Rchr
J-GLOBAL ID：201801004598851984
Update date: Mar. 20, 2024
Ichimura Koichi
イチムラ コウイチ | Ichimura Koichi
Affiliation and department：
Job title：
Specially Appointed Professor
Other affiliations (1)：
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National Cancer Center
Research Institute
Homepage URL (1)：
https://www.ncc.go.jp/jp/ri/division/brain_tumor_translational_research/index.html
Research field (2)：
Pathobiochemistry
, Neurosurgery
Research keywords (5)：
Glioma
, Pediatric brain tumor
, Cancer Genomics
, Pediatric cancer
, Brain tumor
Research theme for competitive and other funds (16)：
- 2022 - 2025 ロングリード技術を用いた統合ゲノム解析による中枢神経系胚細胞腫の病態解明
- 2021 - 2024 脳悪性リンパ腫における髄液中DNAの特異的遺伝子変異検出による診断の前方視的検討
- 2021 - 2024 Revealing specific local invasion mechanism in CNS using small cell lung cancer metastasis cell lines
- 2020 - 2024 中枢神経系悪性リンパ腫の腫瘍内多様性と微小環境解析による病態発生の解明と治療開発
- 2020 - 2023 網羅的メチル化解析で同定された頭蓋内高悪性度胚細胞腫治療標的候補分子群の機能解析
- 2020 - 2023 中枢神経系悪性リンパ腫臨床試験における網羅的遺伝子解析による予後及び予測因子解析
- 2019 - 2023 悪性脳腫瘍におけるポリグルタミル化制御による新規治療法の開発
- 2019 - 2022 A comprehensive genomic analysis of central nervous system germ cell tumors and generation of their cellular model
- 2018 - 2021 Comparative genetic analysis of central nervous system lymphomas between sites in the central nervous system or extracranial organs
- 2017 - 2021 Development of non-invasive novel diagnostic methods for primary central nervous system lymphoma using liquid biopsy for nucleic acids derived from cerebrospinal fluid
- 2016 - 2021 Detection and clinical application of pilocytic astrocytoma minimal residual disease
- 2016 - 2020 Functional analysis of specific genetic alterations in primary central nervous system lymphomas and development of novel molecular targeted therapies
- 2016 - 2019 Investigation of TERT expression and development of a novel targeted therapy in ependymomas
- 2016 - 2018 enome-wide DNA methylation profiling identifies primary central nervous system lymphomas as a distinct entity from systemic diffuse large B-cell lymphomas
- 2013 - 2016 Identification of novel prognostic markers for glioblastomas by means of next-generation sequencing-ased targeted resequencing
- 1991 - 1991 聴神経鞘腫および両側性神経線維腫症の遺伝子のクローニングに関する研究
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Papers (329)：
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Sina Neyazi, Erika Yamazawa, Karoline Hack, Shota Tanaka, Genta Nagae, Catena Kresbach, Takayoshi Umeda, Alicia Eckhardt, Kenji Tatsuno, Lara Pohl, et al. Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation. Acta Neuropathologica. 2024. 147. 1
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Yukina Shirai, Toshihide Ueno, Shinya Kojima, Hiroshi Ikeuchi, Rina Kitada, Takafumi Koyama, Fumiyuki Takahashi, Kazuhisa Takahashi, Koichi Ichimura, Akihiko Yoshida, et al. The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma. Journal of neuro-oncology. 2024
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Takashi Fujii, Yoshiko Nakano, Daichi Hagita, Nobuyuki Onishi, Arumu Endo, Masaya Nakagawa, Toru Yoshiura, Yohei Otsuka, Satoru Takeuchi, Mario Suzuki, et al. KLC1-ROS1 Fusion Exerts Oncogenic Properties of Glioma Cells via Specific Activation of JAK-STAT Pathway. Cancers. 2023. 16. 1
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Seiji Yamada, Motoki Tanikawa, Yuko Matsushita, Ryota Fujinami, Hiroshi Yamada, Kaishi Sakomi, Tomohiro Sakata, Hidehito Inagaki, Hideaki Yokoo, Koichi Ichimura, et al. SEGA-like circumscribed astrocytoma in a non-NF1 patient, harboring molecular profile of GBM. A case report. Neuropathology : official journal of the Japanese Society of Neuropathology. 2023
