Irie Raku

イリエラク | Irie Raku

Affiliation and department：
Job title： Assistant Professor

Research field (2)： Marine/Aquatic life sciences , Molecular biochemistry

Research keywords (1)： Natural Products Chemistry

Research theme for competitive and other funds (6)：

2023 - 2026 化学合成で紐解くポリアミン-ペプチド複合型海産毒の修飾様式と活性中核構造
2022 - 2025 細胞膜で多彩に機能する有機化合物の合成化学的開発
2021 - 2024 Development of an identification method of functionality from alpha-pinene oxidation using an accurate corona discharge ionization collision-induced dissociation mass spectrometry
2019 - 2023 化学反応を駆使した多官能基性天然物の構造と作用機序研究
2019 - 2020 創薬シーズとして有望な天然有機化合物の新規構造決定法の開発

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Papers (22)：

Kenji Morokuma, Hiromi Watari, Maika Mori, Ryuichi Sakai, Raku Irie, Masato Oikawa. Total synthesis of lycoperdic acid and stereoisomers (part 2): Completion of the synthesis and biological evaluation. Tetrahedron. 2023. 133623
Kenji Morokuma, Kento Tanaka, Raku Irie, Masato Oikawa. Total synthesis of lycoperdic acid and stereoisomers (part 1): Double asymmetric hydrogenation of a racemic enamide. Tetrahedron. 2023. 133622
Masayoshi Miyahara, Ryoya Wakabayashi, Raku Irie, Masato Oikawa. Synthesis of a fully protected long-chain polyamine subunit of aculeine B using the photoremovable NPEC group. Organic & Biomolecular Chemistry. 2023. 21. 17. 3636-3643
Kazunori Otsuka, Masayoshi Miyahara, Sara Takaki, Ryoya Wakabayashi, Kei Miyako, Raku Irie, Satoshi Takamizawa, Ryuichi Sakai, Masato Oikawa. Synthetic Studies on the Initially Proposed Structure of Protoaculeine B: Discovery of Neuronally Active Heterotricyclic Amino Acids. European Journal of Organic Chemistry. 2022. 2022. 36
Shuntaro Tsukamoto, Oriel Hlokoane, Kei Miyako, Raku Irie, Ryuichi Sakai, Masato Oikawa. Oxa-Michael-based divergent synthesis of artificial glutamate analogs. RSC Advances. 2022. 12. 34. 22175-22179

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MISC (2)：

入江樂, 及川雅人. Cys間のジスルフィド結合-ペプチドの古くて新しい環化戦略. 化学. 2024. 79. 2. 68-69
Olefin Metathesis. Journal of Synthetic Organic Chemistry, Japan. 2020. 78. 4. 365-365

Lectures and oral presentations (46)：

Aculeine類のペプチド部分AcuPepの構造解析
(日本化学会第104春季年会 2024)
蛍光標識化が可能なポリアミン類縁体の効率合成
(日本化学会第104春季年会 2024)
Poecillastrin類の構造解析に向けた分解反応の試み
(日本化学会第104春季年会 2024)
Multicomponent Synthesis of 4-Iminoimidazolidines and their Bioactivities
(日本化学会第104春季年会 2024)
Lewis Acid-Catalyzed Three-Component Reaction of isocyanides, amines, and aldehydes for the Synthesis of Iminoimidazolidines
(2023)

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Education (3)：

- 2018 The University of Tokyo (Prof. Shigeki Matsunaga) Graduate School of Agricultural and Life Sciences Department of Aquatic Bioscience
- 2015 The University of Tokyo (Prof. Kazuo Tachibana) Graduate School of Science Department of Chemistry
- 2013 The University of Tokyo (Prof. Kazuo Tachibana) School of Science Department of Chemistry

Professional career (2)：

Work history (3)：

2018/09 - 現在 Yokohama City University Institute of Natural Science, Association of International Arts and Sciences Assistant Professor
2018/04 - 2018/08 Japan Society for the Promotion of Science Research Fellowship for Young Scientists (PD)
2017/04 - 2018/03 Japan Society for the Promotion of Science Research Fellowship for Young Scientists (DC2)

Association Membership(s) (3)：

THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN , THE JAPANESE SOCIETY OF FISHERIES SCIENCE , THE CHEMICAL SOCIETY OF JAPAN

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