Rchr
J-GLOBAL ID：201701016657019040   Update date: Apr. 15, 2024

Suzuki Miho

スズキ ミホ | Suzuki Miho
Affiliation and department：
National Institute for Basic Biology

About National Institute for Basic Biology


Research field  (2)： Molecular biology ,  Evolutionary biology
Research keywords  (4)： ゲノム不安定性 ,  長鎖非翻訳RNA ,  Transcriptional regulation ,  DNA methylation
Research theme for competitive and other funds  (9)：
  • 2023 - 2026 ミスマッチリペア機構欠損に依存しないマイクロサテライト不安定性誘導系の研究
  • 2020 - 2023 がん細胞の複製ストレスを解消する新規lncRNAの機能解明
  • 2016 - 2021 DDS技術を基盤とした革新的がん治療法の開発
  • 2017 - 2020 転写量ノイズを消去し細胞均一性を維持する機構の解明
  • 2014 - 2017 遺伝子転写領域のクロマチン構造とエピジェネティック制御の解明
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Papers (27)：
  • Ryosuke Sonobe, Peng Yang, Miho M. Suzuki, Keiko Shinjo, Kenta Iijima, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka, Hiroaki Kajiyama, Yutaka Kondo. Long noncoding RNA TUG1 promotes cisplatin resistance in ovarian cancer via upregulation of DNA polymerase eta. Cancer Science. 2024
  • Miho M Suzuki, Kenta Iijima, Koichi Ogami, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Xuebing Wang, Yotaro Kitano, Akira Mamiya, Yuji Kibe, et al. TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation. Nature communications. 2023. 14. 1. 4521-4521
  • Ayako Muraoka, Miho Suzuki, Tomonari Hamaguchi, Shinya Watanabe, Kenta Iijima, Yoshiteru Murofushi, Keiko Shinjo, Satoko Osuka, Yumi Hariyama, Mikako Ito, et al. Fusobacterium infection facilitates the development of endometriosis through the phenotypic transition of endometrial fibroblasts. Science Translational Medicine. 2023. 15. 700
  • Kentaro Imai, Takuji Ishimoto, Tomohito Doke, Toshiki Tsuboi, Yu Watanabe, Keisuke Katsushima, Miho Suzuki, Hideto Oishi, Kazuhiro Furuhashi, Yasuhiko Ito, et al. Long non-coding RNA lnc-CHAF1B-3 promotes renal interstitial fibrosis by regulating EMT-related genes in renal proximal tubular cells. Molecular Therapy - Nucleic Acids. 2023. 31. 139-150
  • Yoshihiko Tasaki, Miho Suzuki, Keisuke Katsushima, Keiko Shinjo, Kenta Iijima, Yoshiteru Murofushi, Aya Naiki-Ito, Kazuki Hayashi, Chenjie Qiu, Akiko Takahashi, et al. Cancer-Specific Targeting of Taurine-Upregulated Gene 1 Enhances the Effects of Chemotherapy in Pancreatic Cancer. Cancer Research. 2021. 81. 7. 1654-1666
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MISC (7)：
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Lectures and oral presentations  (8)：
  • Long noncoding RNA TUG1 regulates R-loop resolution and maintains cancer cell proliferation
    (2021)
  • Long noncoding RNA TUG1 regulates R-loop resolution and maintains cancer cell proliferation
    (2021)
  • Long non-coding RNA TUG1 stabilizes replication forks in proximity to nuclear speckles
    (2021)
  • Spatiotemporal Regulation of Long non-coding RNA to propagate Cancer Cells
    (第126回日本解剖学会総会・全国学術集会 2021)
  • Spatiotemporal regulation of replication stress by TUG1 as a prerequisite for ca ncer cell proliferation
    (2020)
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Professional career (1)：
  • 博士(理学) (京都大学)
Work history (9)：
  • 2017/04 - 現在 名古屋大学医学系研究科 腫瘍生物学部門 助教
  • 2014/04 - 2017/03 National Institute for Basic Biology
  • 2013/04 - 2014/03 National Institute for Basic Biology
  • 2012/04 - 2013/03 National Institute for Basic Biology
  • 2009/10 - 2012/03 Institute for Developmental Research, Aichi Human Service Center
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Awards (1)：
  • 2021/11 - The Japanese Biochemical Society JB reviewer award
Association Membership(s) (3)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  日本癌学会 ,  THE JAPANASE SOCIETY FOR EPIGENETICS
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