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J-GLOBAL ID:201702240633208811   Reference number:17A0230366

Decreasing methotrexate dose after remission or low disease activity in case of rheumatoid arthritis patients: a clinical course observation

寛解ないし低疾患活動状態にある関節リウマチ患者におけるメソトレキサート減量の試み
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Volume: 28  Issue:Page: 251-259  Publication year: Dec. 30, 2016 
JST Material Number: L0625A  ISSN: 0914-8760  Document type: Article
Article type: 原著論文  Country of issue: Japan (JPN)  Language: JAPANESE (JA)
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Musculoskeletal diseases  ,  Clinical application of anti-inflammatory drugs  ,  Immunologic diseases,allergic diseases in general. 
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Reference (21):
  • 1) Andersen PA, West SG, O'Dell JR, et al: Weekly pulse methotrexate in rheumatoid arthritis. Clinical and immunologic effects in a randomized, double-blind study. Ann Intern Med, 103:489-496, 1985.
  • 2) Weinblatt ME: Toxicity of low dose meth-otrexate in rheumatoid arthritis. Rheumatol, 12:35-39, 1985.
  • 3) Gabriel S, Creagan E, O'Fallon WM, et al: Treatment of rheumatoid arthritis with higher dose intravenous methotrexate. Rheumatol, 17:460-465, 1990.
  • 4) Shinozawa T, Akama H, Matsushita Y, et al: [Low dose methotrexate therapy in rheumatoid arthritis]. Ryumachi [Rheumatism], 30:172-180, 1990.
  • 5) Tokuhira M, Watanabe R, Nemoto T, et al: Clinicopathological analyses in patients with other iatrogenic immunodeficiency-associated lymphoproliferative diseases and rheumatoid arthritis. Leuk Lymphoma, 53:616-623, 2012.
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