Wada Shun'ichi

Affiliation and department：

Research field (2)： Environmental and pharmaceutical development resources , Pharmaceuticals - chemistry and drug development

Research keywords (3)： DDS , 核酸医薬 , 膜透過性ペプチド

Research theme for competitive and other funds (8)：

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Papers (81)：

Junsuke Hayashi, Yosuke Ochi, Kota Senpuku, Shun-Ichi Wada, Fumito Wada, Mariko Harada-Shiba, Hidehito Urata. Rational design of prodrug-type apoB-targeted siRNA for nuclease resistance improvement without compromising gene silencing potency. Bioorganic & medicinal chemistry. 2024. 104. 117693-117693
Norihito Sugimoto, Junsuke Hayashi, Ryohei Funaki, Shun-Ichi Wada, Fumito Wada, Mariko Harada-Shiba, Hidehito Urata. Prodrug-Type Phosphotriester Oligonucleotides with Linear Disulfide Promoieties Responsive to Reducing Environment. Chembiochem : a European journal of chemical biology. 2023. e202300526
Shun-Ichi Wada, Akira Shibaike, Junsuke Hayashi, Hidehito Urata. Influence of Aib-Containing Amphipathic Helical Chain Length in MAP(Aib)-cRGD as Carrier for siRNA Delivery. Chemistry & biodiversity. 2022. 19. 2. e202100728
Tatsuya Funai, Chizuko Tagawa, Osamu Nakagawa, Shun-ichi Wada, Akira Ono, Hidehito Urata. Enzymatic formation of consecutive thymine-HgII-thymine base pairs by DNA polymerases. Chemical Communications. 2020. 56. 80. 12025-12028
Funai T, Aotani M, Kiriu R, Nakamura J, Miyazaki Y, Nakagawa O, Wada SI, Torigoe H, Ono A, Urata H. Silver(I) ion-mediated cytosine-containing base pairs: Metal ion specificity for duplex stabilization and susceptibility toward DNA polymerases. Chembiochem : a European journal of chemical biology. 2020. 21. 4. 517-522

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MISC (5)：

Books (4)：

Lectures and oral presentations (37)：

EFFECT OF LYSINE REPLACEMENT WITH ARGININE IN AMPHIPATHIC HELICAL PEPTIDE ON siRNA DELIVERY INTO CELLS
(2023)
ApoB標的アンチセンス核酸gap領域へのリン酸トリエステル修飾の導入と活性への影響
(日本核酸医薬学会第8回年会 2023)
ヌクレアーゼ抵抗性改善を目指した部分修飾ApoB標的プロドラッグ型siRNAの設計
(日本薬学会第143年会 2023)
MAP(Aib)のArg置換によるsiRNA細胞内デリバリーへの影響
(日本薬学会第143年会 2023)
細胞膜透過性ペプチドー5-アミノレブリン酸複合体の合成
(第72回日本薬学会関西支部総会・大会 2022)

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Professional career (1)：

Work history (2)：

Association Membership(s) (3)：

The Japanese Peptide Society , THE PHARMACEUTICAL SOCIETY OF JAPAN , 日本薬学会医薬化学部会

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