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J-GLOBAL ID：201702282239439229   Reference number：17A0088176

Correlation of HIF-1α/HIF-2α expression with FDG uptake in lung adenocarcinoma

肺腺癌におけるHIF-1α/HIF-2α発現とFDG取り込みとの相関

Author (10)： Higashi Kotaro (Department of Radiology, Asanogawa General Hospital, Kanazawa, Ishikawa, Japan) ,  Yamagishi Toshiaki (Department of Internal Medicine, Sabae Medical Center, Sabae, Japan) ,  Ueda Yoshimichi (Department of Pathology, Kanazawa Medical University, Ishikawa, Japan) ,  Ishigaki Yasuhito (Medical Research Institute, Kanazawa Medical University, Ishikawa, Japan) ,  Shimasaki Miyako (Department of Pathology, Kanazawa Medical University, Ishikawa, Japan) ,  Nakamura Yuka (Medical Research Institute, Kanazawa Medical University, Ishikawa, Japan) ,  Oguchi Manabu (Department of Radiation Therapy, Public Central Hospital of Matto Ishikawa, Ishikawa, Japan) ,  Takegami Tsutomu (Medical Research Institute, Kanazawa Medical University, Ishikawa, Japan) ,  Sagawa Motoyasu (Department of Thoracic Surgery, Kanazawa Medical University, Ishikawa, Japan) ,  Tonami Hisao (Department of Radiology, Kanazawa Medical University, Ishikawa, Japan)
Material： Annals of Nuclear Medicine  (Ann Nucl Med)
Volume： 30  Issue： 10  Page： 708-715  Publication year： Dec. 2016 
JST Material Number： X0838A  ISSN： 0914-7187  CODEN： ANMEEX  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *adenocarcinoma ,...
Semi thesaurus term： *Adenocarcinoma lung ,...

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Author keywords (5)： PET ,  18F-FDG ,  Lung adenocarcinoma ,  Hypoxia-inducible factor ,  Recurrence

JST classification (3)： Diagnosis of tumors(=neoplasms)  (GE03020J) ,  Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Clinical application of diagnostic drugs  (GW20020A)

Substance index (1)： 18F-FDG

Reference (29)：

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• Jiang BH, Semenza GL, Bauer C, Marti HH. Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. Am J Physiol. 1996;271:1172-80.
• Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med. 2003;9:677-84.
• Schofield CJ, Ratcliffe PJ. Oxygen sensing by HIF hydroxylases. Nat Rev Mol Cell Biol. 2004;5:343-54.

Terms in the title (7)： 肺腺癌 ,  HIF-1α ,  HIF-2α ,  発現 ,  FDG ,  取り込み ,  相関