Rchr
J-GLOBAL ID:201801013024712730   Update date: Apr. 22, 2024

Kurosaka Hiroshi

Kurosaka Hiroshi
Affiliation and department:
Job title: Associate Professor
Research field  (2): Oral medicine ,  Developmental dentistry
Research keywords  (8): Developmental Biology ,  Rare Disease ,  Orthodontics ,  Craniofacial development ,  Cranial neural crest ,  Genetics ,  Cleft lip and/or Palate ,  Craniofacial defect
Research theme for competitive and other funds  (29):
  • 2023 - 2026 Development of a treatment method for maxillofacial dysplasia caused by parathyroid hormone (PTH) signaling disorder
  • 2022 - 2025 非症候性原発性萌出不全における遺伝的要因の探索と新規治療法の確立
  • 2021 - 2025 A novel strategy for molecular diagnosis and prophylactic approach to non-syndromic cleft palate
  • 2022 - 2024 多因子トランスオミックス解析で挑む口唇口蓋裂研究の新戦略
  • 2021 - 2024 レチノイン酸シグナルと相互作用を持つ顎顔面形成に関わる新規病的因子の解析
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Papers (110):
  • Namiki Nagata, Hiroshi Kurosaka, Kotaro Higashi, Masaya Yamaguchi, Sayuri Yamamoto, Toshihiro Inubushi, Miho Nagata, Yasuki Ishihara, Ayumi Yonei, Yohei Miyashita, et al. Characteristic craniofacial defects with novel truncated mutation of USP9X. Human Genome Variation. 2024. In press
  • Sayuri Yamamoto, Hiroshi Kurosaka, Kiyomi Mihara, Motohiro Onoda, Seiji Haraguchi, Takashi Yamashiro. Long-term follow-up of a patient diagnosed with Crouzon syndrome who underwent Le Fort I and III distraction osteogenesis using a rigid external distractor system. Angle Orthodontist. 2023. 93. 6. 736-746
  • Toshihiro Inubushi, Nag Priyanka, Masakatsu Watanabe, Yusuke Takahashi, Shinnosuke Kusano, Hiroshi Kurosaka, Silvana Papagerakis, Petros Papagerakis, Mikako Hayashi, Takashi Yamashiro. On-demand chlorine dioxide solution enhances odontoblast differentiation through desulfation of cell surface heparan sulfate proteoglycan and subsequent activation of canonical Wnt signaling. Frontiers in Cell and Developmental Biology. 2023. 11. 1271455-1271455
  • Naoki Yoshida, Toshihiro Inubushi, Takumi Hirose, Gozo Aoyama, Hiroshi Kurosaka, Takashi Yamashiro. The roles of JAK2/STAT3 signaling in fusion of the secondary palate. Disease models & mechanisms. 2023. 16. 10
  • P. Nag, T. Inubushi, J.I. Sasaki, T. Murotani, S. Kusano, Y. Nakanishi, Y. Shiraishi, H. Kurosaka, S. Imazato, Y. Yamaguchi, et al. Tmem2 Deficiency Leads to Enamel Hypoplasia and Soft Enamel in Mouse. Journal of Dental Research. 2023. 102. 10. 1162-1171
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MISC (92):
Patents (1):
Books (1):
  • Orthodontics for Dental Students
    Ishiyaku Publishers, Inc 2019
Lectures and oral presentations  (40):
  • Comprehensive treatment of malocclusion with orofacial cleft
    (Lecture series for Orthodontic/Pediatric dentistry resident, University of Kentuchy 2024)
  • Compromised epithelial actin dynamics underlie the etiology of an orofacial cleft in Baraitser Winter Syndrome with a missense mutation in ACTB
    (Edward H Angle Society of Orthodontics. Midwest Component. 94th Annual Meeting 2024)
  • 日常臨床に役立つ小児歯列咬合管理のツボ
    (第42回 日本小児歯科学会近畿地方大会 教育講演 2023)
  • Comprehensive orthodontic approach in syndromic rare diseases and craniofacial anomalies
    (The 9th World Prestigious Scholar Lecture Series / WPSLS , Seoul National University School of Dentistry 2023)
  • 希少遺伝性疾患を伴う顎変形症治療のチームアプローチ
    (広島大学歯学部口腔外科セミナー 2022)
more...
Education (4):
  • 2005 - 2007 Kyoto University Department of Biophysics, Graduate School of Science
  • 2003 - 2007 GRADUATE SCHOOL OF MEDICINE DENTISTRY AND PHARMACEUTICAL SCIENCES Department of Orthodontics
  • 2004 - 2005 RIKEN CDB Evolutionary Regeneration Biology Group
  • 1997 - 2003 Okayama University Department of Dentistry
Professional career (1):
  • PhD (Okayama University)
Work history (7):
  • 2022/04 - 現在 Graduate School of Dentistry, Osaka University Department of Orthodontics and Dentofacial Orthopedics Associate Professor
  • 2017/09 - 2022/03 Osaka University Dental Hospital Department of Orthodontics Lecturer
  • 2014/08 - 2017/08 Graduate School of Dentistry, Osaka University Department of Orthodontics and Dentofacial Orthopedics Assistant Professor
  • 2013/07 - 2014/07 University of Missouri-Kansas City Department of Orthodontics and Dentofacial Orthopedics Adjunct Assistant Professor
  • 2011/02 - 2014/07 Stowers Institute for Medical Research Craniofacial Development Lab (Trainor lab) Postdoctoral Research Associate
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Committee career (9):
  • 2023/10 - 現在 日本先天異常学会 Congenital Anomalies, Associate Editor
  • 2023/04 - 現在 日本先天異常学会 幹事
  • 2020/01 - 現在 日本先天異常学会 将来計画検討委員会
  • 2020/01 - 現在 日本先天異常学会 評議員
  • 2018/07 - 現在 未診断疾患イニシアチブ(IRUD) 臨床専門分科会メンバー(歯科)
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Awards (20):
  • 2023/05 - Poster award The function of retinoid signaling in establishing anteroposterior patterning in embryonic maxilla
  • 2022/07 - 大阪大学大学院歯学研究科 研究科長賞
  • 2021/11 - 第80回日本矯正歯科学会学術大会&第5回国際会議 優秀演題賞 Baraitser-Winter syndrome を引き起こすACTBの新規変異同定と機能解析
  • 2021/08 - The61st The Japanese Teratology Society Annual Meeting Excellent presentation award
  • 2020/10 - 大阪大学大学院歯学研究科 研究科長賞
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Association Membership(s) (9):
日本先天異常学会 ,  JAPANESE STOMATOLOGICAL SOCIETY ,  THE JAPAN SOCIETY OF HUMAN GENETICS ,  The Japanese Society for Jaw Deformities ,  JAPANESE CLEFT PALATE ASSOCIATION ,  International Association of Dental Research ,  JAPANESE ASSOCIATION FOR ORAL BIOLOGY ,  JAPANESE ORTHODONTIC SOCIETY ,  Angle Midwest E.H. Angle Society
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