Fukushima Yuta

フクシマユウタ | Fukushima Yuta

Affiliation and department：
Job title： Assistant Professor

Research field (5)： Biomaterials , Biomedical engineering , Nanobioscience , Neuroscience - general , Neurosurgery

Research keywords (5)：アストロサイト , DDS , mRNA医薬 , 虚血性神経細胞死 , 神経再生

Research theme for competitive and other funds (6)：

2021 - 2024 mRNA医薬による反応性アストロサイトの機能変換を標的とする脳梗塞後遺症再生治療
2020 - 2021 Neurological regeneration after cerebral ischemia with mRNA medicine
2019 - 2021 Functional regeneration after ischemic stroke with mRNA therapy: Enhancement of cortical plasticity
2016 - 2018 ナノミセルを用いたmRNA導入による神経細胞死に対する神経保護
mRNA医薬による反応性アストロサイトの機能変換を標的とする脳梗塞後遺症再生治療

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Papers (21)：

Fukushima Y, Uchida S, Imai H, Nakatomi H, Kataoka K, Saito N, Itaka K. Treatment of ischemic neuronal death by introducing brain-derived neurotrophic factor mRNA using polyplex nanomicelle. Biomaterials. 2021. 270. 120681-120681
蛯原郁弥, 長田和也, 福島雄大, 松本征仁, 位高啓史. 骨格筋を標的とするmRNA医薬の開発と末梢神経障害治療への応用. 日本バイオマテリアル学会大会予稿集. 2019. 41回. 512-512
蛯原郁弥, 長田和也, 福島雄大, 松本征仁, 位高啓史. mRNA医薬の骨格筋への投与による末梢神経障害の早期機能回復. 日本DDS学会学術集会プログラム予稿集. 2019. 35回. 182-182
福島雄大, 内田智士, 片岡一則, 位高啓史. mRNA医薬の脳神経保護薬への展開 BDNF mRNAのナノミセルによる脳室内投与. 日本DDS学会学術集会プログラム予稿集. 2019. 35回. 154-154
Crowley ST, Fukushima Y, Uchida S, Kataoka K, Itaka K. Enhancement of Motor Function Recovery after Spinal Cord Injury in Mice by Delivery of Brain-Derived Neurotrophic Factor mRNA. Molecular therapy. Nucleic acids. 2019. 17. 465-476

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MISC (2)：

Books (1)：

Lectures and oral presentations (24)：

mRNA therapeutics for the central nervous systems: Treatment of ischemic stroke and spinal cord injury
(2021)
mRNA医薬による虚血性中枢神経疾患に対する新たな治療法開発
(創薬薬理フォーラム第69回談話会 2021)
mRNA医薬の新しい展開:脳虚血性疾患に対する新たな治療法開発
(東京医科歯科大学プレスリリース記者会見 2021)
Intraventricular BDNF mRNA administration prevents ischemic neuronal death with the uptake predominantly by astrocytes
(8th International mRNA Health Conference 2020)
BDNF-expressing mRNA medicine for central nervous system disorders
(6th COINS Symposium 2019)

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Education (3)：

2014 - 2018 The University of Tokyo Graduate School, Division of Medical Sciences
2003 - 2007 The University of Tokyo Faculty of Medicine
2001 - 2003 The University of Tokyo Faculty of Liberal Arts

Professional career (1)：

Work history (13)：

2019/05/01 - 現在 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering Biofunctional Restoration Material Biofunctions Assistant Professor
2018/12/01 - 現在公益財団法人川崎市産業振興財団ナノ医療イノベーションセンター (iCONM) 客員研究員
2018/11/16 - 現在東京大学大学院医学系研究科脳神経医学登録研究員
2018/10/01 - 2019/04/30 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering Biofunctional Restoration Material Biofunctions Project Assistant Professor
2018/10/01 - 2019/04/30 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering Biofunctional Restoration Material Biofunctions Assistant Professor

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Awards (4)：

2021/06 - Nucleic Acids Therapeutics Society of Japan Encouragement prize (DDS) mRNA therapeutics for the central nervous systems: Treatment of ischemic stroke and spinal cord injury
2020/01 - 18th IBB BioFuture Research Encouragement Prize
2019/12 - 6th COINS Symposium Best Poster Award BDNF-expressing mRNA medicine for central nervous system disorders.
2017/04 - International Society of Cerebral Blood Flow and Metabolism Early Career Investigator Travel Bursary for 28th Symposium on Cerebral Blood Flow, Metabolism and Function Transient BDNF introduction therapy against delayed neuronal death in hippocampal CA1 neurons using biocompatible nanomicellar mRNA carrier.

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