Rchr
J-GLOBAL ID：201801006157105422   Update date: Apr. 03, 2024

KAWAGISHI Hiroyuki

KAWAGISHI Hiroyuki
Affiliation and department：
National Institute of Health Sciences

About National Institute of Health Sciences


Research keywords  (4)： 安全性薬理 ,  Cellular Senescence ,  Cardiomyocytes ,  Pediatric heart failure
Papers (15)：
  • Hiroyuki Kawagishi, Tsutomu Nakada, Takuro Numaga-Tomita, Maite Larrañaga, Ang Guo, Long-Sheng Song, Mitsuhiko Yamada. Cytokine receptor gp130 promotes postnatal proliferation of cardiomyocytes required for the normal functional development of the heart. American Journal of Physiology-Heart and Circulatory Physiology. 2022
  • Nanqi Cui, Takayuki Sakurai, Akiko Kamiyoshi, Yuka Ichikawa-Shindo, Hisaka Kawate, Megumu Tanaka, Masaaki Tanaka, Yangxuan Wei, Shinji Kakihara, Yunlu Zhao, et al. Adrenomedullin-RAMP2 and -RAMP3 Systems Regulate Cardiac Homeostasis during Cardiovascular Stress. Endocrinology. 2021. 162. 3
  • Ryan Houston, Shiori Sekine, Michael J Calderon, Fayaz Seifuddin, Guanghui Wang, Hiroyuki Kawagishi, Daniela A Malide, Yuesheng Li, Marjan Gucek, Mehdi Pirooznia, et al. Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses. PLoS biology. 2020. 18. 11. e3000981
  • Toshihide Kashihara, Hiroyuki Kawagishi, Tsutomu Nakada, Takuro Numaga-Tomita, Shin Kadota, Elena E Wolf, Cheng-Kun Du, Yuji Shiba, Sachio Morimoto, Mitsuhiko Yamada. β-Arrestin-Biased AT1 Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate. JACC. Basic to translational science. 2020. 5. 11. 1057-1069
  • Nomura M, Liu J, Yu ZX, Yamazaki T, Yan Y, Kawagishi H, Rovira II, Liu C, Wolfgang MJ, Mukouyama YS, et al. Macrophage fatty acid oxidation inhibits atherosclerosis progression. Journal of molecular and cellular cardiology. 2019
ｍore...
MISC (6)：
  • 川岸裕幸, 山田充彦. βアレスチンバイアス性アンジオテンシンII 1型受容体アゴニストによる新たな小児心不全治療戦略の創生. 血管. 2022
  • 川岸裕幸, 山田充彦. 新生児マウス心臓の機能的発達におけるサイトカイン受容体gp130の役割. 信州医学雑誌. 2022
  • 川岸裕幸, 山田充彦. βアレスチンバイアスAT1受容体アゴニストは新しい乳幼児心不全治療薬の有力候補である。. 医学のあゆみ. 2021. 276. 12. 1137-1138
  • Hiroyuki Kawagishi, Mitsuhiko Yamada. A novel way of modification of AT1 angiotensin receptors to alleviate neonatal and infantile heart failure. Folia Pharmacologica Japonica. 2021. 156. 6. 351-354
  • Hiroyuki Kawagishi, Toren Finkel. Unraveling the Truth About Antioxidants: ROS and disease: finding the right balance. Nature Medicine. 2014. 20. 7. 711-713
ｍore...
Books (1)：
  • 老年医学(上巻)-基礎・臨床研究の最新動向-
    日本臨牀 2018
Lectures and oral presentations  (46)：
  • アンジオテンシン受容体を標的とした新生児・乳児心不全治療薬の開発
    (日本薬学会第144年会 2024)
  • Mechanisms underlying the efficacy and safety of β-arrestin-biased AT1 agonists as therapeutics for neonatal and infantile heart failure
    (2023)
  • In-vitro and pharmacovigilance assessments of cardiotoxicity of VEGFR-tyrosine kinase inhibitors
    (2023)
  • Assessment of Cardiac Contractility Using Aligned Human iPS Cell-Derived Cardiomyocytes
    (2023 Safety Pharmacology Society (SPS) ANNUAL MEETING 2023)
  • 液性因子による新生児期特有の生理作用と その制御機構の探索
    (第46回日本基礎老化学会大会 2023)
ｍore...
Professional career (1)：
  • Ph.D. (Nagoya University, School of Medicine)
Awards (5)：
  • 2022/12 - 第96回日本薬理学会年会 Young Investigator Award
  • 2022/06 - 第146回日本薬理学会関東部会 優秀発表賞
  • 2021/07 - 第50回日本心脈管作動物質学会 研究奨励賞 最優秀賞
  • 2020/11 - 第30回日本循環薬理学会 Young Investigator Award
  • 2008 - National Center for Geriatrics and Gerontology Young Investigator Award
Association Membership(s) (11)：
日本毒性学会 ,  日本薬学会 ,  SPS ,  日本安全性薬理学会 ,  日本生理学会 ,  日本基礎老化学会 ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  日本心脈管作動物質学会 ,  Japanese Association of Cardiovascular Pharmacology ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  International Society for Heart Research
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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