Rchr
J-GLOBAL ID:201801012343093434   Update date: Feb. 01, 2024

Yamanishi Kyosuke

ヤマニシ キョウスケ | Yamanishi Kyosuke
Affiliation and department:
Research field  (1): Psychiatry
Research keywords  (3): 精神免疫 ,  depression ,  InterLeukin 18
Research theme for competitive and other funds  (8):
  • 2023 - 2026 インフラマソームを中心とした末梢炎症がうつ病を引き起こす機序解明と治療戦略の模索
  • 2022 - 2023 The investigation of the neuroinflammatory regulation mechanism focusing on inflammasome
  • 2020 - 2023 The investigation between psychiatric disorders and neuroinflammation focused by interleukin 18
  • 2021 - 2022 Establishing new mechanism of interleukin 18 on central nerve system and application for depression
  • 2019 - 2022 インターロイキン18を中心とした脳内炎症と精神疾患への作用解明
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Papers (39):
  • Kyosuke Yamanishi, Masaki Hata, Naomi Gamachi, Yuko Watanabe, Chiaki Yamanishi, Haruki Okamura, Hisato Matsunaga. Molecular Mechanisms of IL18 in Disease. International journal of molecular sciences. 2023. 24. 24
  • Masahiro Miyauchi, Naomi Matsuura, Keiichiro Mukai, Takuya Hashimoto, Shun Ogino, Kyosuke Yamanishi, Hisashi Yamada, Kazuhisa Hayashida, Hisato Matsunaga. A prospective investigation of impacts of comorbid attention deficit hyperactivity disorder (ADHD) on clinical features and long-term treatment response in adult patients with obsessive-compulsive disorder (OCD). Comprehensive psychiatry. 2023. 125. 152401-152401
  • Pedro S Marra, Yoshitaka Nishizawa, Takehiko Yamanashi, Eleanor J Sullivan, Katie R Comp, Kaitlyn J Crutchley, Nadia E Wahba, Kazuki Shibata, Tsuyoshi Nishiguchi, Kyosuke Yamanishi, et al. NSAIDs use history: impact on the genome-wide DNA methylation profile and possible mechanisms of action. Clinical and experimental medicine. 2023
  • Kyosuke Yamanishi, Nobutaka Doe, Keiichiro Mukai, Takuya Hashimoto, Naomi Gamachi, Masaki Hata, Yuko Watanabe, Chiaki Yamanishi, Hideshi Yagi, Haruki Okamura, et al. Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice. Translational psychiatry. 2022. 12. 1. 404-404
  • Iveta Nedeva, Antoaneta Gateva, Yavor Assyov, Vera Karamfilova, Julieta Hristova, Kyosuke Yamanishi, Zdravko Kamenov, Haruki Okamura. IL-18 Serum Levels in Patients with Obesity, Prediabetes and Newly Diagnosed Type 2 Diabetes. Iranian journal of immunology : IJI. 2022. 19. 2. 199-206
more...
MISC (56):
  • 山西 恭輔. インフラマソームを中心とした末梢炎症がうつ病を引き起こす機序解明と新規治療戦略の模索. 先進医薬研究振興財団研究成果報告集. 2023. 2022年度. 72-74
  • 李 文, 高井 真司, 金 徳男, 山西 恭輔, 山西 博道, 岡村 春樹. IL-18の抗腫瘍作用 effector CD8 T cellの代謝/増殖に及ぼす影響(IL-18 enhances anti-tumor effect of memory CD8+ T cells by augmenting metabolic activity and function). 日本癌学会総会記事. 2022. 81回. P-1155
  • 山西 恭輔, 土江 伸誉, 向井 馨一郎, 橋本 卓也, 蒲池 直美, 秦 正樹, 渡辺 優子, 山西 千晶, 岡村 春樹, 松永 寿人. インターロイキン18の急性ストレス下での脳内炎症と精神症状への影響について. 精神神経学雑誌. 2022. 124. 4付録. S-642
  • 山西 恭輔, 宮内 雅弘, 向井 馨一郎, 橋本 卓也, 宇和 典子, 大谷 佐知[桑原], 前田 誠司, 蒲池 直美, 李 文, 秦 正樹, et al. インターロイキン18(IL-18)の欠損状態がうつ病様変化を呈する前頭前野を中心とした分子メカニズムの探索. 精神神経学雑誌. 2021. 2021特別号. S561-S561
  • 松永 寿人, 向井 馨一郎, 山西 恭輔. 【強迫についてあらためて考える】不安の病気としての強迫症 強迫神経症から強迫スペクトラムに至る過程を含めて. 精神医学. 2021. 63. 6. 897-904
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Patents (1):
Lectures and oral presentations  (6):
  • Epigenetic analysis of depression-like behavior in interleukin-18-deficient mice
    (24th World Congress on Advances in Oncology and 24 th International Symposium on Molecular Medicine 2019)
  • Histone acetylation and neurogenesis are associated with hippocampal abnormalities in interleukin-18-deficient mice
    (23rd World Congress on Advances in Oncology and 22nd International Symposium on Molecular Medicine 2018)
  • An investigation regarding the causal effect of interleukin-18-deficient condition on hippocampal abnormalities and depression-like behavioral changes
    (WFSBP 2018 KOBE 2018)
  • Interleukin-18-deficient mice develop dysfunction of hippocampus resulting in depression-like behavior
    (WPA XVII World Congress of Psychiatry 2017)
  • Interleukin-18-deficient mice develop dysfunction of hippocampus resulting in depression-like behavior
    (21th World Congress on Advances in Oncology and 19th International Symposium on Molecular Medicine 2016)
more...
Professional career (1):
  • 博士(医学) (兵庫医科大学院)
Awards (3):
  • 2022/07 - JSNP Excellent Presentation Award for CINP 2022
  • 2018/06 - 114th Annual Meeting of the Japanese Society of Psychiatry and Neurology. Best Presentation Award
  • 2017/06 - 113th Annual Meeting of the Japanese Society of Psychiatry and Neurology Best Presentation Award
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