Nagatake Takahiro

ナガタケタカヒロ | Nagatake Takahiro

Affiliation and department：
Other affiliations (2)：

Hiroshima University
National Institutes of Biomedical Innovation, Health and Nutrition

Research keywords (6)：炎症 , Mucosal immunity , Food immunology , Allergy , Vaccine , Lymphoid tissue organogenesis

Research theme for competitive and other funds (11)：

2023 - 2026 オメガ3脂肪酸摂取による免疫制御活性に腸内細菌は必要か?
2023 - 2024 ワクチン抗原特異的免疫応答における食事脂質の量と質の関与
2023 - 2024 腸管免疫を促進する母乳脂質の機能解析
2023 - 2024 オメガ3脂肪酸代謝物17,18-エポキシエイコサテトラエン酸による食物アレルギー抑制機構の解明
2020 - 2023 The effects of environmental chemicals on ocular immune systems

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Papers (51)：

Takahiro Moriyama, Makoto Yoritate, Naoki Kato, Azusa Saika, Wakana Kusuhara, Shunsuke Ono, Takahiro Nagatake, Hiroyuki Koshino, Noriaki Kiya, Natsuho Moritsuka, et al. Linkage-editing pseudo-glycans: A reductive α-fluorovinyl-C-glycosylation strategy to create glycan analogs with altered biological activities. Journal of the American Chemical Society. 2024
Xiao Sun, Koji Hosomi, Atsushi Shimoyama, Ken Yoshii, Azusa Saika, Haruki Yamaura, Takahiro Nagatake, Hiroshi Kiyono, Koichi Fukase, Jun Kunisawa. Alcaligenes lipid A functions as a superior mucosal adjuvant to monophosphoryl lipid A via the recruitment and activation of CD11b+ dendritic cells in nasal tissue. International Immunology. 2023
Shota Kajiyama, Takahiro Nagatake, Satoru Ishikawa, Koji Hosomi, Yuki Shimada, Yasunori Matsui, Jun Kunisawa. Lentinula Edodes Mycelia extract regulates the function of antigen-presenting cells to activate immune cells and prevent tumor-induced deterioration of immune function. BMC Complementary Medicine and Therapies. 2023. 23. 1. 281
Kei Ishida, Takahiro Nagatake, Azusa Saika, Soichiro Kawai, Eri Node, Koji Hosomi, Jun Kunisawa. Induction of unique macrophage subset by simultaneous stimulation with LPS and IL-4. Frontiers in Immunology. 2023. 14. 1111729
Yutaka Nakamura, Yozen Fuse, Seiga Komiyama, Takahiro Nagatake, Jun Kunisawa, Koji Hase. Dietary iodine attenuates allergic rhinitis by inducing ferroptosis in activated B cells. Scientific Reports. 2023. 13. 1

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Books (38)：

必須脂肪酸の代謝と免疫制御, 個人差
「実験医学増刊号: 健康社会を実現する精密栄養学」(羊土社) 2023
B細胞やT細胞の分化制御におけるビタミンB1の役割
「臨床免疫・アレルギー科」(科学評論社) 2023
免疫バランス制御におけるオメガ3脂肪酸代謝物の働きとメカニズム解明
「食品と開発」(インフォーママーケッツジャパン) 2022
腸内環境を介した免疫制御とアレルギー・炎症との関わり
「リンパ学」(日本リンパ学会) 2021
Diet-mediated Immune Regulation in the Skin
2021

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Lectures and oral presentations (53)：

免疫を制御する必須脂肪酸代謝物の新機能
(第12回分子状水素医学生物学会大会 2023)
必須脂肪酸代謝物の新たな免疫制御機構と腸内細菌の関与
(日本薬学会第143年会 2023)
必須脂肪酸の代謝による免疫・アレルギー・炎症の制御
(第96回日本薬理学会 2022)
必須脂肪酸代謝物の多彩な免疫制御活性と腸内細菌の関与
(第18回霊長類医科学フォーラム 2022)
Intestinal microbe-dependent omega-3 lipid metabolite alpha-KetoA prevents inflammatory diseases
(2021)

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Education (4)：

2006 - 2010 The University of Tokyo Graduate School of Medicine Department of Pathology, Immunology and Microbiology
2004 - 2006 The University of Tokyo Graduate School of Medicine Department of Medical Science
2000 - 2004 Meiji University School of Agriculture Department of Life Science
1996 - 1999 Narita High School

Professional career (1)：

博士(医学) (東京大学大学院)

Work history (11)：

2022/04 - 現在明治大学農学部生命科学科生体機構学研究室専任准教授
2018/04 - 2022/03 National Institutes of Biomedical Innovation, Health and Nutrition Center for Vaccine and Adjuvant Research, Laboratory of Vaccine Materials/Laboratory of Gut Environmental System Senior Scientist
2015/04 - 2018/03 National Institutes of Biomedical Innovation, Health and Nutrition Laboratory of Vaccine Materials/Laboratory of Gut Environmental System Scientist
2013/01 - 2015/03 National Institute of Biomedical Innovation Laboratory of Vaccine Materials Scientist
2012/04 - 2012/12 JSPS Research Fellowship for Young Scientists (PD)

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Awards (7)：

2022/12 - International Immunology Outstanding Merit Award 「Selective expression of claudin-5 in thymic endothelial cells regulates the blood-thymus barrier and T-cell export」
2021/06 - Research Encouragement Award from The Intestinal Microbiology Society
2017/12 - Japanese Society for Immunology Best Presentation Award 17,18-EpETE, a metabolite of omega-3 essential fatty acids, inhibited neutrophil mobility and ameliorated skin inflammation in DNFB-induced contact hypersensitivity model
2007/05 - The Institute of Medical Science, The University of Tokyo Best Poster Award
2005/06 - Society for Mucosal Immunology Young Investigator Award Different Organogenesis Associated Gene Expression between NALT and Peyer’s Patch CD3-CD4+CD45+ Inducer Cells

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Association Membership(s) (6)：

腸内細菌学会 , THE JAPANESE SOCIETY FOR IMMUNOLOGY , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , JAPANESE ASSOCIATION FOR FOOD IMMUNOLOGY , JAPANESE SOCIETY OF ANTI-AGING MEDICINE , THE PHARMACEUTICAL SOCIETY OF JAPAN

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