Research field (2):
Cell biology
, Functional biochemistry
Research keywords (4):
innate immunity
, glycosylation
, organelle
, GPI-anchored protein
Research theme for competitive and other funds (7):
2020 - 2023 核ラミナの機能に必要な、新しい分子の発見
2019 - 2022 Analysis of the mechanism of exacerbation of neurodegeneration by innate immunity
2014 - 2017 Mechanism of glycan change involved in the activation of innate immunity
2012 - 2014 自然炎症の恒常性維持に寄与する糖鎖修飾の解析
2011 - 2013 GPI アンカー修飾は mRNA の局在によって制御されているか
2000 - 2001 顎下腺の唾液分泌刺激における細胞内Ca^<2+>シグナリングの研究
1999 - 2000 顎下腺の唾液分泌刺激における細胞内Ca^<2+>シグナリングの研究
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Papers (32):
Kohei Kawaguchi, Miki Yamamoto-Hino, Satoshi Goto. SPPL3-dependent downregulation of the synthesis of (neo)lacto-series glycosphingolipid is required for the staining of cell surface CD59. Biochemical and Biophysical Research Communications. 2021. 571. 81-87
Kohei Kawaguchi, Miki Yamamoto-Hino, Nina Matsuyama, Emiko Suzuki, Satoshi Goto. Subunits of the GPI transamidase complex localize to the endoplasmic reticulum and nuclear envelope in Drosophila. FEBS Letters. 2021. 595. 7. 960-968
Kohei Kawaguchi, Miki Yamamoto-Hino, Yoshiko Murakami, Taroh Kinoshita, Satoshi Goto. Hrd1-dependent Degradation of the Unassembled PIGK Subunit of the GPI Transamidase Complex. Cell Structure and Function. 2021. 46. 2. 65-71
Miki Yamamoto-Hino, Kohei Kawaguchi, Masaya Ono, Kazuhiro Furukawa, Satoshi Goto. Lamin is essential for nuclear localization of the GPI synthesis enzyme PIG-B and GPI-AP production in Drosophila. Journal of Cell Science. 2020. 133. 6
Kohei Kawaguchi, Tatsuro Sato, Shu Kondo, Miki Yamamoto-Hino, Satoshi Goto. Stability of the transamidase complex catalyzing GPI anchoring of proteins. Biochemical and Biophysical Research Communications. 2019. 512. 3. 584-590
K Mikoshiba, T Furuichi, A Miyawaki, T Michikawa, M Yamamoto-Hino, J Hirota, K Takei, T Inoue, S Kume, M Matsumoto, et al. Role of inositol 1,4,5-trisphosphate (IP3) receptor/Ca2+ signaling in cell function. CHALLENGES FOR NEUROSCIENCE IN THE 21ST CENTURY. 2000. 22. 22. 121-146