Hiroshi Kikukawa

キクカワヒロシ | Hiroshi Kikukawa

Affiliation and department：
Job title： Associate professor

Research field (1)： Applied microbiology

Research keywords (10)： PHA , Polyhydroxyalkanoic acid , Biodegradable plastic , Biotransformation , Bioprocess production , Enzyme Engineering , Applied Microbiology , Functional Lipids , Screening of Microorganisms , Metabolic engineering

Research theme for competitive and other funds (8)：

2021 - 2025 機能性成分抽出飲料残渣からのカロテノイド生産
2021 - 2024 ビフィズス菌による新規希少脂肪酸の生産と生合成メカニズムの解明
2019 - 2021 Microbial production of rare fatty acid
2019 - 2021 Microbial production of rare fatty acid curing atopic dermatitis by normalizing skin bacterial flora
2018 - 2019 非天然アミノ酸の新奇合成法を指向した,ジオール化合物に作用する不斉酸化酵素の開発

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Papers (34)：

Yuka Hozumi, Shin-ichi Hachisuka, Hiroya Tomita, Hiroshi Kikukawa, Ken’ichiro Matsumoto. Engineering of the Long-Main-Chain Monomer-Incorporating Polyhydroxyalkanoate Synthase PhaC_AR for the Biosynthesis of Poly[(R)-3-hydroxybutyrate-co-6-hydroxyhexanoate]. Biomacromolecules. 2024
Kaoru M. Daicho, Yoko Hirono-Hara, Hiroshi Kikukawa, Kentaro Tamura, Kiyotaka Y. Hara. Engineering yeast with a light-driven proton pump system in the vacuolar membrane. Microbial Cell Factories. 2024. 23. 1
Junzhang Zhu, Yoshifumi Hikida, Hao-Liang Cai, Masaya Shimada, Hiroshi Kikukawa, Tomoyuki Nakagawa. Growth condition for over production of odd-chain fatty acids in the methylotrophic yeast Komagataella phaffii GS115. Biocatalysis and Agricultural Biotechnology. 2023. 54. 102942-102942
Hiroshi Kikukawa, Akinori Ando, Asuka Hannya, Mohd Fazli Farida Asras, Tomoyo Okuda, Takaiku Sakamoto, Kiyotaka Y. Hara, Eiji Sakuradani, Jun Ogawa. Mead acid production by disruption of Δ12-desaturase gene in Mortierella alpina 1S-4. Journal of Bioscience and Bioengineering. 2023
Hiroshi Kikukawa, Toshihiro Nagao, Mitsuki Ota, Shigeo Takashima, Kohji Kitaguchi, Emiko Yanase, Sadatoshi Maeda, Kiyotaka Y. Hara. Production of a selective antibacterial fatty acid against Staphylococcus aureus by Bifidobacterium strains. Microbiome Research Reports. 2023. 2. 1. 4-4

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MISC (23)：

Akinori Ando, Tomoyo Okuda, Hiroshi Kikukawa, Takaiku Sakamoto, Eiji Sakuradani, Jun Ogawa. Production of various ω3-polyunsaturated fatty acid-containing lipids by oleaginous microorganisms. 2020. 37. 10. 3-13
菊川寛史. バイオ系のキャリアデザイン就職支援OGOBインタビュー編. 生物工学. 2020. 98. 10. 556-557
Hiroshi Kikukawa, Yuya Kageyama, Yoko Hirono-Hara, Kiyotaka Y. Hara. Improvement of Astaxanthin Production in Xanthophyllomyces dendrorhous by Resource and Metabolic Engineering. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY. 2020. 97. 29-30
Hiroshi Kikukawa, Tomoyo Okuda, Akinori Ando, Eiji Sakuradani, Jun Ogawa. Various PUFA production by molecular breeding of Mortierella alpina 1S-4. 2020. 98. 9. 465-468
Akinori Ando, Tomoyo Okuda, Ayami Hatano, Hiroshi Kikukawa, Keisuke Matsuyama, Jun Ogawa. ω3-Docosapentaenoic acid (ω3-DPA) production by Labyrinthulea. 2020. 98. 9. 469-471

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Patents (3)：

外来性のオプシンおよび当該ロドプシンを発現した細胞
光学活性2,2-二置換-3-ヒドロキシプロピオン酸またはその塩の製造方法
(公開前)

Books (2)：

Technology and Application of ω-3 Fatty Acid
2021
Transformation of zygomycete Mortierella alpina using biolistic particle bombardment
Springer 2015

Lectures and oral presentations (11)：

My career academia
(The 75th Annual Meeting of the Society of Biotechnology of Japan 2023)
Production of an antibacterial fatty acid effective against atopic dermatitis by Bifidobacteria
(27th Shizuoka Forum on Health and Longevity 2022)
Improvement of astaxanthin production in Xanthophyllomyces dendrorhous by resource and metabolic engineering
(2020 AOCS Annual Meeting & Expo 2020)
Asymmetric oxidation of 1,3-propanediols to chiral hydroxyalkanoic acids
(Biotrans2019 (14th International Symposium on Biocatalysis and Biotransformations) 2019)
Metabolic engineering for rare PUFA production by an oil-producing fungus Mortierella alpina
(2018 AOCS Annual Meeting & Expo 2018)

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Education (3)：

2012 - 2015 Kyoto university Graduate School of Agriculture Department of Applied Life Science
2010 - 2012 Kyoto university Graduate School of Agriculture Department of Applied Life Science
2006 - 2010 Okayama university Faculty of Agriculture Course of Agrochemical Bioscience

Professional career (1)：

Ph.D. (Kyoto University)

Work history (5)：

2023/04 - 現在 Hokkaido University Graduate School of Engineering Associate professor
2019/04 - 2023/04 University of Shizuoka School of Food and Nutritional Sciences Assistant Professor
2016/04 - 2019/03 Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University Assistant Professor
2015/04 - 2016/03 Kyoto university, Japan Society for the Promotion of Science (JSPS) Research Fellowship for Young Scientists (PD)
2014/04 - 2015/03 Kyoto university, JSPS Research Fellowship for Young Scientists (DC2)

Committee career (6)：

2023/08 - 現在日本生物工学会若手の会若手シンポジウム実行委員
2023/05 - 現在日本生物工学会バイオミディア委員
2019/04 - 現在脂質駆動学術産業創生研究部会(日本生物工学会研究部会) 運営委員
2019/10 - 2023/10 日本醸造学会若手の会運営委員
2018/09 - 2023/03 日本生物工学会中部支部企画幹事

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Awards (4)：

2022/12 - 静岡県立大学教員評価における業績優秀者への学長表彰
2019/03 - 日本生化学会中部支部長賞
2017/09 - The Society for Biotechnology, Japan 25th paper award
2010/03 - The Chemical Society of Japan The branch chief award of Chugoku-Shikoku branch

Association Membership(s) (6)：

Japanese Society of Enzyme Engineering , JAPAN OIL CHEMISTS' SOCIETY , American Oil Chemists'Society , Fungal Molecular Biology Society of Japan , The Society for Biotechnology, Japan , JSBBA

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