光遺伝学2.0の創出
- 2019 - 2022 Structural analysis of NTSR1-G-protein complexes
- 2017 - 2021 構造情報を基にした新規チャネル型抑制性光遺伝学ツール開発
- 2016 - 2017 非古典的GPCRであるKDEL受容体の構造機能解析
- 2014 - 2016 β2アドレナリン受容体-アレスチン複合体の構造・機能解析
- 2011 - 2013 X線結晶構造解析に基づく改変型チャネルロドプシンの創出
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Papers (36):
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Seiya Tajima, Yoon Seok Kim, Masahiro Fukuda, YoungJu Jo, Peter Y Wang, Joseph M Paggi, Masatoshi Inoue, Eamon F X Byrne, Koichiro E Kishi, Seiwa Nakamura, et al. Structural basis for ion selectivity in potassium-selective channelrhodopsins. Cell. 2023
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Koichiro E Kishi, Hideaki E Kato. Pump-like channelrhodopsins: Not just bridging the gap between ion pumps and ion channels. Current opinion in structural biology. 2023. 79. 102562-102562
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Kazuhiro Kobayashi, Kouki Kawakami, Tsukasa Kusakizako, Hirotake Miyauchi, Atsuhiro Tomita, Kan Kobayashi, Wataru Shihoya, Keitaro Yamashita, Tomohiro Nishizawa, Hideaki E Kato, et al. Endogenous ligand recognition and structural transition of a human PTH receptor. Molecular cell. 2022. 82. 18. 3468-3483
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Koichiro E Kishi, Yoon Seok Kim, Masahiro Fukuda, Masatoshi Inoue, Tsukasa Kusakizako, Peter Y Wang, Charu Ramakrishnan, Eamon F X Byrne, Elina Thadhani, Joseph M Paggi, et al. Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine. Cell. 2022
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Naotaka Tsutsumi, Shoji Maeda, Qianhui Qu, Martin Vögele, Kevin M. Jude, Carl-Mikael Suomivuori, Ouliana Panova, Deepa Waghray, Hideaki E. Kato, Andrew Velasco, et al. Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins. Science Advances. 2022. 8. 3
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MISC (23):
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岸孝一郎, 加藤英明. 新しいチャネルロドプシンと光遺伝学. 糖尿病・内分泌代謝科. 2023. 56. 5. 662-668
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Toshiki Matsui, Hideaki Kato. Cryo-EM analysis of dynamic G-protein activation process by neurotensin receptor 1. Journal of Japanese Biochemical Society. 2022. 94. 6. 916-922
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Hideaki Kato. Structural biology of the non-class A GPCRs. CLINICAL NEUROSCIENCE. 2022. 40. 11. 1344-1347
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Hideaki Kato. Structural biology of the class A GPCRs (2). CLINICAL NEUROSCIENCE. 2022. 40. 9. 1052-1054
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Hideaki Kato. Structural biology of the class A GPCRs (1). CLINICAL NEUROSCIENCE. 2022. 40. 8. 923-925
more...
Patents (3):
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Variant Chrmine Proteins Having Accelerated Kinetics and/or Red-Shifted Spectra
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NATIVE CHANNELRHODOPSIN DETECTION KIT
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Light-responsive polypeptides and methods of use thereof
Books (2):
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Optogenetics -Light-Sensing Proteins and Their Applications-
Springer 2015
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オプトジェネティクス-光工学と遺伝学による行動抑制技術の最前線
エヌ・ティー・エス 2013 ISBN:4864690715
Lectures and oral presentations (50):
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Channelrhodopsin research: Bridging structural biology and neuroscience
(Hx/HBP 2024 Spring Initiation Seminar 2024)
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Structural basis for K+ selectivity in channelrhodopsins
(Japan BioEnergetics Group 49th meeting 2023)
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Structural and functional diversity in pump-like cation channelrhodopsins
(NIPS EM Workshop 2023, "Cryo-EM and related techniques" 2023)
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Trends in the development of optogenetic tools using ion-transporting rhodopsins
(16th Retina Research Meeting (RRM) 2023)
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Dynamic recognition and activation of G proteins by the Neurotensin receptor 1
(The 61st Annual Meeting of the Biophysical Society of Japan 2023)
more...
Education (3):
- 2011 - 2014 The University of Tokyo School of Science Department of Biophysics and Biochemistry
- 2009 - 2011 The University of Tokyo School of Science Department of Biophysics and Biochemistry
- 2005 - 2009 The University of Tokyo Faculty of Science
Professional career (1):
- Ph.D. (The University of Tokyo)
Work history (10):
- 2024/02 - 現在 The University of Tokyo Research Center for Advanced Science and Technology Professor
- 2024/02 - 現在 The University of Tokyo Graduate School of Science Department of Biological Sciences Professor(Adjunct)
- 2024/02 - 現在 The University of Tokyo The Graduate School of Engineering Department of Advanced Interdisciplinary Studies Professor(Adjunct)
- 2024/02 - 現在 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences Professor(Adjunct)
- 2020/04 - 2024/01 The University of Tokyo Graduate School of Science Department of Biological Sciences associate professor(Adjunct)
- 2019/04 - 2024/01 The University of Tokyo Department of Life Sciences associate professor
- 2017/10 - 2021/03 PRESTO researcher JST adjanct
- 2019/04 - 2020/03 The University of Tokyo Distinguished researcher
- 2014/05 - 2019/03 Stanford University School of Medicine Postdoctoral fellow
- 2014/04 - 2014/05 The University of Tokyo
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Committee career (5):
- 2023/04 - 現在 日本生物物理学会 代議員
- 2020 - 現在 文部科学省科学技術・学術政策研究所科学技術予測・政策基盤調査研究センター 科学技術専門家ネットワーク・専門調査員
- 2022/04 - 2024/03 日本生物物理学会 「生物物理」誌編集委員
- 2020/04 - 2022/03 日本生物物理学会 分野別専門委員
- 2022 - 2022 19th International Conference on Retinal Proteins (ICRP2022) Local Organizing Committee
Awards (14):
- 2024/04 - Nakatani Foundation Kobe Prize, Young Investigator Awards
- 2020/12 - Shimadzu Foundation Shimadzu Young Researcher Award
- 2020/09 - The Frontier Salon Foundation 10th Frontier Salon Nagase Prize, Special Prize
- 2020/04 - The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, The Young Scientists’ Award
- 2019/12 - MEXT NISTEP The Researchers with Nice Step
- 2016/12 - Inoue Foundation for Science Inoue Research Award for Young Scientists
- 2016/07 - SPring-8 Users Community SPRUC (SPring-8 Users Community) Young Scientist Award
- 2015/09 - The Biophysical Society of Japan The Early Career Award in Biophysics
- 2014/03 - The University of Tokyo University of Tokyo Graduate School of Science President's Award
- 2014/03 - The University of Tokyo University of Tokyo Graduate School of Science Research Award
- 2013/03 - JSPS JSPS Ikushi Prize
- 2012/08 - Merck The Merck Award for Young Biochemistry Researcher
- 2012/06 - Young Scientist Award from Protein Science Society of Japan
- 2008/03 - Elite Science Student Abroad Program (ESSVAP), Faculty of Science, Dean’s Award
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Association Membership(s) (1):
The Biophysical Society of Japan
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