Rchr
J-GLOBAL ID:201701011443524021   Update date: Apr. 18, 2024

Ito Koichi

イトウ コウイチ | Ito Koichi
Affiliation and department:
Homepage URL  (1): https://sites.google.com/edu.k.u-tokyo.ac.jp/molgenet/home
Research field  (3): Evolutionary biology ,  Structural biochemistry ,  Functional biochemistry
Research keywords  (25): 構造機能生物学 ,  translational control by ubiquitination ,  metal ion transport ,  cellular magnesium homeostasis ,  membrane transporter ,  molecular evolution ,  ribosome recycling ,  G protein ,  protein synthesis ,  Membrane transport protein ,  RECODING ,  stop codon ,  tRNA ,  RNA biology ,  polypeptide-chain release factor ,  molecular genetics ,  )は、システム工学の考え方や解析手法を生物学に導入し、生命現象をシステムとし ,  synthetic biology ,  translation control ,  molecular genetics of budding yeast ,  molecular genetics of bacterial ,  tRNA mimicry protein ,  translation termination ,  ribosome ,  genetic code
Research theme for competitive and other funds  (21):
  • 2020 - 2024 Study of molecular mechanisms for translation termination and ribosome recycling by eukaryotic ribosome
  • 2020 - 2023 Study of gene regulatory network for cellular magnesium ion homeostasis.
  • 2016 - 2020 Molecular mechanism of membrane proteins regulated by physical stimuli
  • 2016 - 2018 tRNA擬態タンパク質による例外的遺伝暗号認識解読機構の解明
  • 2012 - 2016 Structural basis for molecular mechanisms of membrane transporters
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Papers (95):
  • Hiroshi Otsuka, Kei Endo, Miki Wada, Koichi Ito. Systematic genetic identification of functional domains on collided di-ribosomes responsible for rescue pathways upon translation arrest in Saccharomyces cerevisiae. The FEBS Journal. 2023
  • Miki Wada, Koichi Ito. The CGA codon decoding through tRNA Arg ( ICG ) supply governed by Tad2/Tad3 in Saccharomyces cerevisiae. The FEBS Journal. 2023
  • Tatsuya Niwa, Koki Nakazawa, Kensuke Hoshi, Hisashi Tadakuma, Koichi Ito, Hideki Taguchi. Application of fluorescence correlation spectroscopy to investigate the dynamics of a ribosome-associated trigger factor in Escherichia coli. Front Mol Biosci . 2022. 9
  • Miki Wada, Koichi Ito. Human ABCE1 exhibits temperature-dependent heterologous co-functionality in S. cerevisiae. FEBS Open Bio. 2022
  • Xiaoyu Yang, Natsuko I Kobayashi, Yoshiki Hayashi, Koichi Ito, Yoshitaka Moriwaki, Tohru Terada, Kentaro Shimizu, Motoyuki Hattori, Ren Iwata, Hisashi Suzuki, et al. Mutagenesis Analysis of GMN Motif in Arabidopsis thaliana Mg2+ Transporter MRS2-1. Bioscience, Biotechnology, and Biochemistry. 2022. 86. 7. 870-874
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MISC (32):
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Lectures and oral presentations  (155):
  • Comprehensive NGS-based search for novel factors constituting the molecular network of intracellular magnesium homeostasis
    (2022)
  • A systematic genetic screening toward up-regulating the activity of CrPV IRES-mediated translation in Saccharomyces cerevisiae
    (2022)
  • Analysis of SECIS-Aptamer Riboswitch Designs that Regulate Selenocysteine Incorporation
    (2022)
  • リボソーム再生反応におけるATP加水分解酵素ABCE1の相互作用ドメインの解明
    (第43回日本分子生物学会年会 2020)
  • RNA-タンパク質相互作用を細胞質内で評価する Yeast Casplay System の開発
    (第43回日本分子生物学会年会 2020)
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Education (3):
  • 1988 - 1993 The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry
  • - 1988 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
  • 1984 - The University of Tokyo
Professional career (1):
  • 博士(理学) (東京大学)
Work history (12):
  • 2015/04 - 現在 The University of Tokyo
  • 2012/06 - 2015/03 The University of Tokyo Graduate School of Frontier Sciences, Department of Medical Genome Sciences
  • 2010/04 - 2014/03 東京理科大学 総合研究機構 RNA科学総合研究センター 客員教授
  • 2011/02 - The University of Tokyo Graduate School of Frontier Sciences, Department of Medical Genome Sciences
  • 2006/04 - 2009/03 科学技術振興機構(JST) さきがけ「RNAと生体機能」 研究者(兼任)
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Association Membership(s) (1):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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