Rchr
J-GLOBAL ID:201701009584156404   Update date: Apr. 13, 2024

Kojima Ryosuke

コジマ リョウスケ | Kojima Ryosuke
Affiliation and department:
Job title: Associate Professor
Homepage URL  (2): https://cbmi.m.u-tokyo.ac.jp/membershttps://scholar.google.com/citations?user=lP4Uu2MAAAAJ&hl=ja
Research field  (6): Chemical biology ,  Biomaterials ,  Biomedical engineering ,  Biochemistry ,  Pharmaceuticals - chemistry and drug development ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (9): Extracellular vesicles ,  Cell-cell communication ,  Bioluminescence Imaging ,  cancer ,  exosome ,  Drug Delivery System ,  Fluorescence imaging ,  Synthetic Biology ,  Chemical Biology
Research theme for competitive and other funds  (15):
  • 2022 - 2028 Research on intracellular degradation focusing on membranous structures
  • 2023 - 2028 DNAイベントレコーダー細胞
  • 2024 - 2027 細胞間コミュニケーションの網羅的記録を基軸とした「適応多様性」の理解
  • 2024 - 2027 細胞表面抗原に応答するレポーター酵素スイッチの創製とがん診断・治療への応用
  • 2023 - 2027 Selective wound healing senolytics targeting senescent cells in wound exudate
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Papers (47):
  • Yugo Kuriki, Mari Sogawa, Toru Komatsu, Minoru Kawatani, Hiroyoshi Fujioka, Kyohhei Fujita, Tasuku Ueno, Kenjiro Hanaoka, Ryosuke Kojima, Rumi Hino, et al. Modular Design Platform for Activatable Fluorescence Probes Targeting Carboxypeptidases Based on ProTide Chemistry. Journal of the American Chemical Society. 2023
  • Koki Kunitake, Tadahaya Mizuno, Kazuki Hattori, Chitose Oneyama, Mako Kamiya, Sadao Ota, Yasuteru Urano, Ryosuke Kojima. Barcoding of small extracellular vesicles with CRISPR-gRNA enables comprehensive, subpopulation-specific analysis of their biogenesis/release regulators. 2023
  • Jingwen Shou, Ayumi Komazawa, Yuusaku Wachi, Minoru Kawatani, Hiroyoshi Fujioka, Spencer John Spratt, Takaha Mizuguchi, Kenichi Oguchi, Hikaru Akaboshi, Fumiaki Obata, et al. Super-resolution vibrational imaging based on photoswitchable Raman probe. Science advances. 2023. 9. 24. eade9118
  • Takafumi Kasai, Kyohhei Fujita, Toru Komatsu, Tasuku Ueno, Ryosuke Kojima, Kenjiro Hanaoka, Yasuteru Urano. Development of near-infrared fluorescence probe for the selective detection of severe hypoxia. ChemRxiv. 2023
  • Hiroyoshi Fujioka, Minoru Kawatani, Spencer John Spratt, Ayumi Komazawa, Yoshihiro Misawa, Jingwen Shou, Takaha Mizuguchi, Hina Kosakamoto, Ryosuke Kojima, Yasuteru Urano, et al. Activatable Raman Probes Utilizing Enzyme-Induced Aggregate Formation for Selective Ex Vivo Imaging. Journal of the American Chemical Society. 2023
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MISC (14):
  • 小嶋良輔, 國武 厚貴. 合成生物学的アプローチが可能とする細胞外小胞の理解と発展的利用. 生化学. 2023. 95. 2. 194-200
  • 小嶋良輔. “Designer EV”の開発の現状と将来展望. 実験医学増刊. 2021. 39. 20
  • Ryosuke Kojima (Editor). Methods in Molecular Biology, Mammalian Cell Engineering. 2021
  • 小嶋良輔. 遺伝子工学的アプローチを利用した エクソソームのエンジニアリングとその応用. 膜. 2020. 2. 62-67
  • 小嶋 良輔. Top Researchers インタビュー. 2019
more...
Patents (2):
  • Library of barcoded extracellular vesicles
  • New NIR-emitting luciferins
Education (3):
  • - 2014 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • - 2009 The University of Tokyo Department of Pharmaceutical Sciences
  • - 2005 Komaba-toho High School
Professional career (1):
  • PhD (The University of Tokyo)
Work history (10):
  • 2022/11 - 現在 Nagoya University, Institute of Nano-Life-Systems, Institutes of Innovation for Future Society Institute of Innovation for Future Society Nano-Life System Visiting Associate Professor
  • 2022/10 - 現在 The University of Tokyo Graduate School of Medicine Associate Professor
  • 2022/04 - 現在 JST FOREST researcher
  • 2020/04 - 2022/10 Nagoya University Institute of Innovation for Future Society Nano-Life System Visiting Assistant Professor
  • 2017/07 - 2022/09 The University of Tokyo Graduate School of Medicine Assistant Professor
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Awards (10):
  • 2023/04 - MEXT Young Scientist Prize
  • 2022/04 - CREST Fine Particles, Young Innovator Award
  • 2019/03 - Human Frontier Science Program (HFSP) Career Development Award,
  • 2018/09 - 12th Bio-Related Chemistry Symposium Best Lectureship Award
  • 2018/06 - 13th Meeting of Japanese Society for Chemical Biology Royal Society of Chemistry Poster Award
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Association Membership(s) (4):
Japanese Society of Chemical Biology ,  The Pharmaceutical Society of Japan ,  The Japanese Biochemical Society ,  Japanese Society for Molecular Imaging
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