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Toru Odate, Kaishi Satomi, Takashi Kubo, Yuko Matsushita, Toshihide Ueno, Akira Kurose, Kohei Shomori, Tokiko Nakai, Reiko Watanabe, Keiko Segawa, et al. Inflammatory Rhabdomyoblastic Tumor: Clinicopathologic and Molecular Analysis of 13 Cases. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2023. 37. 1. 100359-100359
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MISC (149)：
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田尾 佳代子, 加藤 元博, 義岡 孝子, 加藤 実穂, 久保 崇, 高阪 真路, 谷田部 恭, 瀧本 哲也, 市村 幸一, 望月 慎史, et al. 小児・AYAがんにおけるゲノム医療の現状と課題 全国小児がんゲノムプロファイリングプロジェクト JCCG-TOP2. 日本癌治療学会学術集会抄録集. 2022. 60回. OWS23-3
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高橋 雅道, 川嶋 聡, 口羽 文, 佐立 崚, 米盛 勧, 永根 基雄, 荒川 芳輝, 武笠 晃丈, 田中 將太, 西川 亮, et al. 再発膠芽腫に対するエリブリンの第2相多施設単群医師主導治験. 日本癌治療学会学術集会抄録集. 2022. 60回. EN6-3
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田尾 佳代子, 加藤 元博, 義岡 孝子, 加藤 実穂, 久保 崇, 高阪 真路, 谷田部 恭, 瀧本 哲也, 市村 幸一, 望月 慎史, et al. 全国小児がんゲノムプロファイリングプロジェクト JCCG-TOP2(The Nationwide Pediatric Cancer Genome Profiling Project: JCCG-TOP2). 日本癌学会総会記事. 2022. 81回. P-1071
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Issay Kitabayashi, Yukiko Aikawa, Kazutsune Yamagata, Takuo Katsumoto, Yutaka Shima, Akihiko Yokoyama, Yukino Machida, Haruka Shinohara, Yoko Ogawara, Shuhei Fujita, et al. Targeting driver mutations and critical factors in hematological and solid cancers. CANCER SCIENCE. 2022. 113. 1256-1256
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佐々木重嘉, 久米賢, 立石健祐, 中村大志, 井林賢志, 山岸夢希, 齊藤邦昭, 小林啓一, 松下裕子, 日比谷優子, et al. Paired mutational analysis in secondary nervous system lymphoma and PCNSL systemic relapse reveals driver mutation candidates in the central nervous system. 日本脳腫瘍学会学術集会プログラム・抄録集. 2022. 40th
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Education (3)：
- 1994 - 1996 Karolinska Institute Tumor Pathology
- 1992 - 1994 Gothenburg University Department of Pathology
- 1979 - 1985 Tokyo Medical and Dental University School of Medicine
Professional career (1)：
- M.D., Ph.D. (Karolinska Institute, Stockholm)
Work history (12)：
- 2021/04 - 現在 Juntendo University Department of Brain Disease Translational Research, Faculty of Medicine Specially Appointed Professor
- 2011/10 - 2021/03 National Cancer Center Japan Brain Tumor Translational Research Chief
- 1998/07 - 2011/06 University of Cambridge Department of Pathology Senior Research Associate
- 1996/07 - 1998/06 Ludwig Institute for Cancer Research Stockholm branch Postdoctoral fellow
- 1994/05 - 1996/06 Karolinska Institute Tumor Pathology Doctoral student
- 1989/10 - 1994/09 Tokyo Medical and Dental University Department of Neurosurgery Research Associate
- 1991/10 - 1994/04 University of Gothenburg Department of Pathology Doctoral student
- 1988/10 - 1989/09 Tokyo Medical and Dental University Department of Neurosurgery
- 1987/07 - 1988/09 富士吉田市立病院 脳神経外科 医員
- 1986/07 - 1987/06 Tokyo Medical and Dental University Department of Neurosurgery
- 1985/11 - 1986/06 土浦協同病院 脳神経外科 医員
- 1985/06 - 1985/10 Tokyo Medical and Dental University Department of Neurosurgery
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Association Membership(s) (7)：
AMERICAN ASSOCIATION FOR CANCER RESEARCH
, THE SOCIETY OF NEURO-ONCOLOGY
, THE JAPAN SOCIETY OF MOLECULAR NEUROSURGERY
, THE JAPAN NEUROSURGICAL SOCIETY
, THE JAPANESE CANCER ASSOCIATION
, THE JAPAN SOCIETY OF BRAIN TUMOR PATHOLOGY
, THE JAPAN SOCIETY FOR NEURO-ONCOLOGY
