Art

J-GLOBAL ID：201702290959758898   Reference number：17A0025027

Analysis of the Efficacy and Safety of Switching from Twice-daily Premixed Insulin to Basal Plus Two Times Bolus Insulin Therapy

基礎インスリン1回および追加インスリン2回併用療法の臨床的有効性と安全性についての検討

Author (5)： KIMURA RYOSUKE (名古屋市西部医療セ 内分泌・糖尿病内科) ,  OKAMOTO ASAMI (名古屋市西部医療セ 内分泌・糖尿病内科) ,  TAKEDA KATSUSHI (名古屋市西部医療セ 内分泌・糖尿病内科) ,  WATANABE KUMIKO (名古屋市西部医療セ 内分泌・糖尿病内科) ,  YASUI SACHIE (名古屋市西部医療セ 内分泌・糖尿病内科)
Material： 新薬と臨床  (Journal of New Remedies & Clinics)
Volume： 66  Issue： 1  Page： 11-21  Publication year： Jan. 10, 2017 
JST Material Number： G0596A  ISSN： 0559-8672  CODEN： SHRIA  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *insulin ,...
Semi thesaurus term： *basal insulin ,...

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JST classification (2)： Clinical application of drugs acting on carbohydrate metabolism  (GW13030B) ,  Treatment for metabolic diseases,nutritional diseases.  (GD05030F)

Reference (22)：

• Holman RR, Thorne KI, Farmer AJ, et al. ; 4-T Study Group. Addition of biphasic, prandial, or basal insulin to oral therapy in type 2 diabetes. N Engl J Med. 2007 ; 357 ; 1716- 1730.
• Holman RR, Farmer AJ, Davies MJ, et al. ; 4-T Study Group. Three-year efficacy of complex insulin regimens in type 2 diabetes. N Engl J Med. 2009 ; 361 ; 1736-1747.
• Davidson MB, Raskin P, Tanenberg RJ, et al. A stepwise approach to insulin therapy in patients with type 2 diabetes mellitus and basal insulin treatment failure. Endocr Pract. 2011 ; 17 : 395-403.
• Owens DR, Luzio SD, Sert-Langeron C, Riddle MC. Effects of initiation and titration of a single pre-prandial dose of insulin glulisine while continuing titrated insulin glargine in type 2 diabetes : a 6-month ‘proof-of-concept' study. Diabetes Obes Metab. 2011 ; 13 ; 1020-1027.
• Lankisch MR, Ferlinz KC, Leahy JL, Scherbaum WA, Orals Plus Apidra and LANTUS (OPAL) study group. Introducing a simplified approach to insulin therapy in type 2 diabetes : a comparison of two single-dose regimens of insulin glulisine plus insulin glargine and oral antidiabetic drugs. Diabetes Obes Metab. 2008 ; 10 : 1178-1185.

Terms in the title (5)： 基礎インスリン ,  インスリン ,  併用療法 ,  臨床的有効性 ,  安全性