Rchr
J-GLOBAL ID：201701020786837660
Update date: Feb. 22, 2024
Shimizu Yoshihiro
シミズ ヨシヒロ | Shimizu Yoshihiro
Affiliation and department：
Homepage URL (1)：
https://sites.google.com/site/labcfps/
Research field (3)：
Applied biofunctional and bioprocess engineering
, Systems genomics
, Molecular biology
Research keywords (5)：
ribosome
, mass spectrometry
, proteome
, cell-free protein synthesis system
, biochemistry
Research theme for competitive and other funds (12)：
- 2022 - 2027 生物班:CO環境で成立する生物圏の解明
- 2020 - 2025 AutoMatter: Toward creation and expansion of programmable micro-active matter
- 2022 - 2024 Development of a method for determining celebral infarction sites by serum omics analysis
- 2020 - 2021 Creation and development of programmable dynamic microparticles "auto-matter"
- 2018 - 2021 Creating a pharmacological evaluation system using a highly sensitive single cell ESI-MS analysis for the development of innovative new drugs.
- 2017 - 2019 Elucidation of higher-order structure of central dogma process by specific and extensive analyses of translational template nucleic acids
- 2015 - 2017 Proteome analysis for low abundant ptoteins
- 2014 - 2017 Development of the self-replicable cell-free protein synthesis system
- 2014 - 2017 State analyses of a cell-free protein synthesis system using ribosome profiling
- 2008 - 2009 人工細胞モデル構築のための基盤技術としての無細胞タンパク質合成システムの構築
- 2007 - 2008 Investigation of the ribosome dynamics generated by trans-translation specific SmpB protein
- 2006 - 2008 Reconstitution of cell-free protein maturation system coupled with translation system.
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Papers (72)：
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Huaqi Tang, Yasmine Abouleila, Anno Saris, Yoshihiro Shimizu, Tom H. M. Ottenhoff, Alireza Mashaghi. Ebola virus-like particles reprogram cellular metabolism. Journal of Molecular Medicine. 2023
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Yoshihiro Shimizu, Naoki Tanimura, Tomoaki Matsuura. ePURE_JSBML: A Tool for Constructing a Deterministic Model of a Reconstituted Escherichia coli Protein Translation System with a User-Specified Nucleic Acid Sequence. Advanced Biology. 2023
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Keiko Kasahara, Ryohei Narumi, Satoshi Nagayama, Keiko Masuda, Tsuyoshi Esaki, Kazutaka Obama, Takeshi Tomonaga, Yoshiharu Sakai, Yoshihiro Shimizu, Jun Adachi. A large-scale targeted proteomics of plasma extracellular vesicles shows utility for prognosis prediction subtyping in colorectal cancer. Cancer Medicine. 2022
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Yuto Kuwasaki, Kazushi Suzuki, Gaigai Yu, Shota Yamamoto, Takahiro Otabe, Yuki Kakihara, Michiru Nishiwaki, Keita Miyake, Keiji Fushimi, Ramsey Bekdash, et al. A red light-responsive photoswitch for deep tissue optogenetics. Nature Biotechnology. 2022
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Ryota Miyachi, Yoshihiro Shimizu, Norikazu Ichihashi. Transfer RNA Synthesis-Coupled Translation and DNA Replication in a Reconstituted Transcription/Translation System. ACS Synthetic Biology. 2022
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MISC (30)：
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堂本 裕加子, 小川 真喜子, 永島 良樹, 大出 晃士, 清水 義宏, 上田 泰己, 深山 正久. 絶対定量的質量分析法を用いたアミロイドーシス30症例の検討. 日本病理学会会誌. 2019. 108. 1. 430-430
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清水義宏, 松浦友亮. タンパク質合成と数理モデル. 生物工学会誌. 2019. 97. 492-495
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清水義宏, Yasmine Abouleila, Ahmed Ali, 鬼谷薫, 渡邉朋信, Arno Germond, 本田一文. 一細胞質量分析によるメタボローム解析. 日本プロテオーム学会誌. 2019. 2. 2. 1-7
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永島良樹, 永島良樹, 小川真貴子, 大出晃士, 堂本裕加子, 清水義宏, 深山正久, 上田泰己, 上田泰己. 質量分析によるアミロイドーシス診断系の開発. 日本血管生物医学会学術集会プログラム・抄録集. 2018. 26th. 117
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Narumi Ryohei, Shimizu Yoshihiro, R. Ueda Hiroki. Protein Absolute Quantification Using Cell-Free-Synthesized Peptide. Proteome Letters. 2017. 2. 2. 75-82
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Books (9)：
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人工細胞の創製とその応用
シーエムシー出版 2017
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タンパク質結晶の最前線
シーエムシー出版 2013
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生命システム工学
化学同人 2012
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RNA実験ノート上巻
羊土社 2008
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やさしい原理からはいるタンパク質科学実験法 1 タンパク質をつくる
化学同人 2008
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Education (2)：
- 1998 - 2003 The University of Tokyo The Graduate School of Engineering
- 1994 - 1998 The University of Tokyo The Faculty of Engineering Department of Chemistry and Biotechnology
Professional career (1)：
Work history (7)：
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